{"id":54182,"date":"2003-03-01T00:00:00","date_gmt":"2018-12-04T05:34:33","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/"},"modified":"2018-12-04T06:34:33","modified_gmt":"2018-12-04T05:34:33","slug":"plant-foods-versus-compounds-in-carcinogenesis-observational","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/","title":{"rendered":"\u00ab\u00a0Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \u00ab\u00a0"},"content":{"rendered":"

The protective role of plant foods and its constituents in cancer prevention is under renewed debate since the results of recent observational studies on colorectal cancer as well as large-scale human experimental studies on colorectal adenoma recurrence are disappointing. However, most short-term experimental human studies do show that plant foods favourably modulate potential cancer-preventive mechanisms. Which methodological pitfalls may explain the inconsistencies within and between different study designs? What are the advantages and limitations of the different study approaches? Observational Studies do have the advantage to study the population at large with ultimate disease as the study endpoint. These studies are limited by the difficulty to estimate intake of individual compounds by questionnaires and the lack of biological markers of relevant exposure. Controlled experimental short-term studies in humans rely on biological markers of disease as intermediate endpoints. Relatively low sensitivity and specificity of these markers may complicate extrapolation of results. In the case of long-term and large-scale human intervention studies with disease endpoints, issues such as time, dose and duration of intervention, compliance and choice of the study population influence the interpretation of results.An integrated approach combining designs, and implementing new techniques to identify biomarkers, may clarify the role of plant foods in carcinogenesis.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-54182","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"KAMPMAN E,UNIV WAGENINGEN & RES CTR,DIV HUMAN NUTR & EPIDEMIOL;POB 8129;NL-6700 EV WAGENINGEN, NETHERLANDS.ellen.kampman@wur.nl","annee":"2003","mois":"3","numero":"73:2","page":"70-78","auteurs":[{"ID":50446,"post_author":"0","post_date":"2018-12-04 05:16:47","post_date_gmt":"2018-12-04 04:16:47","post_content":"","post_title":"Hollman","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hollman","to_ping":"","pinged":"","post_modified":"2018-12-04 05:16:47","post_modified_gmt":"2018-12-04 04:16:47","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hollman\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":43439,"post_author":"0","post_date":"2018-12-04 03:07:03","post_date_gmt":"2018-12-04 02:07:03","post_content":"","post_title":"Arts","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"arts","to_ping":"","pinged":"","post_modified":"2018-12-04 03:07:03","post_modified_gmt":"2018-12-04 02:07:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/arts\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":13170,"post_author":"0","post_date":"2018-12-03 18:55:03","post_date_gmt":"2018-12-03 17:55:03","post_content":"","post_title":"Ellen Kampman","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ellen-kampman","to_ping":"","pinged":"","post_modified":"2018-12-03 18:55:03","post_modified_gmt":"2018-12-03 17:55:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ellen-kampman\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":44239,"post_author":"0","post_date":"2018-12-04 03:20:00","post_date_gmt":"2018-12-04 02:20:00","post_content":"","post_title":"INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"international-journal-for-vitamin-and-nutrition-research","to_ping":"","pinged":"","post_modified":"2018-12-04 03:20:00","post_modified_gmt":"2018-12-04 02:20:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/international-journal-for-vitamin-and-nutrition-research\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\n"Plant foods versus compounds in carcinogenesis; observational versus experimental human studies " - Aprifel<\/title>\n<meta name=\"description\" content=\""Plant foods versus compounds in carcinogenesis; observational versus experimental human studies " - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\""Plant foods versus compounds in carcinogenesis; observational versus experimental human studies "\" \/>\n<meta property=\"og:description\" content=\""Plant foods versus compounds in carcinogenesis; observational versus experimental human studies "\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/\",\"name\":\"\\\"Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \\\" - Aprifel\",\"isPartOf\":{\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\"},\"datePublished\":\"2018-12-04T05:34:33+00:00\",\"dateModified\":\"2018-12-04T05:34:33+00:00\",\"description\":\"\\\"Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \\\" - Aprifel\",\"breadcrumb\":{\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.aprifel.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R\u00e9sum\u00e9s\",\"item\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"\u00ab\u00a0Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \u00ab\u00a0\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\",\"url\":\"https:\/\/www.aprifel.com\/fr\/\",\"name\":\"Aprifel\",\"description\":\"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"\"Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \" - Aprifel","description":"\"Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \" - Aprifel","robots":{"index":"noindex","follow":"follow"},"og_locale":"fr_FR","og_type":"article","og_title":"\"Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \"","og_description":"\"Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \"","og_url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/","og_site_name":"Aprifel","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/","url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/","name":"\"Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \" - Aprifel","isPartOf":{"@id":"https:\/\/www.aprifel.com\/fr\/#website"},"datePublished":"2018-12-04T05:34:33+00:00","dateModified":"2018-12-04T05:34:33+00:00","description":"\"Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \" - Aprifel","breadcrumb":{"@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plant-foods-versus-compounds-in-carcinogenesis-observational\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.aprifel.com\/fr\/"},{"@type":"ListItem","position":2,"name":"R\u00e9sum\u00e9s","item":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/"},{"@type":"ListItem","position":3,"name":"\u00ab\u00a0Plant foods versus compounds in carcinogenesis; observational versus experimental human studies \u00ab\u00a0"}]},{"@type":"WebSite","@id":"https:\/\/www.aprifel.com\/fr\/#website","url":"https:\/\/www.aprifel.com\/fr\/","name":"Aprifel","description":"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"}]}},"_links":{"self":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume\/54182"}],"collection":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume"}],"about":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/types\/resume"}],"wp:attachment":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/media?parent=54182"}],"wp:term":[{"taxonomy":"mots_cles","embeddable":true,"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/mots_cles?post=54182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}