{"id":59320,"date":"2014-03-01T00:00:00","date_gmt":"2018-12-04T07:20:52","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/allium-vegetables-and-garlic-supplements-do-not-reduce-risk\/"},"modified":"2018-12-04T08:20:52","modified_gmt":"2018-12-04T07:20:52","slug":"allium-vegetables-and-garlic-supplements-do-not-reduce-risk","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/allium-vegetables-and-garlic-supplements-do-not-reduce-risk\/","title":{"rendered":"Allium Vegetables and Garlic Supplements do Not Reduce Risk of Colorectal Cancer, Based on Meta-analysis of Prospective Studies."},"content":{"rendered":"<p style=\"text-align:justify\"><strong>BACKGROUND<\/strong> <strong>&amp; AIMS<\/strong><br \/>\nLaboratory studies have provided evidence that allium vegetables and garlic supplements might protect against colorectal cancer (CRC), but epidemiologic studies have produced inconsistent findings.<\/p>\n<p style=\"text-align:justify\"><strong>METHODS<\/strong><br \/>\nWe conducted a meta-analysis of prospective studies evaluating the associations between allium vegetables, garlic supplements, and CRC risk. We pooled effect measures using fixed or random-effect models, assessing the highest vs the lowest intakes. We used a dose-response regression model to evaluate the relationship between allium vegetable intake and CRC risk.<\/p>\n<p style=\"text-align:justify\"><strong>RESULTS<\/strong><br \/>\nOur analysis included 8 studies with 20 reports of the effects of allium vegetables (5458 patients with CRC and 7125067 person-years) and 5 studies with 11 reports of the effects of garlic supplements (2685 patients with CRC and 2304439 person-years). We found no association between higher intake of allium vegetables and CRC risk (relative risk [RR]=1.06; 95% confidence interval [CI], 0.96-1.17; P=.26). Intake of allium vegetables did not correspond to CRC risk (P for nonlinear=.24, P for linear=.20). In subgroup analysis, higher consumption of allium vegetables was marginally associated with increased risk of colon cancer among women (RR=1.23; 95% CI, 1.01-1.50; P=.05). Use of garlic supplements was significantly associated with an increased risk of CRC (RR=1.18; 95% CI, 1.02-1.36; P=.03).<\/p>\n<p style=\"text-align:justify\"><strong>CONCLUSION<\/strong><br \/>\nIn a meta-analysis, we found no evidence that higher intake of allium vegetables reduces risk for CRC. We observed that garlic supplements increase risk for CRC, but this finding requires external validation.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-59320","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"State Key Laboratory of Environment Health (Incubation), MOE (Ministry of Education) Key Laboratory of Environment &amp; Health, Ministry of Environmental Protection Key Laboratory of Environment and Health (Wuhan), and Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.\r\nrongzhong91@gmail.com","annee":"2014","mois":"3","numero":"12:12","page":"1991-2001","auteurs":[{"ID":1162,"post_author":"0","post_date":"2018-12-03 15:56:55","post_date_gmt":"2018-12-03 14:56:55","post_content":"","post_title":"Lu Qi","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lu-qi","to_ping":"","pinged":"","post_modified":"2018-12-03 15:56:55","post_modified_gmt":"2018-12-03 14:56:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/lu-qi\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":59316,"post_author":"0","post_date":"2018-12-04 08:20:50","post_date_gmt":"2018-12-04 07:20:50","post_content":"","post_title":"Beibei Zhu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"beibei-zhu","to_ping":"","pinged":"","post_modified":"2018-12-04 08:20:50","post_modified_gmt":"2018-12-04 07:20:50","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/beibei-zhu\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":59317,"post_author":"0","post_date":"2018-12-04 08:20:50","post_date_gmt":"2018-12-04 07:20:50","post_content":"","post_title":"Li Zou","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"li-zou","to_ping":"","pinged":"","post_modified":"2018-12-04 08:20:50","post_modified_gmt":"2018-12-04 07:20:50","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/li-zou\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":59318,"post_author":"0","post_date":"2018-12-04 08:20:51","post_date_gmt":"2018-12-04 07:20:51","post_content":"","post_title":"Rong Zhong","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"rong-zhong","to_ping":"","pinged":"","post_modified":"2018-12-04 08:20:51","post_modified_gmt":"2018-12-04 07:20:51","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/rong-zhong\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":59319,"post_author":"0","post_date":"2018-12-04 08:20:52","post_date_gmt":"2018-12-04 07:20:52","post_content":"","post_title":"Xiaoping Miao","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"xiaoping-miao","to_ping":"","pinged":"","post_modified":"2018-12-04 08:20:52","post_modified_gmt":"2018-12-04 07:20:52","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/xiaoping-miao\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":28068,"post_author":"0","post_date":"2018-12-03 23:01:45","post_date_gmt":"2018-12-03 22:01:45","post_content":"","post_title":"CLIN GASTROENTEROL HEPATOL","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"clin-gastroenterol-hepatol","to_ping":"","pinged":"","post_modified":"2018-12-03 23:01:45","post_modified_gmt":"2018-12-03 22:01:45","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/clin-gastroenterol-hepatol\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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