{"id":9388,"date":"2017-06-01T00:00:00","date_gmt":"2018-12-03T17:10:35","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/synephrine-as-a-specific-marker-for-orange-consumption\/"},"modified":"2018-12-03T18:10:35","modified_gmt":"2018-12-03T17:10:35","slug":"synephrine-as-a-specific-marker-for-orange-consumption","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/synephrine-as-a-specific-marker-for-orange-consumption\/","title":{"rendered":"Synephrine as a Specific Marker for Orange Consumption."},"content":{"rendered":"<p style=\"text-align:justify\">To validate the suitability of synephrine, known to be a highly abundant alkaloid in oranges, as a dietary biomarker for orange consumption, a highly sensitive and robust stable isotope dilution analysis (SIDA) as well as an ECHO method, using the analyte itself as a pseudointernal standard injected into the analysis run to provide an &quot;echo peak&quot; of the analyte, was developed to quantitate synephrine by liquid chromatography-tandem mass spectrometry (LC-MS\/MS) in citrus juices and human urine before and after the ingestion of orange juice. A citrus juice screening revealed high synephrine concentrations of 150-420 nmol\/mL in orange (n = 11) and tangerine (n = 2) juices, whereas 20-100 times lower levels were found in juice from grapefruit (n = 14), lemon (n = 5), pomelo (n = 2), and lime (n = 4). Application of the SIDA to quantitate synephrine in sulfatase\/glucuronidase-treated urine samples (n = 10) after orange juice consumption showed an increase of synephrine from trace levels (0.1 &plusmn; 0.1 nmol\/mL) in the 2-day washout phase to a maximum concentration of 8.9 (&plusmn;5.5) nmol\/mL found 4 h after ingestion of orange juice. Whereas proline betaine was recently reported as a dietary biomarker indicating the ingestion of any citrus product and Chinese artichoke, synephrine can be used a reliable additional biomarker with high specificity for orange and tangerine.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-9388","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Chair for Food Chemistry and Molecular Sensory Science, Technische Universit\u00e4t M\u00fcnchen , Lise-Meitner-Stra\u00dfe 34, D-85354 Freising, Germany.","annee":"2017","mois":"6","numero":"65:23","page":"4853-4858","auteurs":[{"ID":9384,"post_author":"0","post_date":"2018-12-03 18:10:33","post_date_gmt":"2018-12-03 17:10:33","post_content":"","post_title":"Matthias Bader","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"matthias-bader","to_ping":"","pinged":"","post_modified":"2018-12-03 18:10:33","post_modified_gmt":"2018-12-03 17:10:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/matthias-bader\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9385,"post_author":"0","post_date":"2018-12-03 18:10:33","post_date_gmt":"2018-12-03 17:10:33","post_content":"","post_title":"Tatjana Lang","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"tatjana-lang","to_ping":"","pinged":"","post_modified":"2018-12-03 18:10:33","post_modified_gmt":"2018-12-03 17:10:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/tatjana-lang\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9386,"post_author":"0","post_date":"2018-12-03 18:10:34","post_date_gmt":"2018-12-03 17:10:34","post_content":"","post_title":"Roman Lang","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"roman-lang","to_ping":"","pinged":"","post_modified":"2018-12-03 18:10:34","post_modified_gmt":"2018-12-03 17:10:34","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/roman-lang\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9387,"post_author":"0","post_date":"2018-12-03 18:10:34","post_date_gmt":"2018-12-03 17:10:34","post_content":"","post_title":"Thomas Hofmann","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"thomas-hofmann","to_ping":"","pinged":"","post_modified":"2018-12-03 18:10:34","post_modified_gmt":"2018-12-03 17:10:34","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/thomas-hofmann\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1648,"post_author":"0","post_date":"2018-12-03 16:01:16","post_date_gmt":"2018-12-03 15:01:16","post_content":"","post_title":"Journal of agricultural and food chemistry","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"journal-of-agricultural-and-food-chemistry","to_ping":"","pinged":"","post_modified":"2018-12-03 16:01:16","post_modified_gmt":"2018-12-03 15:01:16","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/journal-of-agricultural-and-food-chemistry\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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