{"id":55972,"date":"2001-12-01T00:00:00","date_gmt":"2018-12-04T06:08:46","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-a-hydrogenated-form-of-vitamin-k-on-bone-formation\/"},"modified":"2018-12-04T07:08:46","modified_gmt":"2018-12-04T06:08:46","slug":"effects-of-a-hydrogenated-form-of-vitamin-k-on-bone-formation","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-a-hydrogenated-form-of-vitamin-k-on-bone-formation\/","title":{"rendered":"Effects of a hydrogenated form of vitamin K on bone formation and resorption"},"content":{"rendered":"

BACKGROUND:<\/strong>
\nHydrogenation of vegetable oils affects blood lipid and lipoprotein concentrations. However, little is known about the effects of hydrogenation on other components, such as vitamin K. Low phylloquinone (vitamin K1) intake is a potential risk factor for bone fracture, although the mechanisms of this are unknown.<\/p>\n

OBJECTIVE:<\/strong>
\nThe objective was to compare the biological effects of phylloquinone and its hydrogenated form, dihydrophylloquinone, on vitamin K status and markers of bone formation and resorption.<\/p>\n

DESIGN:<\/strong>
\nIn a randomized crossover study in a metabolic unit, 15 young adults were fed a phylloquinone-restricted diet (10 µg\/d) for 15 d followed by 10 d of repletion (200 µg\/d) with either phylloquinone or dihydrophylloquinone.<\/p>\n

RESULTS:<\/strong>
\nThere was an increase and subsequent decrease in measures of bone formation (P = 0.002) and resorption (P = 0.08) after dietary phylloquinone restriction and repletion, respectively. In comparison with phylloquinone, dihydrophylloquinone was less absorbed and had no measurable biological effect on measures of bone formation and resorption.<\/p>\n

CONCLUSION:<\/strong>
\nHydrogenation of plant oils appears to decrease the absorption and biological effect of vitamin K in bone.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-55972","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"\"BOOTH SL,TUFTS UNIV,USDA HUMAN NUTR RES CTR AGING;711 WASHINGTON ST; BOSTON MA 02111, USA.sbooth@hnrc.tufts.edu \"","annee":"2001","mois":"12","numero":"74:6","page":"783-790","auteurs":[{"ID":5203,"post_author":"0","post_date":"2018-12-03 17:25:26","post_date_gmt":"2018-12-03 16:25:26","post_content":"","post_title":"Alice H Lichtenstein","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"alice-h-lichtenstein","to_ping":"","pinged":"","post_modified":"2018-12-03 17:25:26","post_modified_gmt":"2018-12-03 16:25:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/alice-h-lichtenstein\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":8439,"post_author":"0","post_date":"2018-12-03 18:00:12","post_date_gmt":"2018-12-03 17:00:12","post_content":"","post_title":"Sarah L Booth","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sarah-l-booth","to_ping":"","pinged":"","post_modified":"2018-12-03 18:00:12","post_modified_gmt":"2018-12-03 17:00:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sarah-l-booth\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":24675,"post_author":"0","post_date":"2018-12-03 21:59:54","post_date_gmt":"2018-12-03 20:59:54","post_content":"","post_title":"Nicola M McKeown","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"nicola-m-mckeown","to_ping":"","pinged":"","post_modified":"2018-12-03 21:59:54","post_modified_gmt":"2018-12-03 20:59:54","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/nicola-m-mckeown\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":55455,"post_author":"0","post_date":"2018-12-04 07:00:43","post_date_gmt":"2018-12-04 06:00:43","post_content":"","post_title":"Gundberg","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"gundberg","to_ping":"","pinged":"","post_modified":"2018-12-04 07:00:43","post_modified_gmt":"2018-12-04 06:00:43","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/gundberg\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":24050,"post_author":"0","post_date":"2018-12-03 21:44:29","post_date_gmt":"2018-12-03 20:44:29","post_content":"","post_title":"Edward Saltzman","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"edward-saltzman","to_ping":"","pinged":"","post_modified":"2018-12-03 21:44:29","post_modified_gmt":"2018-12-03 20:44:29","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/edward-saltzman\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":11078,"post_author":"0","post_date":"2018-12-03 18:30:56","post_date_gmt":"2018-12-03 17:30:56","post_content":"","post_title":"R J Silverwood","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"r-j-silverwood","to_ping":"","pinged":"","post_modified":"2018-12-03 18:30:56","post_modified_gmt":"2018-12-03 17:30:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/r-j-silverwood\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":44192,"post_author":"0","post_date":"2018-12-04 03:19:18","post_date_gmt":"2018-12-04 02:19:18","post_content":"","post_title":"AMERICAN JOURNAL OF CLINICAL NUTRITION","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"american-journal-of-clinical-nutrition","to_ping":"","pinged":"","post_modified":"2018-12-04 03:19:18","post_modified_gmt":"2018-12-04 02:19:18","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/american-journal-of-clinical-nutrition\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nEffects of a hydrogenated form of vitamin K on bone formation and resorption - 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