{"id":55840,"date":"2002-01-01T00:00:00","date_gmt":"2018-12-04T06:06:40","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/"},"modified":"2018-12-04T07:06:40","modified_gmt":"2018-12-04T06:06:40","slug":"hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/","title":{"rendered":"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet"},"content":{"rendered":"<p>The present study examined the hypolipidemic activity of hawthorn fruit. New Zealand white rabbits were fed one of three diets, a reference diet with no cholesterol added (NC), a high cholesterol diet (1 g\/100 g, HC) and a HC diet supplemented with 2 g\/100 g hawthorn fruit powder (HC-H). After 12 wk, serum total cholesterol (TC) and triacylglycerols (TG) were 23.4 and 22.2% lower, respectively, in the hawthorn fruit group compared with the HC rabbits (P &lt; 0.05). Hawthorn supplementation led to 50.6% less cholesterol accumulation in aorta (P &lt; 0.05) and 23-95% greater excretion of neutral and acidic sterols (P &lt; 0.05). Supplementation of hawthorn fruit did not affect the activities of hepatic 3-hydroxy-3-methyl glutaryl coenzyme A reductase (HMG-CoA-R) or cholesterol 7alpha-hydroxylase (CH) but it suppressed the activity of intestinal acyl CoA:cholesterol acyltransferase (ACAT, P &lt; 0.05). The results suggest that the mechanism by which hawthorn fruit decreases serum cholesterol involves, at least in part, the inhibition of cholesterol absorption mediated by down-regulation of intestinal ACAT activity.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-55840","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"\"CHEN ZY,CHINESE UNIV HONG KONG,DEPT BIOCHEM; PEOPLES R CHINA.zhenyuchen@cuhk.edu.hk  \"","annee":"2002","mois":"1","numero":"132:1","page":"5-10","auteurs":[{"ID":41119,"post_author":"0","post_date":"2018-12-04 02:27:16","post_date_gmt":"2018-12-04 01:27:16","post_content":"","post_title":"Chen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"chen-8","to_ping":"","pinged":"","post_modified":"2018-12-04 02:27:16","post_modified_gmt":"2018-12-04 01:27:16","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/chen-8\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":55836,"post_author":"0","post_date":"2018-12-04 07:06:38","post_date_gmt":"2018-12-04 06:06:38","post_content":"","post_title":"Ho","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ho-2","to_ping":"","pinged":"","post_modified":"2018-12-04 07:06:38","post_modified_gmt":"2018-12-04 06:06:38","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ho-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":55759,"post_author":"0","post_date":"2018-12-04 07:05:27","post_date_gmt":"2018-12-04 06:05:27","post_content":"","post_title":"Huang","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"huang-9","to_ping":"","pinged":"","post_modified":"2018-12-04 07:05:27","post_modified_gmt":"2018-12-04 06:05:27","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/huang-9\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":55837,"post_author":"0","post_date":"2018-12-04 07:06:39","post_date_gmt":"2018-12-04 06:06:39","post_content":"","post_title":"James","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"james-4","to_ping":"","pinged":"","post_modified":"2018-12-04 07:06:39","post_modified_gmt":"2018-12-04 06:06:39","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/james-4\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":55838,"post_author":"0","post_date":"2018-12-04 07:06:39","post_date_gmt":"2018-12-04 06:06:39","post_content":"","post_title":"Lam","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lam-4","to_ping":"","pinged":"","post_modified":"2018-12-04 07:06:39","post_modified_gmt":"2018-12-04 06:06:39","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/lam-4\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":55839,"post_author":"0","post_date":"2018-12-04 07:06:40","post_date_gmt":"2018-12-04 06:06:40","post_content":"","post_title":"Zhang","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"zhang-7","to_ping":"","pinged":"","post_modified":"2018-12-04 07:06:40","post_modified_gmt":"2018-12-04 06:06:40","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/zhang-7\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":44294,"post_author":"0","post_date":"2018-12-04 03:21:12","post_date_gmt":"2018-12-04 02:21:12","post_content":"","post_title":"JOURNAL OF NUTRITION","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"journal-of-nutrition","to_ping":"","pinged":"","post_modified":"2018-12-04 03:21:12","post_modified_gmt":"2018-12-04 02:21:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/journal-of-nutrition\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet - Aprifel<\/title>\n<meta name=\"description\" content=\"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet\" \/>\n<meta property=\"og:description\" content=\"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/\",\"name\":\"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet - Aprifel\",\"isPartOf\":{\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\"},\"datePublished\":\"2018-12-04T06:06:40+00:00\",\"dateModified\":\"2018-12-04T06:06:40+00:00\",\"description\":\"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet - Aprifel\",\"breadcrumb\":{\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.aprifel.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R\u00e9sum\u00e9s\",\"item\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\",\"url\":\"https:\/\/www.aprifel.com\/fr\/\",\"name\":\"Aprifel\",\"description\":\"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet - Aprifel","description":"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet - Aprifel","robots":{"index":"noindex","follow":"follow"},"og_locale":"fr_FR","og_type":"article","og_title":"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet","og_description":"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet","og_url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/","og_site_name":"Aprifel","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/","url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/","name":"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet - Aprifel","isPartOf":{"@id":"https:\/\/www.aprifel.com\/fr\/#website"},"datePublished":"2018-12-04T06:06:40+00:00","dateModified":"2018-12-04T06:06:40+00:00","description":"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet - Aprifel","breadcrumb":{"@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/hawthorn-fruit-is-hypolipidemic-in-rabbits-fed-a-high-cholesterol\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.aprifel.com\/fr\/"},{"@type":"ListItem","position":2,"name":"R\u00e9sum\u00e9s","item":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/"},{"@type":"ListItem","position":3,"name":"Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet"}]},{"@type":"WebSite","@id":"https:\/\/www.aprifel.com\/fr\/#website","url":"https:\/\/www.aprifel.com\/fr\/","name":"Aprifel","description":"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"}]}},"_links":{"self":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume\/55840"}],"collection":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume"}],"about":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/types\/resume"}],"wp:attachment":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/media?parent=55840"}],"wp:term":[{"taxonomy":"mots_cles","embeddable":true,"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/mots_cles?post=55840"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}