{"id":55876,"date":"2001-12-01T00:00:00","date_gmt":"2018-12-04T06:07:12","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/apple-favourably-affects-parameters-of-cholesterol-metabolism\/"},"modified":"2018-12-04T07:07:12","modified_gmt":"2018-12-04T06:07:12","slug":"apple-favourably-affects-parameters-of-cholesterol-metabolism","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/apple-favourably-affects-parameters-of-cholesterol-metabolism\/","title":{"rendered":"Apple favourably affects parameters of cholesterol metabolism and of anti-oxidative protection in cholesterol-fed rats"},"content":{"rendered":"<p style=\"text-align: justify\">The effects of apples on lipid metabolism were studied on 40 male Wistar rats adapted to semi-purified diets containing 0.3% cholesterol. In the experimental &#039;apple&#039; diet, a part of starch (15%) was replaced by lyophilized apple (Gala variety). In the control diet, 13% of carbohydrate was replaced by a mixture of fructose\/glucose\/saccharose to match the sugar supply from the apples. The lipid source was corn oil and the dietary supply of vitamin E was reduced to 1\/3 of the recommended value. The rats were sampled after 21 days adaptation. The fibre supply of the apple diet was notably low (about 2%); nevertheless, there was a slight but significant cholesterol-lowering effect in plasma, as well as in liver where cholesterol esters accumulate with cholesterol diets. The lipoprotein profile was markedly altered in apple-fed rats: a reduction of cholesterol in the triglyceride rich lipoprotein (TGRLP) fraction, together with a rise in the HDL fraction; hence there was a favourable effect in a cardiovascular protection perspective. This was paralleled by effects of the apple on cholesterol apparent absorption, which was markedly depressed, whereas bile acid digestive balance was unaffected. In parallel, there was a positive effect of the apple diet on parameters of oxidative stress prevention: higher FRAP plasma levels than in controls, together with a reduced MDA excretion in urine. In conclusion, the present work indicates that a moderate supply of dessert apples elicits interesting effects on lipid and peroxidation parameters.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-55876","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"DEMIGNE C,INRA,UNITE MALAD METAB & MICRONUTRIENTS CRNH AUVERGNE;F-63122 ST GENES CHAMPANELLE, FRANCE.demigne@clermont.inra.fr","annee":"2001","mois":"12","numero":"75:4","page":"445-452","auteurs":[{"ID":50781,"post_author":"0","post_date":"2018-12-04 05:23:59","post_date_gmt":"2018-12-04 04:23:59","post_content":"","post_title":"Aprikian","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"aprikian","to_ping":"","pinged":"","post_modified":"2018-12-04 05:23:59","post_modified_gmt":"2018-12-04 04:23:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/aprikian\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54897,"post_author":"0","post_date":"2018-12-04 06:52:00","post_date_gmt":"2018-12-04 05:52:00","post_content":"","post_title":"Besson","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"besson","to_ping":"","pinged":"","post_modified":"2018-12-04 06:52:00","post_modified_gmt":"2018-12-04 05:52:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/besson\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50782,"post_author":"0","post_date":"2018-12-04 05:24:01","post_date_gmt":"2018-12-04 04:24:01","post_content":"","post_title":"Busserolles","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"busserolles","to_ping":"","pinged":"","post_modified":"2018-12-04 05:24:01","post_modified_gmt":"2018-12-04 04:24:01","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/busserolles\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50783,"post_author":"0","post_date":"2018-12-04 05:24:02","post_date_gmt":"2018-12-04 04:24:02","post_content":"","post_title":"Demigne","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"demigne","to_ping":"","pinged":"","post_modified":"2018-12-04 05:24:02","post_modified_gmt":"2018-12-04 04:24:02","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/demigne\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":55875,"post_author":"0","post_date":"2018-12-04 07:07:11","post_date_gmt":"2018-12-04 06:07:11","post_content":"","post_title":"Levrat-verny","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"levrat-verny","to_ping":"","pinged":"","post_modified":"2018-12-04 07:07:11","post_modified_gmt":"2018-12-04 06:07:11","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/levrat-verny\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50179,"post_author":"0","post_date":"2018-12-04 05:12:14","post_date_gmt":"2018-12-04 04:12:14","post_content":"","post_title":"Remesy","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"remesy","to_ping":"","pinged":"","post_modified":"2018-12-04 05:12:14","post_modified_gmt":"2018-12-04 04:12:14","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/remesy\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":2399,"post_author":"0","post_date":"2018-12-03 16:55:16","post_date_gmt":"2018-12-03 15:55:16","post_content":"","post_title":"Food chemistry","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"food-chemistry","to_ping":"","pinged":"","post_modified":"2018-12-03 16:55:16","post_modified_gmt":"2018-12-03 15:55:16","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/food-chemistry\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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