{"id":56667,"date":"2000-10-01T00:00:00","date_gmt":"2018-12-04T06:26:55","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/intake-of-flavonoids-carotenoids-vitamins-c-and-e-and-risk\/"},"modified":"2018-12-04T07:26:55","modified_gmt":"2018-12-04T06:26:55","slug":"intake-of-flavonoids-carotenoids-vitamins-c-and-e-and-risk","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/intake-of-flavonoids-carotenoids-vitamins-c-and-e-and-risk\/","title":{"rendered":"Intake of flavonoids, carotenoids, vitamins C and E, and risk of stroke in male smokers"},"content":{"rendered":"<p><strong>BACKGROUND AND PURPOSE:<\/strong><br \/>\nAntioxidants may protect against atherosclerosis and thus prevent cerebrovascular disease. We studied the association between dietary antioxidants and subtypes of stroke.<\/p>\n<p><strong>METHODS:<\/strong><br \/>\nThe study cohort consisted of 26 593 male smokers, aged 50 to 69 years, without a history of stroke. They were participants of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study in Finland. The men completed a validated dietary questionnaire at baseline. Incident cases were identified through national registers.<\/p>\n<p><strong>RESULTS:<\/strong><br \/>\nDuring a 6.1-year follow-up, 736 cerebral infarctions, 83 subarachnoid hemorrhages, and 95 intracerebral hemorrhages occurred. Neither dietary flavonols and flavones nor vitamin E were associated with risk for stroke. The dietary intake of beta-carotene was inversely associated with the risk for cerebral infarction (relative risk [RR] of highest versus lowest quartile 0.74, 95% CI 0.60 to 0. 91), lutein plus zeaxanthin with risk for subarachnoid hemorrhage (RR 0.47, 95% CI 0.24 to 0.93), and lycopene with risks of cerebral infarction (RR 0.74, 95% CI 0.59 to 0.92) and intracerebral hemorrhage (RR 0.45, 95% CI 0.24 to 0.86). Vitamin C intake was inversely associated with the risk for intracerebral hemorrhage (RR 0.39, 95% CI 0.21 to 0.74). After simultaneous modeling of the antioxidants, a significant association remained only between beta-carotene intake and risk for cerebral infarction (RR 0.77, 95% CI 0.61 to 0.99).<\/p>\n<p><strong>CONCLUSIONS:<\/strong><br \/>\nDietary intake of beta-carotene was inversely associated with the risk for cerebral infarction. No association was detected between other dietary antioxidants and risk for stroke.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-56667","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"\"HIRVONEN T,NATL PUBL HLTH INST,DEPT NUTR; FINLAND.\"","annee":"2000","mois":"10","numero":"31:10","page":"2301-2306","auteurs":[{"ID":14420,"post_author":"0","post_date":"2018-12-03 19:09:30","post_date_gmt":"2018-12-03 18:09:30","post_content":"","post_title":"Demetrius Albanes","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"demetrius-albanes","to_ping":"","pinged":"","post_modified":"2018-12-03 19:09:30","post_modified_gmt":"2018-12-03 18:09:30","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/demetrius-albanes\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":40791,"post_author":"0","post_date":"2018-12-04 02:21:40","post_date_gmt":"2018-12-04 01:21:40","post_content":"","post_title":"Pietinen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"pietinen","to_ping":"","pinged":"","post_modified":"2018-12-04 02:21:40","post_modified_gmt":"2018-12-04 01:21:40","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/pietinen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":28894,"post_author":"0","post_date":"2018-12-03 23:11:57","post_date_gmt":"2018-12-03 22:11:57","post_content":"","post_title":"Jarmo Virtamo","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jarmo-virtamo","to_ping":"","pinged":"","post_modified":"2018-12-03 23:11:57","post_modified_gmt":"2018-12-03 22:11:57","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jarmo-virtamo\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":38482,"post_author":"0","post_date":"2018-12-04 01:38:04","post_date_gmt":"2018-12-04 00:38:04","post_content":"","post_title":"Hirvonen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hirvonen","to_ping":"","pinged":"","post_modified":"2018-12-04 01:38:04","post_modified_gmt":"2018-12-04 00:38:04","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hirvonen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":56666,"post_author":"0","post_date":"2018-12-04 07:26:55","post_date_gmt":"2018-12-04 06:26:55","post_content":"","post_title":"Korhonen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"korhonen","to_ping":"","pinged":"","post_modified":"2018-12-04 07:26:55","post_modified_gmt":"2018-12-04 06:26:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/korhonen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":14930,"post_author":"0","post_date":"2018-12-03 19:15:30","post_date_gmt":"2018-12-03 18:15:30","post_content":"","post_title":"STROKE","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"stroke","to_ping":"","pinged":"","post_modified":"2018-12-03 19:15:30","post_modified_gmt":"2018-12-03 18:15:30","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/stroke\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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