{"id":57146,"date":"2000-10-01T00:00:00","date_gmt":"2018-12-04T06:34:54","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/profiles-of-a-healthful-diet-and-its-relationship-to-biomarkers\/"},"modified":"2018-12-04T07:34:54","modified_gmt":"2018-12-04T06:34:54","slug":"profiles-of-a-healthful-diet-and-its-relationship-to-biomarkers","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/profiles-of-a-healthful-diet-and-its-relationship-to-biomarkers\/","title":{"rendered":"Profiles of a healthful diet and its relationship to biomarkers in a population sample from Mediterranean southern France"},"content":{"rendered":"<p>OBJECTIVES:<br \/>\nThe failure of single-nutrient supplementation to prevent disease in intervention studies underlines the necessity to develop a holistic view of food intake. The objectives of this study were to devise a diet quality index (DQI) and identify biomarkers of multidimensional dietary behavior.<\/p>\n<p>DESIGN:<br \/>\nA nutrition survey was conducted in Mediterranean southern France by means of a food frequency questionnaire. The DQI was based on current dietary recommendations for prevention of diet-related diseases such as cardiovascular disease and some cancers. A second DQI included tobacco use.<\/p>\n<p>STATISTICAL ANALYSES:<br \/>\nPerformed Spearman rank correlations, cross-classifications and intraclass correlations were computed between the DQI and biomarkers.<\/p>\n<p>RESULTS:<br \/>\nOf the 146 subjects, 10 had a healthful diet and 18 had a poor diet. Erythrocyte omega-3 fatty acids-eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)-beta carotene, and vitamin E concentrations were lower and cholesterol concentrations were higher in the poor diet; the difference was significant for EPA and DHA and borderline significant for vitamin E. Significant correlation was found between the DQI and vitamin E (-0.12), EPA (-0.30), and DHA (-0.28), and beta carotene (-0.17) when tobacco use was considered, but not between the DQI and cholesterol. The correlation coefficient reached 0.58 (P0.01) for a composite index based on all biomarkers except cholesterol.<\/p>\n<p>CONCLUSIONS:<br \/>\nSubjects with a beta carotene levels greater thanl &micro;mol\/L, vitamin E greater than 30 &micro;mol\/L and EPA greater than 0.65% and DHA greater than 4% of fatty acids in erythrocytes were likely to have a healthful diet. Each biomarker indicated the quality of diet, but correlation was higher with a composite index.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-57146","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Groupe d'Epidemiologie Metabolique, Centre de Recherche en Cancerologie, Montpellier, France.","annee":"2000","mois":"10","numero":"100:10","page":"1164-1161","auteurs":[{"ID":19041,"post_author":"0","post_date":"2018-12-03 20:15:54","post_date_gmt":"2018-12-03 19:15:54","post_content":"","post_title":"J Dallongeville","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-dallongeville","to_ping":"","pinged":"","post_modified":"2018-12-03 20:15:54","post_modified_gmt":"2018-12-03 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06:34:53","post_content":"","post_title":"Romon","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"romon","to_ping":"","pinged":"","post_modified":"2018-12-04 07:34:53","post_modified_gmt":"2018-12-04 06:34:53","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/romon\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":57145,"post_author":"0","post_date":"2018-12-04 07:34:53","post_date_gmt":"2018-12-04 06:34:53","post_content":"","post_title":"Scali","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"scali","to_ping":"","pinged":"","post_modified":"2018-12-04 07:34:53","post_modified_gmt":"2018-12-04 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