{"id":60382,"date":"2013-08-01T00:00:00","date_gmt":"2018-12-04T07:38:54","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/unhealthy-dietary-patterns-associated-with-inflammation\/"},"modified":"2018-12-04T08:38:54","modified_gmt":"2018-12-04T07:38:54","slug":"unhealthy-dietary-patterns-associated-with-inflammation","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/unhealthy-dietary-patterns-associated-with-inflammation\/","title":{"rendered":"Unhealthy dietary patterns associated with inflammation and endothelial dysfunction in type 1 diabetes: the EURODIAB study."},"content":{"rendered":"<p><strong>BACKGROUND AND AIMS<\/strong><br \/>\nA healthy diet has been inversely associated with endothelial dysfunction (ED) and low-grade inflammation (LGI). We investigated the association between nutrient consumption and biomarkers of ED and LGI in type 1 diabetes.<\/p>\n<p><strong>METHODS AND RESULTS<\/strong><br \/>\nWe investigated 491 individuals. Nutrient consumption and lifestyle risk factors were measured in 1989 and 1997. Biomarkers of ED (von Willebrand factor, soluble vascular cell adhesion molecule-1 and soluble endothelial selectin) and LGI (C-reactive protein, interleukin 6 and tumour necrosis factor &alpha;) were measured in 1997 and averaged into Z-scores. The nutrient residual method was used to adjust individual nutrient intake for energy intake. Data were analysed with generalised estimation equations. We report increments\/decrements in nutrient consumption, averaged over time, per +1 standard deviation (SD) of 1997 ED or LGI Z-scores, after adjustment for sex, age, duration of diabetes, investigation centre, body mass index, energy intake, smoking behaviour, alcohol consumption, and each of the other nutrients. One SD elevation in ED Z-score was associated with a diet lower in fibre [&beta;(95%CI);-0.09(-0.18;-0.004)], polyunsaturated fat [-0.18(-0.31;-0.05)] and vegetable protein [-0.10(-0.20;-0.001)]. For the LGI Z-score results showed associations with fibre [-0.09(-0.17;-0.01)], polyunsaturated fat [-0.14(-0.24;-0.03)] and cholesterol [0.10(0.01; 0.18)].<\/p>\n<p><strong>CONCLUSIONS<\/strong><br \/>\nIn type 1 diabetes, consumption of less fibre, polyunsaturated fat and vegetable protein, and more cholesterol over the study period was associated with more ED and LGI. Following dietary guidelines in type 1 diabetes may reduce cardiovascular disease risk by favourably affecting ED and LGI.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-60382","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Medicine, Maastricht University Medical Centre+, Maastricht, The Netherlands. b.vanbussel@maastrichtuniversity.nl","annee":"2013","mois":"8","numero":"23:8","page":"758-764","auteurs":[{"ID":5039,"post_author":"0","post_date":"2018-12-03 17:23:37","post_date_gmt":"2018-12-03 16:23:37","post_content":"","post_title":"B C T Van Bussel","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"b-c-t-van-bussel","to_ping":"","pinged":"","post_modified":"2018-12-03 17:23:37","post_modified_gmt":"2018-12-03 16:23:37","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/b-c-t-van-bussel\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":5040,"post_author":"0","post_date":"2018-12-03 17:23:37","post_date_gmt":"2018-12-03 16:23:37","post_content":"","post_title":"R M A Henry","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"r-m-a-henry","to_ping":"","pinged":"","post_modified":"2018-12-03 17:23:37","post_modified_gmt":"2018-12-03 16:23:37","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/r-m-a-henry\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":5041,"post_author":"0","post_date":"2018-12-03 17:23:38","post_date_gmt":"2018-12-03 16:23:38","post_content":"","post_title":"C G Schalkwijk","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"c-g-schalkwijk","to_ping":"","pinged":"","post_modified":"2018-12-03 17:23:38","post_modified_gmt":"2018-12-03 16:23:38","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/c-g-schalkwijk\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":14563,"post_author":"0","post_date":"2018-12-03 19:11:14","post_date_gmt":"2018-12-03 18:11:14","post_content":"","post_title":"Isabel M P L V O Ferreira","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"isabel-m-p-l-v-o-ferreira","to_ping":"","pinged":"","post_modified":"2018-12-03 19:11:14","post_modified_gmt":"2018-12-03 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Toeller","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"m-toeller","to_ping":"","pinged":"","post_modified":"2018-12-04 07:20:02","post_modified_gmt":"2018-12-04 06:20:02","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/m-toeller\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":47718,"post_author":"0","post_date":"2018-12-04 04:21:12","post_date_gmt":"2018-12-04 03:21:12","post_content":"","post_title":"J H Fuller","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-h-fuller","to_ping":"","pinged":"","post_modified":"2018-12-04 04:21:12","post_modified_gmt":"2018-12-04 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Soedamah-Muthu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sabita-s-soedamah-muthu","to_ping":"","pinged":"","post_modified":"2018-12-03 17:47:55","post_modified_gmt":"2018-12-03 16:47:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sabita-s-soedamah-muthu\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":6426,"post_author":"0","post_date":"2018-12-03 17:38:11","post_date_gmt":"2018-12-03 16:38:11","post_content":"","post_title":"Nutrition, metabolism, and cardiovascular diseases : NMCD","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"nutrition-metabolism-and-cardiovascular-diseases-nmcd","to_ping":"","pinged":"","post_modified":"2018-12-03 17:38:11","post_modified_gmt":"2018-12-03 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