{"id":58964,"date":"2014-04-01T00:00:00","date_gmt":"2018-12-04T07:14:13","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/how-does-the-mediterranean-diet-promote-cardiovascular-health\/"},"modified":"2018-12-04T08:14:13","modified_gmt":"2018-12-04T07:14:13","slug":"how-does-the-mediterranean-diet-promote-cardiovascular-health","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/how-does-the-mediterranean-diet-promote-cardiovascular-health\/","title":{"rendered":"How does the Mediterranean diet promote cardiovascular health? Current progress toward molecular mechanisms: Gene-diet interactions at the genomic, transcriptomic, and epigenomic levels provide novel insights into new mechanisms."},"content":{"rendered":"<p>Epidemiological evidence supports a health-promoting effect of the Mediterranean Diet (MedDiet), especially in the prevention of cardiovascular diseases. These cardiovascular benefits have been attributed to a number of components of the MedDiet such as monounsaturated fatty acids, antioxidant vitamins and phytochemicals. However, the underlying mechanisms remain unknown. Likewise, little is known about the genes that define inter-individual variation in response to the MedDiet, although the TCF7L2 gene is emerging as an illustrative candidate for determining relative risk of cardiovascular events in response to the MedDiet. Moreover, omics technologies are providing evidence supporting potential mechanisms, some of them implicating epigenetics (i.e. microRNAs, methylation), and certain data suggest that some traditional foods could contribute via microRNAs possibly acting as exogenous regulators of gene expression. Future research should aim at increasing and consolidating the nutrigenetic and nutrigenomic knowledge of the MedDiet in order to provide sound, personalized and optimized nutritional recommendations.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-58964","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Preventive Medicine and Public Health, School of Medicine, University of Valencia, Valencia, Spain; CIBER Fisiopatolog\u00eda de la Obesidad y Nutrici\u00f3n, Instituto de Salud Carlos III, Madrid, Spain\r\ndolores.corella@uv.es","annee":"2014","mois":"4","numero":"36:5","page":"526-37","auteurs":[{"ID":27322,"post_author":"0","post_date":"2018-12-03 22:51:18","post_date_gmt":"2018-12-03 21:51:18","post_content":"","post_title":"Dolores Corella D","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"dolores-corella-d","to_ping":"","pinged":"","post_modified":"2018-12-03 22:51:18","post_modified_gmt":"2018-12-03 21:51:18","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/dolores-corella-d\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":58962,"post_author":"0","post_date":"2018-12-04 08:14:12","post_date_gmt":"2018-12-04 07:14:12","post_content":"","post_title":"JM Ordovas","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jm-ordovas","to_ping":"","pinged":"","post_modified":"2018-12-04 08:14:12","post_modified_gmt":"2018-12-04 07:14:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jm-ordovas\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":58963,"post_author":"0","post_date":"2018-12-04 08:14:12","post_date_gmt":"2018-12-04 07:14:12","post_content":"","post_title":"BioEssays : news and reviews in molecular, cellular and developmental biology","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"bioessays-news-and-reviews-in-molecular-cellular-and-developmental-biology","to_ping":"","pinged":"","post_modified":"2018-12-04 08:14:12","post_modified_gmt":"2018-12-04 07:14:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/bioessays-news-and-reviews-in-molecular-cellular-and-developmental-biology\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>How does the Mediterranean diet promote cardiovascular health? 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