{"id":54750,"date":"2002-11-01T00:00:00","date_gmt":"2018-12-04T05:49:22","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/circulating-lipid-peroxidation-and-antioxidant-status-in\/"},"modified":"2018-12-04T06:49:22","modified_gmt":"2018-12-04T05:49:22","slug":"circulating-lipid-peroxidation-and-antioxidant-status-in","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/circulating-lipid-peroxidation-and-antioxidant-status-in\/","title":{"rendered":"Circulating lipid peroxidation and antioxidant status in cervical cancer patients: a case-control study"},"content":{"rendered":"

Objectives: The present case-control study was conducted to investigate the status of circulating lipid peroxidation and the enzymic and nonenzymic antioxidants of cervical cancer patients.Design and methods: Plasma thiobarbituric acid reactive substances (TBARS), conjugated dienes (CD) and the levels of antioxidants such as reduced glutathione (GSH), glutathione peroxidase (GPx), glutathione-S-transferase (GST), superoxide dismutase (SOD),vitamin C and vitamin E were estimated in circulation of thirty patients and an equal number of age matched normal subjects as control..Results: Significantly elevated levels of plasma TBARS and CD and significantly lowered levels of GSH, GPx, GST, SOD vitamin C and vitamin E were observed in cervical cancer patients as compared to controls. Our study reveals increased lipid peroxidation and possible breakdown of antioxidant status in patients with cervical carcinoma.Conclusion: These results indicate that low levels of GSH, GPx, GST, SOD, vitamin E and vitamin C in the circulation of cervical cancer patients may be due to their increased utilization to scavenge lipid peroxides as well as their sequestration by tumor cells. Malnutrition may also be a significant cause for the increased prevalence of cervical cancer in women with a low socioeconomic status.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-54750","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"\"NALINI N,ANNAMALAI UNIV,DEPT BIOCHEM; ANNAMALAINAGAR TAMIL NADU 608002, INDIA. nalininam@yahoo.com \"","annee":"2002","mois":"11","numero":"35:8","page":"621-625","auteurs":[{"ID":54747,"post_author":"0","post_date":"2018-12-04 06:49:20","post_date_gmt":"2018-12-04 05:49:20","post_content":"","post_title":"Manju","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"manju","to_ping":"","pinged":"","post_modified":"2018-12-04 06:49:20","post_modified_gmt":"2018-12-04 05:49:20","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/manju\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54748,"post_author":"0","post_date":"2018-12-04 06:49:21","post_date_gmt":"2018-12-04 05:49:21","post_content":"","post_title":"Nalini","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"nalini","to_ping":"","pinged":"","post_modified":"2018-12-04 06:49:21","post_modified_gmt":"2018-12-04 05:49:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/nalini\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54749,"post_author":"0","post_date":"2018-12-04 06:49:21","post_date_gmt":"2018-12-04 05:49:21","post_content":"","post_title":"Sailaja","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sailaja","to_ping":"","pinged":"","post_modified":"2018-12-04 06:49:21","post_modified_gmt":"2018-12-04 05:49:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sailaja\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":3282,"post_author":"0","post_date":"2018-12-03 17:04:02","post_date_gmt":"2018-12-03 16:04:02","post_content":"","post_title":"CLINICAL BIOCHEMISTRY","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"clinical-biochemistry","to_ping":"","pinged":"","post_modified":"2018-12-03 17:04:02","post_modified_gmt":"2018-12-03 16:04:02","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/clinical-biochemistry\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nCirculating lipid peroxidation and antioxidant status in cervical cancer patients: a case-control study - 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