{"id":54226,"date":"2003-06-01T00:00:00","date_gmt":"2018-12-04T05:35:54","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/energy-macronutrients-and-laryngeal-cancer-risk\/"},"modified":"2018-12-04T06:35:54","modified_gmt":"2018-12-04T05:35:54","slug":"energy-macronutrients-and-laryngeal-cancer-risk","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/energy-macronutrients-and-laryngeal-cancer-risk\/","title":{"rendered":"Energy, macronutrients and laryngeal cancer risk."},"content":{"rendered":"<p>BACKGROUND: A role for diet in laryngeal carcinogenesis has been suggested, but only a few studies have examined the potential relationship with a wide variety of macronutrients. PATIENTS AND METHODS: A case-control study was conducted between 1992 and 2000 in Italy and Switzerland, including 527 incident cases of laryngeal cancer, and 1297 controls hospitalized for acute, non-neoplastic conditions. The subjects&rsquo; usual diet was investigated through a validated food frequency questionnaire, including 78 foods and beverages. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using unconditional multiple logistic regression models. RESULTS: Cases reported higher energy intake than controls. The continuous OR for 100 kcal\/day was 1.16 (95% CI 1.12-1.21) for alcohol energy, and 1.02 (95% CI 1.01-1.04) for non-alcohol energy. A significantly increased risk of laryngeal cancer was observed for animal protein (continuous OR = 1.21, 95% CI 1.03-1.41), polyunsaturated fats other than linoleic and linolenic fatty acids (OR = 1.43, 95% CI 1.19-1.70), and cholesterol intake (OR = 1.43, 95% CI 1.19-1.71). Laryngeal cancer risk was slightly reduced with increasing vegetable protein (OR = 0.75, 95% CI 0.62-0.91), sugar (OR = 0.84, 95% CI 0.71-1.00) and monounsaturated fatty acid intake (OR = 0.83, 95% CI 0.70-0.99). CONCLUSIONS: Laryngeal cancer cases have a higher energy intake than control subjects, and report a higher intake of animal protein and cholesterol.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-54226","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Istituto di Ricerche Farmacologiche Mario Negri, Milan.","annee":"2003","mois":"6","numero":"14:6","page":"907-912","auteurs":[{"ID":17638,"post_author":"0","post_date":"2018-12-03 19:54:47","post_date_gmt":"2018-12-03 18:54:47","post_content":"","post_title":"Cristina Bosetti","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"cristina-bosetti","to_ping":"","pinged":"","post_modified":"2018-12-03 19:54:47","post_modified_gmt":"2018-12-03 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