{"id":52984,"date":"2003-12-01T00:00:00","date_gmt":"2018-12-04T05:12:07","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/tomatoes-have-natural-anti-thrombotic-effects\/"},"modified":"2018-12-04T06:12:07","modified_gmt":"2018-12-04T05:12:07","slug":"tomatoes-have-natural-anti-thrombotic-effects","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/tomatoes-have-natural-anti-thrombotic-effects\/","title":{"rendered":"Tomatoes have natural anti-thrombotic effects."},"content":{"rendered":"<p>The prevention of arterial thrombotic diseases has a high priority in developed countries. An inappropriate diet may be an important risk factor for thrombotic events. The daily intake of an anti-thrombotic diet may offer a convenient and effective way of prevention. The aim of the present study was to test tomato extracts for anti-thrombotic effects and to identify those varieties that have such an effect. A shear-induced platelet-function test (haemostatometry) was used to test anti-thrombotic potential in vitro. Extracts from those tomato varieties that showed a significant anti-thrombotic activity in vitro were further assessed in vivo, using a laser-induced thrombosis test in mice. One tomato variety (KG99-4) showed significant anti-thrombotic activity both in vitro and in vivo. KG99-4 inhibited not only platelet-rich thrombus formation but also had a thrombolytic effect. It is concluded that haemostatometry can detect and classify the anti-thrombotic potential of fruits and vegetables and offers a simple way of screening for such effects.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-52984","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Laboratory of Physiology, Faculty of Nutrition and High Technology Research Centre, Kobe Gakuin University, Kobe, Japan. yamamoto@nutr.kobegakuin.ac.jp","annee":"2003","mois":"12","numero":"90:6","page":"1031-1038","auteurs":[{"ID":51783,"post_author":"0","post_date":"2018-12-04 05:44:12","post_date_gmt":"2018-12-04 04:44:12","post_content":"","post_title":"Yamada","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"yamada-3","to_ping":"","pinged":"","post_modified":"2018-12-04 05:44:12","post_modified_gmt":"2018-12-04 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