{"id":56184,"date":"2001-10-01T00:00:00","date_gmt":"2018-12-04T06:12:31","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/two-novel-cucurbitacins-neocucurbitacins-a-and-b-from-the\/"},"modified":"2018-12-04T07:12:31","modified_gmt":"2018-12-04T06:12:31","slug":"two-novel-cucurbitacins-neocucurbitacins-a-and-b-from-the","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/two-novel-cucurbitacins-neocucurbitacins-a-and-b-from-the\/","title":{"rendered":"Two novel cucurbitacins, neocucurbitacins A and B, from the Brazilian folk medicine \u00ab\u00a0Buchinha\u00a0\u00bb (Luffa operculata) and their effect on PEBP2alphaA and OCIF gene expression in a human osteoblast-like Saos-2 cell line."},"content":{"rendered":"<p style=\"text-align: justify\">Two novel cucurbitacins designated as neocucurbitacins A (1), possessing inhibitory activity of polyoma enhancer binding protein 2 alphaA (PEBP2 alphaA) and osteoclastogenesis-inhibitory factor (OCIF) gene expression in human osteoblast-like cells, and B (2) were isolated from the fruit of Luffa operculata. Their structures have been determined by extensive spectroscopic investigation.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-56184","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"KAWAHARA N,NATL INST HLTH SCI,SETAGAYA KU;1-18-1 KAMIYOGA; TOKYO 1588501, JAPAN.kawahara@nihs.go.jp","annee":"2001","mois":"10","numero":"49:10","page":"1377-1379","auteurs":[{"ID":56179,"post_author":"0","post_date":"2018-12-04 07:12:25","post_date_gmt":"2018-12-04 06:12:25","post_content":"","post_title":"Hakamatsuka","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hakamatsuka","to_ping":"","pinged":"","post_modified":"2018-12-04 07:12:25","post_modified_gmt":"2018-12-04 06:12:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hakamatsuka\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":56180,"post_author":"0","post_date":"2018-12-04 07:12:27","post_date_gmt":"2018-12-04 06:12:27","post_content":"","post_title":"Kawahara","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"kawahara","to_ping":"","pinged":"","post_modified":"2018-12-04 07:12:27","post_modified_gmt":"2018-12-04 06:12:27","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/kawahara\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":56181,"post_author":"0","post_date":"2018-12-04 07:12:28","post_date_gmt":"2018-12-04 06:12:28","post_content":"","post_title":"Satake","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"satake","to_ping":"","pinged":"","post_modified":"2018-12-04 07:12:28","post_modified_gmt":"2018-12-04 06:12:28","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/satake\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":56182,"post_author":"0","post_date":"2018-12-04 07:12:30","post_date_gmt":"2018-12-04 06:12:30","post_content":"","post_title":"Sekita","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sekita","to_ping":"","pinged":"","post_modified":"2018-12-04 07:12:30","post_modified_gmt":"2018-12-04 06:12:30","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sekita\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50408,"post_author":"0","post_date":"2018-12-04 05:16:14","post_date_gmt":"2018-12-04 04:16:14","post_content":"","post_title":"Kurata","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"kurata","to_ping":"","pinged":"","post_modified":"2018-12-04 05:16:14","post_modified_gmt":"2018-12-04 04:16:14","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/kurata\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":56183,"post_author":"0","post_date":"2018-12-04 07:12:31","post_date_gmt":"2018-12-04 06:12:31","post_content":"","post_title":"CHEMICAL AND PHARMACEUTICAL BULLETIN","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"chemical-and-pharmaceutical-bulletin","to_ping":"","pinged":"","post_modified":"2018-12-04 07:12:31","post_modified_gmt":"2018-12-04 06:12:31","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/chemical-and-pharmaceutical-bulletin\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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