{"id":61625,"date":"2014-01-01T00:00:00","date_gmt":"2018-12-04T08:00:11","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/influence-of-conventional-cardiovascular-risk-factors-and\/"},"modified":"2018-12-04T09:00:11","modified_gmt":"2018-12-04T08:00:11","slug":"influence-of-conventional-cardiovascular-risk-factors-and","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/influence-of-conventional-cardiovascular-risk-factors-and\/","title":{"rendered":"Influence of Conventional Cardiovascular Risk Factors and Lifestyle Characteristics on Cardiovascular Disease After Hematopoietic Cell Transplantation."},"content":{"rendered":"

OBJECTIVE<\/strong>
\nTo determine the influence of modifiable lifestyle factors on the risk of cardiovascular disease after hematopoietic cell transplantation (HCT).<\/p>\n

PATIENTS AND METHODS<\/strong>
\nHCT survivors of ≥ 1 year treated from 1970 to 2010 (n = 3,833) were surveyed from 2010 to 2011 on current cardiovascular health and related lifestyle factors (smoking, diet, recreational physical activity).<\/p>\n

Responses (n = 2,362) were compared with those from a matched general population sample (National Health and Nutrition Examination Survey [NHANES]; n = 1,192).<\/p>\n

RESULTS<\/strong>
\nCompared with NHANES participants, HCT survivors (median age, 55.9 years; median 10.8 years since HCT; 71.3% allogeneic) had higher rates of cardiomyopathy (4.0% v 2.6%), stroke (4.8% v 3.3%), dyslipidemia (33.9% v 22.3%), and diabetes (14.3% v 11.7%; P < .05 for all comparisons). Prevalence of hypertension was similar (27.9% v 30.0%), and survivors were less likely to have ischemic heart disease (6.1% v 8.9%; P < .01). Among HCT survivors, hypertension, dyslipidemia, and diabetes were independent risk factors for ischemic heart disease and cardiomyopathy, and smoking was associated with ischemic heart disease and diabetes (odds ratios [ORs], 1.8 to 2.1; P = .02). Obesity was a risk factor for post-transplantation hypertension, dyslipidemia, and diabetes (ORs ≥ 2.0; P < .001). In contrast, lower fruit\/vegetable intake was associated with greater risk of dyslipidemia and diabetes (ORs, 1.4 to 1.8; P ≤ .01), and lower physical activity level was associated with greater risk of hypertension and diabetes (ORs, 1.4 to 1.5; P < .05). Healthier lifestyle characteristics among HCT survivors attenuated risk of all cardiovascular conditions assessed.<\/p>\n

CONCLUSIONS<\/strong>
\nAttention of clinicians to conventional cardiovascular risk factors and modifiable lifestyle characteristics offers hope of reducing serious cardiovascular morbidity after HCT.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-61625","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Eric J. Chow, K. Scott Baker, Stephanie J. Lee, Mary E.D. Flowers, Kara L. Cushing-Haugen, Yoshihiro Inamoto, Wendy M. Leisenring, Karen L. Syrjala, and Paul J. Martin, Fred Hutchinson Cancer Research Center; Eric J. Chow, K. Scott Baker, Seattle Children's Hospital; Eric J. Chow, K. Scott Baker, Stephanie J. Lee, Mary E.D. Flowers, and Paul J. Martin, University of Washington, Seattle, WA; and Nandita Khera, Mayo Clinic, Phoenix, AZ.","annee":"2014","mois":"1","numero":"32:3","page":"191-198","auteurs":[{"ID":61616,"post_author":"0","post_date":"2018-12-04 09:00:05","post_date_gmt":"2018-12-04 08:00:05","post_content":"","post_title":"Eric J Chow","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"eric-j-chow","to_ping":"","pinged":"","post_modified":"2018-12-04 09:00:05","post_modified_gmt":"2018-12-04 08:00:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/eric-j-chow\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":61617,"post_author":"0","post_date":"2018-12-04 09:00:06","post_date_gmt":"2018-12-04 08:00:06","post_content":"","post_title":"K Scott Baker","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"k-scott-baker","to_ping":"","pinged":"","post_modified":"2018-12-04 09:00:06","post_modified_gmt":"2018-12-04 08:00:06","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/k-scott-baker\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":58116,"post_author":"0","post_date":"2018-12-04 07:50:00","post_date_gmt":"2018-12-04 06:50:00","post_content":"","post_title":"Stephanie J Lee","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"stephanie-j-lee","to_ping":"","pinged":"","post_modified":"2018-12-04 07:50:00","post_modified_gmt":"2018-12-04 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Cushing-haugen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"kara-l-cushing-haugen","to_ping":"","pinged":"","post_modified":"2018-12-04 09:00:07","post_modified_gmt":"2018-12-04 08:00:07","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/kara-l-cushing-haugen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":61620,"post_author":"0","post_date":"2018-12-04 09:00:08","post_date_gmt":"2018-12-04 08:00:08","post_content":"","post_title":"Yoshihiro Inamoto","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"yoshihiro-inamoto","to_ping":"","pinged":"","post_modified":"2018-12-04 09:00:08","post_modified_gmt":"2018-12-04 08:00:08","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/yoshihiro-inamoto\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":61621,"post_author":"0","post_date":"2018-12-04 09:00:09","post_date_gmt":"2018-12-04 08:00:09","post_content":"","post_title":"Nandita Khera","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"nandita-khera","to_ping":"","pinged":"","post_modified":"2018-12-04 09:00:09","post_modified_gmt":"2018-12-04 08:00:09","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/nandita-khera\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":61622,"post_author":"0","post_date":"2018-12-04 09:00:09","post_date_gmt":"2018-12-04 08:00:09","post_content":"","post_title":"Wendy M 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