{"id":57376,"date":"2000-01-01T00:00:00","date_gmt":"2018-12-04T06:38:23","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/inhibition-of-azoxymethane-induced-colon-cancer-by-orange\/"},"modified":"2018-12-04T07:38:23","modified_gmt":"2018-12-04T06:38:23","slug":"inhibition-of-azoxymethane-induced-colon-cancer-by-orange","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/inhibition-of-azoxymethane-induced-colon-cancer-by-orange\/","title":{"rendered":"Inhibition of azoxymethane-induced colon cancer by orange juice"},"content":{"rendered":"

Previous research has shown that hesperidin, a flavanone glycoside in orange juice, inhibits colon carcinogenesis and that feeding double-strength orange juice delays the onset of chemically induced mammary cancer in rats. This study determined whether feeding single-strength, pasteurized orange juice would inhibit azoxymethane (AOM)-induced colon cancer in male Fischer 344 rats. Colon cancer was initiated by injecting AOM (15 mg\/kg body wt) at 22 and 29 days of age. One week after the second AOM injection, orange juice replaced drinking water for the experimental group (n = 30). The rats were killed 28 weeks later, and tumors were removed for histological analysis. Feeding orange juice reduced tumor incidence by 22% (p < 0.05). Tumor reduction was associated with a decreased labeling index and proliferation zone in the colonic mucosa. Hesperidin, other flavonoids, limonin 17-beta-D-glucopyranoside, and other limonoid glucosides are potential chemopreventive agents in orange juice that could account for the decreased colon tumorigenesis associated with feeding orange juice<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-57376","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Michigan State University, Lansing 48824-1224, USA","annee":"2000","mois":"0","numero":"36:2","page":"224-229","auteurs":[{"ID":57372,"post_author":"0","post_date":"2018-12-04 07:38:21","post_date_gmt":"2018-12-04 06:38:21","post_content":"","post_title":"Bennink","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"bennink","to_ping":"","pinged":"","post_modified":"2018-12-04 07:38:21","post_modified_gmt":"2018-12-04 06:38:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/bennink\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":57373,"post_author":"0","post_date":"2018-12-04 07:38:22","post_date_gmt":"2018-12-04 06:38:22","post_content":"","post_title":"Chee","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"chee","to_ping":"","pinged":"","post_modified":"2018-12-04 07:38:22","post_modified_gmt":"2018-12-04 06:38:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/chee\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":57374,"post_author":"0","post_date":"2018-12-04 07:38:22","post_date_gmt":"2018-12-04 06:38:22","post_content":"","post_title":"Miyagi","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"miyagi","to_ping":"","pinged":"","post_modified":"2018-12-04 07:38:22","post_modified_gmt":"2018-12-04 06:38:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/miyagi\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":57375,"post_author":"0","post_date":"2018-12-04 07:38:23","post_date_gmt":"2018-12-04 06:38:23","post_content":"","post_title":"Om","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"om","to_ping":"","pinged":"","post_modified":"2018-12-04 07:38:23","post_modified_gmt":"2018-12-04 06:38:23","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/om\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1760,"post_author":"0","post_date":"2018-12-03 16:02:19","post_date_gmt":"2018-12-03 15:02:19","post_content":"","post_title":"Nutrition and cancer","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"nutrition-and-cancer","to_ping":"","pinged":"","post_modified":"2018-12-03 16:02:19","post_modified_gmt":"2018-12-03 15:02:19","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/nutrition-and-cancer\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nInhibition of azoxymethane-induced colon cancer by orange juice - 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