{"id":58972,"date":"2014-04-01T00:00:00","date_gmt":"2018-12-04T07:14:22","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-effects-of-a-mediterranean-diet-on-need-for-diabetes-drugs\/"},"modified":"2018-12-04T08:14:22","modified_gmt":"2018-12-04T07:14:22","slug":"the-effects-of-a-mediterranean-diet-on-need-for-diabetes-drugs","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-effects-of-a-mediterranean-diet-on-need-for-diabetes-drugs\/","title":{"rendered":"The Effects of a Mediterranean Diet on Need for Diabetes Drugs and Remission of Newly Diagnosed Type 2 Diabetes: Follow-up of a Randomized Trial."},"content":{"rendered":"<p><strong>OBJECTIVE:<\/strong><\/p>\n<p>To assess the long-term effects of dietary interventions on glycemic control, need for diabetes medications, and remission of type 2 diabetes.<\/p>\n<p><strong>RESEARCH DESIGN AND METHODS:<\/strong><\/p>\n<p>Originally, in a two-arm trial design, overweight, middle-aged men and women with newly diagnosed type 2 diabetes were randomized to a low-carbohydrate Mediterranean diet (LCMD; n = 108) or a low-fat diet (n = 107). After 4 years, participants who were still free of diabetes medications were further followed up until the primary end point (need of a diabetic drug); remission of diabetes (partial or complete) and changes in weight, glycemic control, and cardiovascular risk factors were also evaluated.<\/p>\n<p><strong>RESULTS:<\/strong><\/p>\n<p>The primary end point was reached in all participants after a total follow-up of 6.1 years in the low-fat group and 8.1 years in the LCMD group; median survival time was 2.8 years (95% CI 2.4-3.2) and 4.8 years (4.3-5.2), respectively. The unadjusted hazard ratio for the overall follow-up was 0.68 (0.50-0.89; P &lt; 0.001). LCMD participants were more likely to experience any remission (partial or complete), with a prevalence of 14.7% (13.0-16.5%) during the first year and 5.0% (4.4-5.6%) during year 6 compared with 4.1% (3.1-5.0%) at year 1 and 0% at year 6 in the low-fat diet group.<\/p>\n<p><strong>CONCLUSIONS:<\/strong><\/p>\n<p>In patients with newly diagnosed type 2 diabetes, an LCMD resulted in a greater reduction of HbA1c levels, higher rate of diabetes remission, and delayed need for diabetes medication compared with a low-fat diet.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-58972","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Diabetes Unit, University Hospital at the Second University of Naples, Naples, Italy.\r\nkatherine.esposito@unina2.it","annee":"2014","mois":"4","numero":"37:7","page":"1824-30","auteurs":[{"ID":9279,"post_author":"0","post_date":"2018-12-03 18:09:23","post_date_gmt":"2018-12-03 17:09:23","post_content":"","post_title":"Katherine Esposito","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"katherine-esposito","to_ping":"","pinged":"","post_modified":"2018-12-03 18:09:23","post_modified_gmt":"2018-12-03 17:09:23","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/katherine-esposito\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9280,"post_author":"0","post_date":"2018-12-03 18:09:24","post_date_gmt":"2018-12-03 17:09:24","post_content":"","post_title":"Dario Giugliano","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"dario-giugliano","to_ping":"","pinged":"","post_modified":"2018-12-03 18:09:24","post_modified_gmt":"2018-12-03 17:09:24","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/dario-giugliano\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9283,"post_author":"0","post_date":"2018-12-03 18:09:26","post_date_gmt":"2018-12-03 17:09:26","post_content":"","post_title":"Maria Ida Maiorino","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"maria-ida-maiorino","to_ping":"","pinged":"","post_modified":"2018-12-03 18:09:26","post_modified_gmt":"2018-12-03 17:09:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/maria-ida-maiorino\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":58971,"post_author":"0","post_date":"2018-12-04 08:14:21","post_date_gmt":"2018-12-04 07:14:21","post_content":"","post_title":"Michela Petrizzo","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"michela-petrizzo","to_ping":"","pinged":"","post_modified":"2018-12-04 08:14:21","post_modified_gmt":"2018-12-04 07:14:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/michela-petrizzo\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":16661,"post_author":"0","post_date":"2018-12-03 19:41:47","post_date_gmt":"2018-12-03 18:41:47","post_content":"","post_title":"Giuseppe Bellastella","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"giuseppe-bellastella","to_ping":"","pinged":"","post_modified":"2018-12-03 19:41:47","post_modified_gmt":"2018-12-03 18:41:47","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/giuseppe-bellastella\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":16521,"post_author":"0","post_date":"2018-12-03 19:40:05","post_date_gmt":"2018-12-03 18:40:05","post_content":"","post_title":"Diabetes care","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"diabetes-care","to_ping":"","pinged":"","post_modified":"2018-12-03 19:40:05","post_modified_gmt":"2018-12-03 18:40:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/diabetes-care\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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