{"id":61654,"date":"2013-12-01T00:00:00","date_gmt":"2018-12-04T08:00:37","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/healthy-lifestyles-reduce-the-incidence-of-chronic-diseases\/"},"modified":"2018-12-04T09:00:37","modified_gmt":"2018-12-04T08:00:37","slug":"healthy-lifestyles-reduce-the-incidence-of-chronic-diseases","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/healthy-lifestyles-reduce-the-incidence-of-chronic-diseases\/","title":{"rendered":"Healthy lifestyles reduce the incidence of chronic diseases and dementia: evidence from the caerphilly cohort study."},"content":{"rendered":"<p><strong>BACKGROUND<\/strong><br \/>\nHealthy lifestyles based on non-smoking, an acceptable BMI, a high fruit and vegetable intake, regular physical activity, and low\/moderate alcohol intake, are associated with reductions in the incidence of certain chronic diseases, but to date there is limited evidence on cognitive function and dementia.<\/p>\n<p><strong>METHODS<\/strong><br \/>\nIn 1979 healthy behaviours were recorded on 2,235 men aged 45-59 years in Caerphilly, UK. During the following 30 years incident diabetes, vascular disease, cancer and death were recorded, and in 2004 cognitive state was determined.<\/p>\n<p><strong>RESULTS<\/strong><br \/>\nMen who followed four or five of the behaviours had an odds ratio (OR) and confidence intervals (CI) for diabetes, corrected for age and social class, of 0.50 (95% CI: 0.19, 1.31; P for trend with increasing numbers of healthy behaviours &lt;0.0005). For vascular disease the OR was 0.50 (95% CI: 0.30, 0.84; P for trend &lt;0.0005), and there was a delay in vascular disease events of up to 12 years. Cancer incidence was not significantly related to lifestyle although there was a reduction associated with non-smoking (OR: 0.65; 95% CI: 0.54, 0.79). All-cause mortality was reduced in men following four or five behaviours (OR 0.40; 95% CI: 0.24, 0.67; P for trend &lt;0.005). After further adjustment for NART, the OR for men following four or five healthy behaviours was 0.36 (95% CI: 0.12, 1.09; P for trend &lt;0.001) for cognitive impairment, and 0.36 (95% CI: 0.07, 1.99; P for trend &lt;0.02) for dementia. The adoption of a healthy lifestyle by men was low and appears not to have changed during the subsequent 30 years, with under 1% of men following all five of the behaviours and 5% reporting four or more in 1979 and in 2009.<\/p>\n<p><strong>CONCLUSIONS<\/strong><br \/>\nA healthy lifestyle is associated with increased disease-free survival and reduced cognitive impairment but the uptake remains low.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-61654","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Cochrane Institute of Primary Care and Public Health, Cardiff University, Cardiff, United Kingdom.","annee":"2013","mois":"12","numero":"8:12","page":"e81877","auteurs":[{"ID":61648,"post_author":"0","post_date":"2018-12-04 09:00:33","post_date_gmt":"2018-12-04 08:00:33","post_content":"","post_title":"Peter 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