{"id":58431,"date":"1999-06-01T00:00:00","date_gmt":"2018-12-04T06:57:50","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/combined-effect-of-vegetable-protein-soy-and-soluble-fiber\/"},"modified":"2018-12-04T07:57:50","modified_gmt":"2018-12-04T06:57:50","slug":"combined-effect-of-vegetable-protein-soy-and-soluble-fiber","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/combined-effect-of-vegetable-protein-soy-and-soluble-fiber\/","title":{"rendered":"Combined effect of vegetable protein (soy) and soluble fiber added to a standard cholesterol-lowering diet"},"content":{"rendered":"<p>Dietary treatment of hyperlipidemia focuses on reducing saturated fat and dietary cholesterol. Other aspects of diet are not emphasized at present, despite growing evidence that a number of plant components decrease serum cholesterol. We therefore determined whether a combination of two plant components, vegetable protein and soluble fiber, further reduce serum lipids when incorporated into the currently advocated low-saturated-fat diet. Thirty-one hyperlipidemic men and women ate two 1-month low-fat (&lt;7% of total energy from saturated fat), low-cholesterol (&lt;80 mg cholesterol\/d) metabolic diets in a randomized crossover study. The major differences between test and control diets were an increased amount of vegetable protein (93% v 23% of total protein), of which 33 g\/d was soy, and a doubling of soluble fiber. Fasting blood samples were obtained at the start and end of each phase. On the last 3 days of each phase, fecal collections were obtained. Compared with the low-fat control diet, the test diet decreased total cholesterol (6.2% +\/- 1.2%, P &lt; .001), low-density lipoprotein (LDL) cholesterol (6.7% +\/- 1.7%, P &lt; .001), apolipoprotein B (8.2% +\/- 1.2%, P &lt; .001), and the ratios of LDL to high-density lipoprotein (HDL) cholesterol (6.3% +\/- 2.0%, P = .004) and apolipoprotein B to A-I (5.4% +\/- 1.5%, P = .001). A combination of vegetable protein and soluble fiber significantly improved the lipid-lowering effect of a low-saturated-fat diet. The results support expanding the current dietary advice to include increased vegetable protein and soluble fiber intake so that the gap in effectiveness between a good diet and drug therapy is reduced.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-58431","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Clinical Nutrition and Risk Factor Modification Center and the Department of Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.","annee":"1999","mois":"6","numero":"48:6","page":"809-816","auteurs":[{"ID":44228,"post_author":"0","post_date":"2018-12-04 03:19:52","post_date_gmt":"2018-12-04 02:19:52","post_content":"","post_title":"Jenkins","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jenkins","to_ping":"","pinged":"","post_modified":"2018-12-04 03:19:52","post_modified_gmt":"2018-12-04 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