{"id":55730,"date":"2001-06-01T00:00:00","date_gmt":"2018-12-04T06:05:04","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/using-isothiocyanate-excretion-as-a-biological-marker-of-brassica\/"},"modified":"2018-12-04T07:05:04","modified_gmt":"2018-12-04T06:05:04","slug":"using-isothiocyanate-excretion-as-a-biological-marker-of-brassica","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/using-isothiocyanate-excretion-as-a-biological-marker-of-brassica\/","title":{"rendered":"Using isothiocyanate excretion as a biological marker of Brassica vegetable consumption in epidemiological studies: evaluating the sources of variability"},"content":{"rendered":"<p style=\"text-align: justify\"><strong>Objective: <\/strong><br \/>\nBrassica vegetable consumption (e.g. broccoli) leads to excretion of isothiocyanates (ITC) in urine. We evaluated the consistency of ITC as a biomarker for dietary Brassica vegetable consumption across the types of vegetables and methods of preparation used in Western societies, and across consumption levels.<\/p>\n<p style=\"text-align: justify\"><strong>Design: <\/strong><br \/>\nA single-armed behavioural intervention with duplicate baseline assessment and post-intervention assessment. Urinary ITC excretion and estrogen metabolites were measured from 24-hour urine samples. Dietary intake was measured by a 24-hour recall.<\/p>\n<p style=\"text-align: justify\"><strong>Setting: <\/strong><br \/>\nThe behavioural intervention facilitated daily Brassica intake among participants by providing peer support, food preparation instruction, guided practice in a teaching kitchen, and other information.<\/p>\n<p style=\"text-align: justify\"><strong>Subjects:<\/strong><br \/>\nThirty-four healthy free-living postmenopausal women who recently had a negative screening mammogram at the University of Massachusetts Medical Center.<\/p>\n<p style=\"text-align: justify\"><strong>Results:<\/strong><br \/>\nUrinary ITC excretion and total Brassica intake followed the same pattern over the intervention. The ITC biomarker significantly predicted Brassica intake when Brassica consumption averaged about 100 g\/day, but not when Brassica consumption averaged about 200 g\/day. Urinary ITC levels were somewhat higher when more raw vegetables were consumed as compared to lightly cooked vegetables, while the types of Brassica consumed appeared to have only a small, non-significant effect on urinary ITC levels.<\/p>\n<p style=\"text-align: justify\"><strong>Conclusion: <\/strong><br \/>\nUrinary ITC excretion would be a good exposure biomarker among populations regularly consuming a vegetable serving\/day, but may be less accurate among populations with greater intake levels or a wide range of cooking practices.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-55730","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"FOWKE JH,UNIV S CAROLINA,SCH PUBL HLTH DEPT EPIDEMIOL & BIOSTAT; COLUMBIA SC 29208, USA.jay.fowke@palmettohealth.org","annee":"2001","mois":"6","numero":"4:3","page":"837-846","auteurs":[{"ID":55729,"post_author":"0","post_date":"2018-12-04 07:05:03","post_date_gmt":"2018-12-04 06:05:03","post_content":"","post_title":"Katherine K Stephenson","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"katherine-k-stephenson","to_ping":"","pinged":"","post_modified":"2018-12-04 07:05:03","post_modified_gmt":"2018-12-04 06:05:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/katherine-k-stephenson\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":2862,"post_author":"0","post_date":"2018-12-03 16:59:53","post_date_gmt":"2018-12-03 15:59:53","post_content":"","post_title":"Jed W Fahey","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jed-w-fahey","to_ping":"","pinged":"","post_modified":"2018-12-03 16:59:53","post_modified_gmt":"2018-12-03 15:59:53","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jed-w-fahey\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":5434,"post_author":"0","post_date":"2018-12-03 17:27:47","post_date_gmt":"2018-12-03 16:27:47","post_content":"","post_title":"James R Hebert","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"james-r-hebert","to_ping":"","pinged":"","post_modified":"2018-12-03 17:27:47","post_modified_gmt":"2018-12-03 16:27:47","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/james-r-hebert\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":44659,"post_author":"0","post_date":"2018-12-04 03:29:59","post_date_gmt":"2018-12-04 02:29:59","post_content":"","post_title":"Fowke","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"fowke","to_ping":"","pinged":"","post_modified":"2018-12-04 03:29:59","post_modified_gmt":"2018-12-04 02:29:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/fowke\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1299,"post_author":"0","post_date":"2018-12-03 15:58:08","post_date_gmt":"2018-12-03 14:58:08","post_content":"","post_title":"Public health nutrition","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"public-health-nutrition","to_ping":"","pinged":"","post_modified":"2018-12-03 15:58:08","post_modified_gmt":"2018-12-03 14:58:08","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/public-health-nutrition\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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