{"id":54181,"date":"2003-05-01T00:00:00","date_gmt":"2018-12-04T05:34:29","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effect-of-supplemental-phytonutrients-on-impairment-of-the\/"},"modified":"2018-12-04T06:34:29","modified_gmt":"2018-12-04T05:34:29","slug":"effect-of-supplemental-phytonutrients-on-impairment-of-the","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effect-of-supplemental-phytonutrients-on-impairment-of-the\/","title":{"rendered":"Effect of supplemental phytonutrients on impairment of the flow-mediated brachial artery vasoactivity after a single high-fat meal"},"content":{"rendered":"<p>\u00ab\u00a0OBJECTIVES Our objective was to determine if long-term daily administration of phytonutrient supplements can prevent the immediate adverse impact of a high-fat meal and increase the production of nitric oxide.BACKGROUND Ingestion of a high-fat meal impairs flow-mediated vasodilation of the brachial artery for at least 4 h; however, co-ingestion of vitamin antioxidants or a green salad has been shown to prevent this effect.METHODS Flow-mediated brachial artery reactivity test (BART) both before and 3 h after a 900 calorie 50 g fat meal was evaluated in 38 healthy volunteers (age 36.4 +\/- 10.1 years). Subjects were randomized to four weeks of daily supplementation with a powdered fruit vegetable juice concentrate (Juice Plus [JP]) along with a complex supplement providing nutritional antioxidants and various herbal extracts (Vineyard [V]), JP alone, or a matching placebo. At three and four weeks, BART was repeated both before and after the high-fat meal. Serum nitrate\/nitrite concentrations were measured at baseline and at four weeks.RESULTS Four weeks of the JP-V combination blunted the detrimental effect of the high-fat meal (-47.5 +\/- 23.4% at baseline vs. -1.7 +\/- 9.7% at four weeks [p &lt; 0.05]). Four weeks of JP alone had a similar beneficial effect (-45.1 +\/- 19.7% at baseline vs. -16.6 +\/- 10.3% at four weeks [p &lt; 0.05]), whereas there was no substantial effect of the placebo. In the subjects treated with supplements, concentrations of serum nitrate\/nitrite increased from 78 +\/- 39 to 114 +\/- 62 mum\/1 (p &lt; 0.02).CONCLUSIONS Daily ingestion of modest amounts of a fruit\/vegetable juice concentrate with or without adjunctive phytonutrient supplementation can reduce the immediate adverse impact of high-fat meals on flow-mediated vasoactivity and increase nitrate\/nitrite blood concentration. (C) 2003 by the American College of Cardiology Foundation. &quot;<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-54181","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"\"PLOTNICK GD,UNIV MARYLAND,MED CTR DIV CARDIOL SCH MED;22 S GREENE ST; BALTIMORE MD 21201, USA.gplotnic@medicine.umaryland.edu  \"","annee":"2003","mois":"5","numero":"41:10","page":"1744-1749","auteurs":[{"ID":54177,"post_author":"0","post_date":"2018-12-04 06:34:24","post_date_gmt":"2018-12-04 05:34:24","post_content":"","post_title":"Corretti","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"corretti","to_ping":"","pinged":"","post_modified":"2018-12-04 06:34:24","post_modified_gmt":"2018-12-04 05:34:24","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/corretti\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54178,"post_author":"0","post_date":"2018-12-04 06:34:25","post_date_gmt":"2018-12-04 05:34:25","post_content":"","post_title":"Plotnick","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"plotnick","to_ping":"","pinged":"","post_modified":"2018-12-04 06:34:25","post_modified_gmt":"2018-12-04 05:34:25","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/plotnick\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54179,"post_author":"0","post_date":"2018-12-04 06:34:26","post_date_gmt":"2018-12-04 05:34:26","post_content":"","post_title":"Vogel","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"vogel-4","to_ping":"","pinged":"","post_modified":"2018-12-04 06:34:26","post_modified_gmt":"2018-12-04 05:34:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/vogel-4\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54180,"post_author":"0","post_date":"2018-12-04 06:34:28","post_date_gmt":"2018-12-04 05:34:28","post_content":"","post_title":"Hesslink","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hesslink","to_ping":"","pinged":"","post_modified":"2018-12-04 06:34:28","post_modified_gmt":"2018-12-04 05:34:28","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hesslink\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":40597,"post_author":"0","post_date":"2018-12-04 02:16:59","post_date_gmt":"2018-12-04 01:16:59","post_content":"","post_title":"Wise","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"wise-2","to_ping":"","pinged":"","post_modified":"2018-12-04 02:16:59","post_modified_gmt":"2018-12-04 01:16:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/wise-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":3098,"post_author":"0","post_date":"2018-12-03 17:02:17","post_date_gmt":"2018-12-03 16:02:17","post_content":"","post_title":"JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"journal-of-the-american-college-of-cardiology","to_ping":"","pinged":"","post_modified":"2018-12-03 17:02:17","post_modified_gmt":"2018-12-03 16:02:17","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/journal-of-the-american-college-of-cardiology\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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