{"id":61630,"date":"2014-04-01T00:00:00","date_gmt":"2018-12-04T08:00:15","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/oral-and-systemic-photoprotection\/"},"modified":"2018-12-04T09:00:15","modified_gmt":"2018-12-04T08:00:15","slug":"oral-and-systemic-photoprotection","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/oral-and-systemic-photoprotection\/","title":{"rendered":"Oral and systemic photoprotection."},"content":{"rendered":"<p>Photoprotection can be provided not only by UV blockers, but also by oral substances. Epidemiologically identified associations between foods and skin cancer and experimental intervention experiments have discovered mechanisms of UV skin damage. These approaches have identified oral substances that are photoprotective in humans. UV inhibits ATP production causing an energy crisis, which prevents optimal skin immunity and DNA repair. Enhancing ATP production with oral nicotinamide protects from UV immunosuppression, enhances DNA repair, and reduces skin cancer in humans. Reactive oxygen species also contribute to photodamage. Nontoxic substances consumed in the diet, or available as oral supplements, can protect the skin by multiple potential mechanisms. These substances include polyphenols in fruit, vegetables, wine, tea and caffeine containing foods. UV-induced prostaglandin E2 (PGE2 ) contributes to photodamage.<\/p>\n<p>Non-steroidal anti-inflammatory drugs and food substances reduce production of this lipid mediator. Fish oils are photoprotective, at least partially by reducing PGE2 . Orally consumed substances, either in the diet, or as supplements, can influence cutaneous responses to UV. A current research goal is to develop an oral supplement that could be used in conjunction with other sun protective strategies in order to provide improved protection from sunlight.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-61630","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Discipline of Dermatology, Bosch Institute, Central Clinical School, University of Sydney, and Dermatology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, Australia.","annee":"2014","mois":"4","numero":"30:2-3","page":"102-111","auteurs":[{"ID":61626,"post_author":"0","post_date":"2018-12-04 09:00:12","post_date_gmt":"2018-12-04 08:00:12","post_content":"","post_title":"Andrew C Chen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"andrew-c-chen","to_ping":"","pinged":"","post_modified":"2018-12-04 09:00:12","post_modified_gmt":"2018-12-04 08:00:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/andrew-c-chen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":61627,"post_author":"0","post_date":"2018-12-04 09:00:13","post_date_gmt":"2018-12-04 08:00:13","post_content":"","post_title":"Diona L Damian","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"diona-l-damian","to_ping":"","pinged":"","post_modified":"2018-12-04 09:00:13","post_modified_gmt":"2018-12-04 08:00:13","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/diona-l-damian\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":61628,"post_author":"0","post_date":"2018-12-04 09:00:14","post_date_gmt":"2018-12-04 08:00:14","post_content":"","post_title":"Gary M Halliday","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"gary-m-halliday","to_ping":"","pinged":"","post_modified":"2018-12-04 09:00:14","post_modified_gmt":"2018-12-04 08:00:14","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/gary-m-halliday\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":61629,"post_author":"0","post_date":"2018-12-04 09:00:14","post_date_gmt":"2018-12-04 08:00:14","post_content":"","post_title":"Photodermatology, photoimmunology &amp; photomedicine","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"photodermatology-photoimmunology-photomedicine","to_ping":"","pinged":"","post_modified":"2018-12-04 09:00:14","post_modified_gmt":"2018-12-04 08:00:14","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/photodermatology-photoimmunology-photomedicine\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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