{"id":7614,"date":"2018-02-01T00:00:00","date_gmt":"2018-12-03T16:51:04","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/feasibility-study-to-assess-the-impact-of-a-lifestyle-intervention\/"},"modified":"2018-12-03T17:51:04","modified_gmt":"2018-12-03T16:51:04","slug":"feasibility-study-to-assess-the-impact-of-a-lifestyle-intervention","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/feasibility-study-to-assess-the-impact-of-a-lifestyle-intervention\/","title":{"rendered":"Feasibility study to assess the impact of a lifestyle intervention (&lsquo;LivingWELL&rsquo;) in people having an assessment of their family history of colorectal or breast cancer."},"content":{"rendered":"<p style=\"text-align:justify\"><strong>OBJECTIVES<\/strong><br \/>\nTo assess the feasibility of delivering and evaluating a weight management (WM) programme for overweight patients with a family history (FH) of breast cancer (BC) or colorectal cancer (CRC).<\/p>\n<p style=\"text-align:justify\"><strong>STUDY DESIGN<\/strong><br \/>\nA two-arm (intervention vs usual care) randomised controlled trial.<\/p>\n<p style=\"text-align:justify\"><strong>SETTING<\/strong><br \/>\nNational Health Service (NHS) Tayside and NHS Grampian.<\/p>\n<p style=\"text-align:justify\"><strong>PARTICIPANTS<\/strong><br \/>\nPeople with a FH of BC or CRC aged&ge;18 years and body mass index of &ge;25&thinsp;kg\/m<\/p>\n<p style=\"text-align:justify\"><strong>INTERVENTION<\/strong><br \/>\nParticipants were randomised to a control (lifestyle booklet) or 12-week intervention arm where they were given one face-to-face counselling session, four telephone consultations and web-based support. A goal of 5% reduction in body weight was set, and a personalised diet and physical activity (PA) programme was provided. Behavioural change techniques (motivational interviewing, action and coping plans and implementation intentions) were used.<\/p>\n<p style=\"text-align:justify\"><strong>PRIMARY OUTCOME<\/strong><br \/>\nFeasibility measures: recruitment, programme implementation, fidelity measures, achieved measurements and retention, participant satisfaction assessed by questionnaire and qualitative interviews.<\/p>\n<p style=\"text-align:justify\"><strong>SECONDARY OUTCOMES<\/strong><br \/>\nMeasured changes in weight and PA and reported diet and psychosocial measures between baseline and 12-week follow-up.<\/p>\n<p style=\"text-align:justify\"><strong>RESULTS<\/strong><br \/>\nOf 480 patients approached, 196 (41%) expressed interest in the study, and of those, 78 (40%) patients were randomised. Implementation of the programme was challenging within the time allotted and fidelity to the intervention modest (62%). Qualitative findings indicated the programme was well received. Questionnaires and anthropometric data were completed by &gt;98%. Accelerometer data were attained by 84% and 54% at baseline and follow-up, respectively. Retention at 12 weeks was 76%. Overall, 36% of the intervention group (vs 0% in control) achieved 5%&thinsp;weight loss. Favourable increases in PA and reduction in dietary fat were also reported.<\/p>\n<p style=\"text-align:justify\"><strong>CONCLUSIONS<\/strong><br \/>\nA lifestyle programme for people with a family history of cancer is feasible to conduct and acceptable to participants, and indicative results suggest favourable outcomes.<\/p>\n<p style=\"text-align:justify\"><strong>TRIAL REGISTRATION NUMBER<\/strong><br \/>\nISRCTN13123470; Pre-results.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-7614","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Centre for Research into Cancer Prevention and Screening \/ Tayside Cancer Centre, Division of Cancer Research, University of Dundee, Ninewells Hospital & Medical School, Dundee, UK.","annee":"2018","mois":"2","numero":"8:2","page":"","auteurs":[{"ID":3523,"post_author":"0","post_date":"2018-12-03 17:06:29","post_date_gmt":"2018-12-03 16:06:29","post_content":"","post_title":"Annie S 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Gallant","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"stephanie-gallant","to_ping":"","pinged":"","post_modified":"2018-12-03 17:51:02","post_modified_gmt":"2018-12-03 16:51:02","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/stephanie-gallant\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":7610,"post_author":"0","post_date":"2018-12-03 17:51:02","post_date_gmt":"2018-12-03 16:51:02","post_content":"","post_title":"Zosia Miedzybrodzka","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"zosia-miedzybrodzka","to_ping":"","pinged":"","post_modified":"2018-12-03 17:51:02","post_modified_gmt":"2018-12-03 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O'Carroll","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ronan-e-ocarroll","to_ping":"","pinged":"","post_modified":"2018-12-03 17:51:03","post_modified_gmt":"2018-12-03 16:51:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ronan-e-ocarroll\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":7612,"post_author":"0","post_date":"2018-12-03 17:51:03","post_date_gmt":"2018-12-03 16:51:03","post_content":"","post_title":"Sarah Vinnicombe","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sarah-vinnicombe","to_ping":"","pinged":"","post_modified":"2018-12-03 17:51:03","post_modified_gmt":"2018-12-03 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