{"id":57360,"date":"2000-06-01T00:00:00","date_gmt":"2018-12-04T06:38:09","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/lipoprotein-carotenoid-profiles-and-the-susceptibility-of\/"},"modified":"2018-12-04T07:38:09","modified_gmt":"2018-12-04T06:38:09","slug":"lipoprotein-carotenoid-profiles-and-the-susceptibility-of","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/lipoprotein-carotenoid-profiles-and-the-susceptibility-of\/","title":{"rendered":"Lipoprotein carotenoid profiles and the susceptibility of low density lipoprotein to oxidative modification in healthy elderly volunteers"},"content":{"rendered":"

Objectives: <\/strong>
\nTo determine antioxidant levels in plasma, low density lipoprotein (LDL) and high density Lipoprotein (HDL) before and after supplementation with a carotene mixture or lycopene; to examine the interrelationships between carotenoids and tocopherols in plasma, LDL and HDL under normal dietary conditions and after supplementation with carotene or lycopene; and to investigate whether supplementation with a carotene mixture or lycopene could enhance the ability of LDL to withstand oxidative stress in vitro, in a group of healthy elderly people aged greater than or equal to 65 y.<\/p>\n

Design: <\/strong>
\nRandomized placebo controlled double blind study.<\/p>\n

Setting: <\/strong>
\nFree living urban adults in ireland.Subjects: Fifty-one volunteers aged greater than or equal to 65 y.Interventions: Volunteers were each provided with capsules providing either 13.3 mg lycopene, or 11.9 mg carotene or placebo for 12 weeks.<\/p>\n

Results: <\/strong>
\nBoth absolute and cholesterol standardized plasma carotenoid concentrations correlated strongly with LDL and HDL concentrations of carotenoids before and after supplementation with carotene or lycopene. Supplementation with a carotene mixture or lycopene had no effect on oxidative modification of LDL in vitro despite significant increases in plasma and LDL concentrations of lycopene, alpha-carotene and beta-carotene.<\/p>\n

Conclusions: <\/strong>
\nThe results of this study suggest that, in unsupplemented individuals, plasma can act as a biomarker of carotenoid and gamma-tocopherol concentrations in both LDL and HDL. Supplementation with carotenes or lycopene do not reduce or delay oxidation of LDL. These results support the assumption that carotenoids, such as beta-carotene and lycopene, may show protective effects because they are good markers of fruit and vegetable intake.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-57360","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"MORRISSEY PA,NATL UNIV IRELAND UNIV COLL CORK,DEPT FOOD SCI & TECHNOL DIV NUTR SCI;CORK, IRELAND.p.morrissey@ucc.ie","annee":"2000","mois":"6","numero":"54:6","page":"500-507","auteurs":[{"ID":57357,"post_author":"0","post_date":"2018-12-04 07:38:08","post_date_gmt":"2018-12-04 06:38:08","post_content":"","post_title":"Carroll","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"carroll-3","to_ping":"","pinged":"","post_modified":"2018-12-04 07:38:08","post_modified_gmt":"2018-12-04 06:38:08","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/carroll-3\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":57358,"post_author":"0","post_date":"2018-12-04 07:38:08","post_date_gmt":"2018-12-04 06:38:08","post_content":"","post_title":"Corridan","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"corridan-2","to_ping":"","pinged":"","post_modified":"2018-12-04 07:38:08","post_modified_gmt":"2018-12-04 06:38:08","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/corridan-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":57359,"post_author":"0","post_date":"2018-12-04 07:38:09","post_date_gmt":"2018-12-04 06:38:09","post_content":"","post_title":"Morrissey","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"morrissey","to_ping":"","pinged":"","post_modified":"2018-12-04 07:38:09","post_modified_gmt":"2018-12-04 06:38:09","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/morrissey\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1262,"post_author":"0","post_date":"2018-12-03 15:57:47","post_date_gmt":"2018-12-03 14:57:47","post_content":"","post_title":"European journal of clinical nutrition","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"european-journal-of-clinical-nutrition","to_ping":"","pinged":"","post_modified":"2018-12-03 15:57:47","post_modified_gmt":"2018-12-03 14:57:47","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/european-journal-of-clinical-nutrition\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nLipoprotein carotenoid profiles and the susceptibility of low density lipoprotein to oxidative modification in healthy elderly volunteers - 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