{"id":9024,"date":"2017-06-01T00:00:00","date_gmt":"2018-12-03T17:06:30","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-intake-and-the-risk-of-cardiovascular-disease\/"},"modified":"2018-12-03T18:06:30","modified_gmt":"2018-12-03T17:06:30","slug":"fruit-and-vegetable-intake-and-the-risk-of-cardiovascular-disease","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-intake-and-the-risk-of-cardiovascular-disease\/","title":{"rendered":"Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality-a systematic review and dose-response meta-analysis of prospective studies."},"content":{"rendered":"

Background<\/strong>
\nQuestions remain about the strength and shape of the dose-response relationship between fruit and vegetable intake and risk of cardiovascular disease, cancer and mortality, and the effects of specific types of fruit and vegetables. We conducted a systematic review and meta-analysis to clarify these associations.<\/p>\n

Methods<\/strong>
\nPubMed and Embase were searched up to 29 September 2016. Prospective studies of fruit and vegetable intake and cardiovascular disease, total cancer and all-cause mortality were included. Summary relative risks (RRs) were calculated using a random effects model, and the mortality burden globally was estimated; 95 studies (142 publications) were included.<\/p>\n

Results<\/strong>
\nFor fruits and vegetables combined, the summary RR per 200 g\/day was 0.92 [95% confidence interval (CI): 0.90-0.94, I 2  = 0%, n  = 15] for coronary heart disease, 0.84 (95% CI: 0.76-0.92, I 2  = 73%, n  = 10) for stroke, 0.92 (95% CI: 0.90-0.95, I 2  = 31%, n  = 13) for cardiovascular disease, 0.97 (95% CI: 0.95-0.99, I 2  = 49%, n  = 12) for total cancer and 0.90 (95% CI: 0.87-0.93, I 2  = 83%, n  = 15) for all-cause mortality. Similar associations were observed for fruits and vegetables separately. Reductions in risk were observed up to 800 g\/day for all outcomes except cancer (600 g\/day). Inverse associations were observed between the intake of apples and pears, citrus fruits, green leafy vegetables, cruciferous vegetables, and salads and cardiovascular disease and all-cause mortality, and between the intake of green-yellow vegetables and cruciferous vegetables and total cancer risk. An estimated 5.6 and 7.8 million premature deaths worldwide in 2013 may be attributable to a fruit and vegetable intake below 500 and 800 g\/day, respectively, if the observed associations are causal.<\/p>\n

Conclusions<\/strong>
\nFruit and vegetable intakes were associated with reduced risk of cardiovascular disease, cancer and all-cause mortality. These results support public health recommendations to increase fruit and vegetable intake for the prevention of cardiovascular disease, cancer, and premature mortality.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-9024","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway.","annee":"2017","mois":"6","numero":"46:3","page":"1029-1056","auteurs":[{"ID":1326,"post_author":"0","post_date":"2018-12-03 15:58:22","post_date_gmt":"2018-12-03 14:58:22","post_content":"","post_title":"Elio Riboli","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"elio-riboli","to_ping":"","pinged":"","post_modified":"2018-12-03 15:58:22","post_modified_gmt":"2018-12-03 14:58:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/elio-riboli\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9017,"post_author":"0","post_date":"2018-12-03 18:06:26","post_date_gmt":"2018-12-03 17:06:26","post_content":"","post_title":"Teresa Norat","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"teresa-norat","to_ping":"","pinged":"","post_modified":"2018-12-03 18:06:26","post_modified_gmt":"2018-12-03 17:06:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/teresa-norat\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9018,"post_author":"0","post_date":"2018-12-03 18:06:27","post_date_gmt":"2018-12-03 17:06:27","post_content":"","post_title":"Dagfinn Aune","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"dagfinn-aune","to_ping":"","pinged":"","post_modified":"2018-12-03 18:06:27","post_modified_gmt":"2018-12-03 17:06:27","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/dagfinn-aune\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":4189,"post_author":"0","post_date":"2018-12-03 17:13:16","post_date_gmt":"2018-12-03 16:13:16","post_content":"","post_title":"Darren C Greenwood","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"darren-c-greenwood","to_ping":"","pinged":"","post_modified":"2018-12-03 17:13:16","post_modified_gmt":"2018-12-03 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Boffetta","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"paolo-boffetta","to_ping":"","pinged":"","post_modified":"2018-12-03 17:12:19","post_modified_gmt":"2018-12-03 16:12:19","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/paolo-boffetta\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9020,"post_author":"0","post_date":"2018-12-03 18:06:28","post_date_gmt":"2018-12-03 17:06:28","post_content":"","post_title":"Lars T Fadnes","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lars-t-fadnes","to_ping":"","pinged":"","post_modified":"2018-12-03 18:06:28","post_modified_gmt":"2018-12-03 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Vatten","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lars-j-vatten","to_ping":"","pinged":"","post_modified":"2018-12-03 18:06:29","post_modified_gmt":"2018-12-03 17:06:29","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/lars-j-vatten\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9023,"post_author":"0","post_date":"2018-12-03 18:06:29","post_date_gmt":"2018-12-03 17:06:29","post_content":"","post_title":"Serena Tonstad","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"serena-tonstad","to_ping":"","pinged":"","post_modified":"2018-12-03 18:06:29","post_modified_gmt":"2018-12-03 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