{"id":54162,"date":"2003-04-01T00:00:00","date_gmt":"2018-12-04T05:33:59","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/"},"modified":"2018-12-04T06:33:59","modified_gmt":"2018-12-04T05:33:59","slug":"the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/","title":{"rendered":"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent"},"content":{"rendered":"<p>We have investigated the hypoglycemic effect induced by the starch obtained from the unripe fruits of Solanum lycocarpum (Solanaceae). Per os administration of the starch (1000 or 2000 mg\/kg, twice daily for 7 days, N = 6) did not change glycemia levels of nondiabetic female Swiss mice weighing 25-30 g. In streptozotocin-induced diabetic mice, similar treatment with the starch did not change the elevated glycemia 3 h after the last dose (diabetic treated with saline = 288 17\/309 18; starch 1000 mg\/kg = 295 +\/- 33; starch 2000 mg\/kg = 258 +\/- 37; N = 5). In animals fasted for 15 h, per os administration of glucose (600 mg\/kg) significantly increased glycemia 1 h later. Previous (-30 min) treatment of the animals with the starch (1000 or 2000 mg\/kg; N = 5) did not change the increase of glycemia. Per os administration of the starch (1000 or 2000 mg kg-1 day-1, twice daily for 7 days) did not induce body weight gain or loss. The chemical analysis of the starch indicated the presence of glycoalkaloids, a finding that represents a reason for concern since many of these substances are generally toxic. In interviews with 56 diabetic patients, 29 medicinal plants were reported as useful in their treatment of diabetes and S. lycocarpum was the sixth most frequently mentioned. All patients interviewed reported that they also used insulin or oral hypoglycemic drugs. The results of the present study do not provide evidence for a hypoglycemic effect associated with the polysaccharide fraction of S. lycocarpum in either normal or hyperglycemic mice. These data demonstrate the need for adequate pharmacological investigation of the natural products widely used in folk medicine.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-54162","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"\"COELHO MM,UNIV FED MINAS GERAIS,FARMACOL LAB FAC FARM;AV OLEGARIO MACIEL 2360;BR-30180112 BELO HORIZONTE MG, BRAZIL.mmcoelho@farmacia.ufmg.br \"","annee":"2003","mois":"4","numero":"36:4","page":"525-530","auteurs":[{"ID":54157,"post_author":"0","post_date":"2018-12-04 06:33:53","post_date_gmt":"2018-12-04 05:33:53","post_content":"","post_title":"Araujo","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"araujo","to_ping":"","pinged":"","post_modified":"2018-12-04 06:33:53","post_modified_gmt":"2018-12-04 05:33:53","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/araujo\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54158,"post_author":"0","post_date":"2018-12-04 06:33:54","post_date_gmt":"2018-12-04 05:33:54","post_content":"","post_title":"Brandao","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"brandao","to_ping":"","pinged":"","post_modified":"2018-12-04 06:33:54","post_modified_gmt":"2018-12-04 05:33:54","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/brandao\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54159,"post_author":"0","post_date":"2018-12-04 06:33:55","post_date_gmt":"2018-12-04 05:33:55","post_content":"","post_title":"Coelho","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"coelho-2","to_ping":"","pinged":"","post_modified":"2018-12-04 06:33:55","post_modified_gmt":"2018-12-04 05:33:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/coelho-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54160,"post_author":"0","post_date":"2018-12-04 06:33:57","post_date_gmt":"2018-12-04 05:33:57","post_content":"","post_title":"Endringer","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"endringer","to_ping":"","pinged":"","post_modified":"2018-12-04 06:33:57","post_modified_gmt":"2018-12-04 05:33:57","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/endringer\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":54161,"post_author":"0","post_date":"2018-12-04 06:33:58","post_date_gmt":"2018-12-04 05:33:58","post_content":"","post_title":"Oliveira","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"oliveira-5","to_ping":"","pinged":"","post_modified":"2018-12-04 06:33:58","post_modified_gmt":"2018-12-04 05:33:58","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/oliveira-5\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":45691,"post_author":"0","post_date":"2018-12-04 03:45:12","post_date_gmt":"2018-12-04 02:45:12","post_content":"","post_title":"BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"brazilian-journal-of-medical-and-biological-research","to_ping":"","pinged":"","post_modified":"2018-12-04 03:45:12","post_modified_gmt":"2018-12-04 02:45:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/brazilian-journal-of-medical-and-biological-research\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent - Aprifel<\/title>\n<meta name=\"description\" content=\"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent\" \/>\n<meta property=\"og:description\" content=\"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/\",\"name\":\"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent - Aprifel\",\"isPartOf\":{\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\"},\"datePublished\":\"2018-12-04T05:33:59+00:00\",\"dateModified\":\"2018-12-04T05:33:59+00:00\",\"description\":\"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent - Aprifel\",\"breadcrumb\":{\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.aprifel.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R\u00e9sum\u00e9s\",\"item\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\",\"url\":\"https:\/\/www.aprifel.com\/fr\/\",\"name\":\"Aprifel\",\"description\":\"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent - Aprifel","description":"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent - Aprifel","robots":{"index":"noindex","follow":"follow"},"og_locale":"fr_FR","og_type":"article","og_title":"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent","og_description":"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent","og_url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/","og_site_name":"Aprifel","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/","url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/","name":"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent - Aprifel","isPartOf":{"@id":"https:\/\/www.aprifel.com\/fr\/#website"},"datePublished":"2018-12-04T05:33:59+00:00","dateModified":"2018-12-04T05:33:59+00:00","description":"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent - Aprifel","breadcrumb":{"@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-starch-from-solanum-lycocarpum-st-hill-fruit-is-not-a-hypoglycemic\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.aprifel.com\/fr\/"},{"@type":"ListItem","position":2,"name":"R\u00e9sum\u00e9s","item":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/"},{"@type":"ListItem","position":3,"name":"The starch from solanum lycocarpum st. hill. fruit is not a hypoglycemic agent"}]},{"@type":"WebSite","@id":"https:\/\/www.aprifel.com\/fr\/#website","url":"https:\/\/www.aprifel.com\/fr\/","name":"Aprifel","description":"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"}]}},"_links":{"self":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume\/54162"}],"collection":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume"}],"about":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/types\/resume"}],"wp:attachment":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/media?parent=54162"}],"wp:term":[{"taxonomy":"mots_cles","embeddable":true,"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/mots_cles?post=54162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}