{"id":53021,"date":"2003-09-01T00:00:00","date_gmt":"2018-12-04T05:12:42","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-fat-soluble-extracts-from-vegetable-powder-and\/"},"modified":"2018-12-04T06:12:42","modified_gmt":"2018-12-04T05:12:42","slug":"effects-of-fat-soluble-extracts-from-vegetable-powder-and","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-fat-soluble-extracts-from-vegetable-powder-and\/","title":{"rendered":"Effects of fat-soluble extracts from vegetable powder and beta-carotene on proliferation and apoptosis of lung cancer cell ytmlc-90."},"content":{"rendered":"<p>OBJECTIVE: The aim of this investigation was to study the effects of fat-soluble extracts from vegetable powder (FEFVP) and beta-carotene on the proliferation and apoptosis of cultured YTMLC-90 lung cancer cells. METHODS: The lung cancer cells were continuously exposed to a broad range of concentration of FEFVP and beta-carotene. The proliferation was evaluated in MTT test. The induction of apoptosis was evaluated by morphological change, DNA fragmentation analysis, and DNA content analysis combined with flow cytometric analysis. RESULTS: Both FEFVP and beta-carotene were found to inhibit cell proliferation and to induce morphologic changes consistent with apoptosis in YTMLC-90 cancer cells, including cellular shrinkage, chromatin condensation and nuclear fragmentation. DNA agarose gel electrophoresis showed DNA fragmentation &lsquo;ladder&rsquo;. Flow cytometric analysis revealed decreased DNA content and the presence of a sub-G1 apoptotic peak. CONCLUSION: These findings are consistent with the induction of apoptosis. Moreover, the effects of FEFVP are stronger than those of beta-carotene. FEFVP inhibits the growth of YTMLC-90 probably via the induction of apoptosis cancer cells.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-53021","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou 450052, Henan, China. lqjnutr@zzu.edu.cn","annee":"2003","mois":"9","numero":"16:3","page":"237-245","auteurs":[{"ID":19551,"post_author":"0","post_date":"2018-12-03 20:22:53","post_date_gmt":"2018-12-03 19:22:53","post_content":"","post_title":"Christina Y Huang","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"christina-y-huang","to_ping":"","pinged":"","post_modified":"2018-12-03 20:22:53","post_modified_gmt":"2018-12-03 19:22:53","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/christina-y-huang\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":53017,"post_author":"0","post_date":"2018-12-04 06:12:39","post_date_gmt":"2018-12-04 05:12:39","post_content":"","post_title":"Lu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lu-3","to_ping":"","pinged":"","post_modified":"2018-12-04 06:12:39","post_modified_gmt":"2018-12-04 05:12:39","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/lu-3\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":53018,"post_author":"0","post_date":"2018-12-04 06:12:40","post_date_gmt":"2018-12-04 05:12:40","post_content":"","post_title":"Wang","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"wang-11","to_ping":"","pinged":"","post_modified":"2018-12-04 06:12:40","post_modified_gmt":"2018-12-04 05:12:40","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/wang-11\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":53019,"post_author":"0","post_date":"2018-12-04 06:12:41","post_date_gmt":"2018-12-04 05:12:41","post_content":"","post_title":"Wu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"wu-15","to_ping":"","pinged":"","post_modified":"2018-12-04 06:12:41","post_modified_gmt":"2018-12-04 05:12:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/wu-15\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":53020,"post_author":"0","post_date":"2018-12-04 06:12:42","post_date_gmt":"2018-12-04 05:12:42","post_content":"","post_title":"Yao","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"yao-2","to_ping":"","pinged":"","post_modified":"2018-12-04 06:12:42","post_modified_gmt":"2018-12-04 05:12:42","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/yao-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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