{"id":59257,"date":"2014-04-01T00:00:00","date_gmt":"2018-12-04T07:19:32","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/prepregnancy-low-carbohydrate-dietary-pattern-and-risk-of\/"},"modified":"2018-12-04T08:19:32","modified_gmt":"2018-12-04T07:19:32","slug":"prepregnancy-low-carbohydrate-dietary-pattern-and-risk-of","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/prepregnancy-low-carbohydrate-dietary-pattern-and-risk-of\/","title":{"rendered":"Prepregnancy low-carbohydrate dietary pattern and risk of gestational diabetes mellitus: a prospective cohort study."},"content":{"rendered":"

BACKGROUND<\/strong>
\nLow-carbohydrate diets (LCDs) have been vastly popular for weight loss. The association between a low-carbohydrate dietary pattern and risk of gestational diabetes mellitus (GDM) remains unknown.<\/p>\n

OBJECTIVE<\/strong>
\nWe aimed to prospectively examine the association of 3 prepregnancy low-carbohydrate dietary patterns with risk of GDM.<\/p>\n

DESIGN<\/strong>
\nWe included 21,411 singleton pregnancies in the Nurses' Health Study II. Prepregnancy LCD scores were calculated from validated food-frequency questionnaires, including an overall LCD score on the basis of intakes of carbohydrate, total protein, and total fat; an animal LCD score on the basis of intakes of carbohydrate, animal protein, and animal fat; and a vegetable LCD score on the basis of intakes of carbohydrate, vegetable protein, and vegetable fat. A higher score reflected a higher intake of fat and protein and a lower intake of carbohydrate, and it indicated closer adherence to a low-carbohydrate dietary pattern. RRs and 95% CIs were estimated by using generalized estimating equations with log-binomial models.<\/p>\n

RESULTS<\/strong>
\nWe documented 867 incident GDM pregnancies during 10 y follow-up. Multivariable-adjusted RRs (95% CIs) of GDM for comparisons of highest with lowest quartiles were 1.27 (1.06, 1.51) for the overall LCD score (P-trend = 0.03), 1.36 (1.13, 1.64) for the animal LCD score (P-trend = 0.003), and 0.84 (0.69, 1.03) for the vegetable LCD score (P-trend = 0.08). Associations between LCD scores and GDM risk were not significantly modified by age, parity, family history of diabetes, physical activity, or overweight status.<\/p>\n

CONCLUSIONS<\/strong>
\nA prepregnancy low-carbohydrate dietary pattern with high protein and fat from animal-food sources is positively associated with GDM risk, whereas a prepregnancy low-carbohydrate dietary pattern with high protein and fat from vegetable food sources is not associated with the risk. Women of reproductive age who follow a low-carbohydrate dietary pattern may consider consuming vegetable rather than animal sources of protein and fat to minimize their risk of GDM.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-59257","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Rockville, MD (WB, MK, and CZ); the Division of Biostatistics and Epidemiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH (KB); the Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA (DKT and JC); the Centre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark (SFO); the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (JC); and the Department of Endocrinology, Rigshospitalet, Copenhagen, Denmark (AV).\r\nwei.bao@nih.gov","annee":"2014","mois":"4","numero":"99:6","page":"1378-84","auteurs":[{"ID":22493,"post_author":"0","post_date":"2018-12-03 21:05:38","post_date_gmt":"2018-12-03 20:05:38","post_content":"","post_title":"Wei Bao","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"wei-bao","to_ping":"","pinged":"","post_modified":"2018-12-03 21:05:38","post_modified_gmt":"2018-12-03 20:05:38","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/wei-bao\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":59255,"post_author":"0","post_date":"2018-12-04 08:19:30","post_date_gmt":"2018-12-04 07:19:30","post_content":"","post_title":"Katherine 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