{"id":60701,"date":"2013-12-01T00:00:00","date_gmt":"2018-12-04T07:44:44","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/mediterranean-diet-and-cardiovascular-disease-historical\/"},"modified":"2018-12-04T08:44:44","modified_gmt":"2018-12-04T07:44:44","slug":"mediterranean-diet-and-cardiovascular-disease-historical","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/mediterranean-diet-and-cardiovascular-disease-historical\/","title":{"rendered":"Mediterranean diet and cardiovascular disease: historical perspective and latest evidence."},"content":{"rendered":"

The concept that the Mediterranean diet was associated with a lower incidence of cardiovascular disease (CVD) was first proposed in the 1950s. Since then, there have been randomized controlled trials and large epidemiological studies that reported associations with lower CVD: in 1994 and 1999, the reports of the intermediate and final analyses of the trial Lyon Diet Heart Study; in 2003, a major epidemiological study in Greece showing a strong inverse association between a Mediterranean score and the risk of cardiovascular complications; in 2011-2012, several reports showing that even non-Mediterranean populations can gain benefits from long-term adhesion to the Mediterranean diet; and in 2013, the PREDIMED trial showing a significant risk reduction in a low-risk population. Contrary to the pharmacological approach of cardiovascular prevention, the adoption of the Mediterranean diet has been associated with a significant reduction in new cancers and overall mortality. Thus, in terms of evidence-based medicine, the full adoption of a modern version of the Mediterranean diet pattern can be considered one of the most effective approaches for the prevention of fatal and nonfatal CVD complications.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-60701","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Laboratoire C?ur et Nutrition, TIMC-IMAG CNRS 5525, Facult\u00e9 de M\u00e9decine de Grenoble, Universit\u00e9 Joseph Fourier, 38054, La Tronche, France, michel.delorgeril@ujf-grenoble.fr.","annee":"2013","mois":"12","numero":"15:12","page":"370","auteurs":[{"ID":32211,"post_author":"0","post_date":"2018-12-03 23:56:04","post_date_gmt":"2018-12-03 22:56:04","post_content":"","post_title":"Michel De Lorgeril","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"michel-de-lorgeril","to_ping":"","pinged":"","post_modified":"2018-12-03 23:56:04","post_modified_gmt":"2018-12-03 22:56:04","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/michel-de-lorgeril\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":4111,"post_author":"0","post_date":"2018-12-03 17:12:29","post_date_gmt":"2018-12-03 16:12:29","post_content":"","post_title":"Current atherosclerosis reports","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"current-atherosclerosis-reports","to_ping":"","pinged":"","post_modified":"2018-12-03 17:12:29","post_modified_gmt":"2018-12-03 16:12:29","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/current-atherosclerosis-reports\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nMediterranean diet and cardiovascular disease: historical perspective and latest evidence. - 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