{"id":58493,"date":"1999-06-01T00:00:00","date_gmt":"2018-12-04T07:00:04","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/long-term-intake-of-dietary-fiber-and-decreased-risk-of-coronary\/"},"modified":"2018-12-04T08:00:04","modified_gmt":"2018-12-04T07:00:04","slug":"long-term-intake-of-dietary-fiber-and-decreased-risk-of-coronary","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/long-term-intake-of-dietary-fiber-and-decreased-risk-of-coronary\/","title":{"rendered":"Long-term intake of dietary fiber and decreased risk of coronary heart disease among women"},"content":{"rendered":"<p>CONTEXT: Epidemiological studies of men suggest that dietary fiber intake protects against coronary heart disease (CHD), but data on this association in women are sparse.<\/p>\n<p>OBJECTIVE: To examine the association between long-term intake of total dietary fiber as well as fiber from different sources and risk of CHD in women.<\/p>\n<p>DESIGN AND SETTING: The Nurses&#039; Health Study, a large, prospective cohort study of US women followed up for 10 years from 1984. Dietary data were collected in 1984, 1986, and 1990, using a validated semiquantitative food frequency questionnaire.<\/p>\n<p>PARTICIPANTS: A total of 68782 women aged 37 to 64 years without previously diagnosed angina, myocardial infarction (MI), stroke, cancer, hypercholesterolemia, or diabetes at baseline.<\/p>\n<p>MAIN OUTCOME MEASURE: Incidence of acute MI or death due to CHD by amount of fiber intake.<\/p>\n<p>RESULTS: Response rate averaged 80% to 90% during the 10-year follow-up. We documented 591 major CHD events (429 nonfatal MIs and 162 CHD deaths). The age-adjusted relative risk (RR) for major CHD events was 0.53 (95% confidence interval [CI], 0.40-0.69) for women in the highest quintile of total dietary fiber intake (median, 22.9 g\/d) compared with women in the lowest quintile (median, 11.5 g\/d). After controlling for age, cardiovascular risk factors, dietary factors, and multivitamin supplement use, the RR was 0.77 (95% CI, 0.57-1.04). For a 10-g\/d increase in total fiber intake (the difference between the lowest and highest quintiles), the multivariate RR of total CHD events was 0.81 (95% CI, 0.66-0.99). Among different sources of dietary fiber (eg, cereal, vegetables, fruit), only cereal fiber was strongly associated with a reduced risk of CHD (multivariate RR, 0.63; 95% CI, 0.49-0.81 for each 5-g\/d increase in cereal fiber).<\/p>\n<p>CONCLUSIONS: Our findings in women support the hypothesis that higher fiber intake, particularly from cereal sources, reduces the risk of CHD.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-58493","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden. alicja.wolk@mep.ki.se","annee":"1999","mois":"6","numero":"281:21","page":"1998-2004","auteurs":[{"ID":5255,"post_author":"0","post_date":"2018-12-03 17:25:59","post_date_gmt":"2018-12-03 16:25:59","post_content":"","post_title":"Alicja 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05:15:18","post_content":"","post_title":"Speizer","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"speizer-2","to_ping":"","pinged":"","post_modified":"2018-12-04 06:15:18","post_modified_gmt":"2018-12-04 05:15:18","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/speizer-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":57138,"post_author":"0","post_date":"2018-12-04 07:34:47","post_date_gmt":"2018-12-04 06:34:47","post_content":"","post_title":"Hennekens","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hennekens","to_ping":"","pinged":"","post_modified":"2018-12-04 07:34:47","post_modified_gmt":"2018-12-04 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