{"id":54457,"date":"2003-02-01T00:00:00","date_gmt":"2018-12-04T05:44:11","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/persistent-chlorinated-pesticides-and-intra-uterine-foetal\/"},"modified":"2018-12-04T06:44:11","modified_gmt":"2018-12-04T05:44:11","slug":"persistent-chlorinated-pesticides-and-intra-uterine-foetal","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/persistent-chlorinated-pesticides-and-intra-uterine-foetal\/","title":{"rendered":"Persistent chlorinated pesticides and intra-uterine foetal growth retardation: a possible association"},"content":{"rendered":"<p>\u00ab\u00a0Objective: To examine the association between DDT (dichlorodiphenyl trichloroethane) and HCH (hexachlorocyclohexane) exposure and intrauterine growth retardation (IUGR, &lt; 10th percentile of birth weight for gestational age). Method: We detected p,p&#039;-DDT, o,p&#039;-DDT, p,p&#039;-DDD, p,p&#039;-DDE and alpha-HCH, beta-HCH, gamma-HCH, delta-HCH in maternal blood, placenta and cord blood, collected at parturition, from mothers with IUGR babies (n = 30) and from those with babies of normal weight (n = 24), using gas-liquid chromatography equipped with electron capture detector (Ni-63). The adjusted odds ratios (ORs) for these pesticides in mothers and infants were determined by multiple logistic regression. Results: There were statistically significant associations (P &lt; 0.05) between maternal blood levels of alpha-HCH (OR = 1.22; 95% CI: 1.02-1.46), gamma-HCH (OR = 1.38; 95%CI: 1.05-1.80), delta-HCH (OR = 1.61; 95% CI: 1.01-2.54), total HCH (OR = 1.07; 95% CI: 1.01-1.13) and p,p&#039;-DDE (OR = 1.21; 95% CI:1.03-1.42) and IUGR after adjustment for potential confounders. Also, significant association (P &lt; 0.05) between cord blood levels of gamma-HCH (OR = 1.14; 95% CI: 1.00-1.31), delta-HCH (OR = 1.31; 95% CI: 1.00-1.75), total HCH (OR = 1.07; 95% CI: 1.00-1.14) and IUGR were found after adjustment for potential confounders. A significant negative correlation between body weight of newborn babies and p,p&#039;-DDE in maternal blood (r = -0.25; P &lt; 0.05) and delta-HCH and p,p&#039;-DDE in the cord blood (r = -0.27 and -0.26; P &lt; 0.05) was noticed after gestational age had been accounted for. Conclusion: Exposure of pregnant women to organochlorine pesticides may increase the risk of IUGR, which is a contributing factor for infant mortality in India.&quot;<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-54457","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"\"SIDDIQUI MKJ,IND TOXICOL RES CTR;POST BOX 80,MG MARG; LUCKNOW UTTAR PRADESH 226001, INDIA.mkjs@rediffmail.com \"","annee":"2003","mois":"2","numero":"76:1","page":"75-80","auteurs":[{"ID":54452,"post_author":"0","post_date":"2018-12-04 06:44:03","post_date_gmt":"2018-12-04 05:44:03","post_content":"","post_title":"Mathur","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"mathur","to_ping":"","pinged":"","post_modified":"2018-12-04 06:44:03","post_modified_gmt":"2018-12-04 05:44:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/mathur\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54453,"post_author":"0","post_date":"2018-12-04 06:44:05","post_date_gmt":"2018-12-04 05:44:05","post_content":"","post_title":"Mehrotra","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"mehrotra","to_ping":"","pinged":"","post_modified":"2018-12-04 06:44:05","post_modified_gmt":"2018-12-04 05:44:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/mehrotra\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54454,"post_author":"0","post_date":"2018-12-04 06:44:06","post_date_gmt":"2018-12-04 05:44:06","post_content":"","post_title":"Siddiqui","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"siddiqui-2","to_ping":"","pinged":"","post_modified":"2018-12-04 06:44:06","post_modified_gmt":"2018-12-04 05:44:06","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/siddiqui-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":30720,"post_author":"0","post_date":"2018-12-03 23:35:32","post_date_gmt":"2018-12-03 22:35:32","post_content":"","post_title":"Sanjay K Srivastava","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sanjay-k-srivastava","to_ping":"","pinged":"","post_modified":"2018-12-03 23:35:32","post_modified_gmt":"2018-12-03 22:35:32","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sanjay-k-srivastava\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54455,"post_author":"0","post_date":"2018-12-04 06:44:09","post_date_gmt":"2018-12-04 05:44:09","post_content":"","post_title":"Srivastava","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"srivastava-4","to_ping":"","pinged":"","post_modified":"2018-12-04 06:44:09","post_modified_gmt":"2018-12-04 05:44:09","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/srivastava-4\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54456,"post_author":"0","post_date":"2018-12-04 06:44:10","post_date_gmt":"2018-12-04 05:44:10","post_content":"","post_title":"Tandon","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"tandon","to_ping":"","pinged":"","post_modified":"2018-12-04 06:44:10","post_modified_gmt":"2018-12-04 05:44:10","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/tandon\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":16722,"post_author":"0","post_date":"2018-12-03 19:42:31","post_date_gmt":"2018-12-03 18:42:31","post_content":"","post_title":"INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"international-archives-of-occupational-and-environmental-health","to_ping":"","pinged":"","post_modified":"2018-12-03 19:42:31","post_modified_gmt":"2018-12-03 18:42:31","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/international-archives-of-occupational-and-environmental-health\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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