{"id":7338,"date":"2018-01-01T00:00:00","date_gmt":"2018-12-03T16:48:02","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/mediating-effects-of-metabolic-factors-on-the-association\/"},"modified":"2018-12-03T17:48:02","modified_gmt":"2018-12-03T16:48:02","slug":"mediating-effects-of-metabolic-factors-on-the-association","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/mediating-effects-of-metabolic-factors-on-the-association\/","title":{"rendered":"Mediating effects of metabolic factors on the association between fruit or vegetable intake and cardiovascular disease: the Korean National Health and Nutrition Examination Survey."},"content":{"rendered":"<p style=\"text-align:justify\"><strong>OBJECTIVE<\/strong><br \/>\nWe assessed the mediating effects of metabolic components on the relationship between fruit or vegetable intake and cardiovascular disease (CVD).<\/p>\n<p style=\"text-align:justify\"><strong>DESIGN<\/strong><br \/>\nCross-sectional study.<\/p>\n<p style=\"text-align:justify\"><strong>SETTING<\/strong><br \/>\nThis study was conducted using data from the 2013-2015 Korean National Health and Nutrition Examination Survey, which is a national representative cross-sectional survey to assess health and nutritional status in the Korean population.<\/p>\n<p style=\"text-align:justify\"><strong>METHOD AND ANALYSIS<\/strong><br \/>\nA total of 9040 subjects (3555 males and 5485 females) aged &ge;25 years were included in the study. Physician-diagnosed CVD via self-report was used as the outcome. Fruit or vegetable intake was measured via a dish-based semiquantitative food frequency questionnaire and grouped into categories (&lt;1&thinsp;time\/day, 1 time\/day, 2 times\/day and &ge;3&thinsp;times\/day). Systolic blood pressure (SBP), cholesterol and fasting glucose were considered metabolic mediators, and the bootstrap method was used to assess mediating effect.<\/p>\n<p style=\"text-align:justify\"><strong>RESULTS<\/strong><br \/>\nAbout 1.8% of adults aged 25-64&thinsp;years had CVD. According to the result of &#039;process&#039; macro, the confounder-adjusted risk for CVD decreased by 14% (OR=0.86, 95% CI 0.74 to 0.98) as fruit, but not vegetable, intake was increased by one unit per day. After additional adjustment for three metabolic factors simultaneously, the OR was attenuated to 0.89 (95% CI 0.77 to 1.03). This result indicates that the indirect effect of three metabolic factors accounted for 21.4% of the relationship between fruit intake and CVD. SBP was a more important metabolic mediator than the other factors. The indirect effect by metabolic factors accounted for 30.0% when body mass index was additionally controlled as a mediator, and SBP still had an independent effect compared with the other mediators.<\/p>\n<p style=\"text-align:justify\"><strong>CONCLUSIONS<\/strong><br \/>\nOur results indicate that controlling SBP may lessen the CVD risk, and a diet rich in fruits can regulate SBP which, in turn, reduces CVD risk.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-7338","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Clinical Trial Center, Mokdong Hospital, Ewha Womans University, Seoul, South Korea.","annee":"2018","mois":"0","numero":"8:2","page":"","auteurs":[{"ID":7335,"post_author":"0","post_date":"2018-12-03 17:48:00","post_date_gmt":"2018-12-03 16:48:00","post_content":"","post_title":"Kyungwon Oh","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"kyungwon-oh","to_ping":"","pinged":"","post_modified":"2018-12-03 17:48:00","post_modified_gmt":"2018-12-03 16:48:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/kyungwon-oh\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":2749,"post_author":"0","post_date":"2018-12-03 16:58:48","post_date_gmt":"2018-12-03 15:58:48","post_content":"","post_title":"Hyesook Park","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hyesook-park","to_ping":"","pinged":"","post_modified":"2018-12-03 16:58:48","post_modified_gmt":"2018-12-03 15:58:48","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hyesook-park\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":2750,"post_author":"0","post_date":"2018-12-03 16:58:49","post_date_gmt":"2018-12-03 15:58:49","post_content":"","post_title":"Hye Ah Lee","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hye-ah-lee","to_ping":"","pinged":"","post_modified":"2018-12-03 16:58:49","post_modified_gmt":"2018-12-03 15:58:49","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hye-ah-lee\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":7336,"post_author":"0","post_date":"2018-12-03 17:48:01","post_date_gmt":"2018-12-03 16:48:01","post_content":"","post_title":"Dohee Lim","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"dohee-lim","to_ping":"","pinged":"","post_modified":"2018-12-03 17:48:01","post_modified_gmt":"2018-12-03 16:48:01","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/dohee-lim\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":7337,"post_author":"0","post_date":"2018-12-03 17:48:01","post_date_gmt":"2018-12-03 16:48:01","post_content":"","post_title":"Eun Jung Kim","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"eun-jung-kim","to_ping":"","pinged":"","post_modified":"2018-12-03 17:48:01","post_modified_gmt":"2018-12-03 16:48:01","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/eun-jung-kim\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":2635,"post_author":"0","post_date":"2018-12-03 16:57:37","post_date_gmt":"2018-12-03 15:57:37","post_content":"","post_title":"BMJ open","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"bmj-open","to_ping":"","pinged":"","post_modified":"2018-12-03 16:57:37","post_modified_gmt":"2018-12-03 15:57:37","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/bmj-open\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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