{"id":50810,"date":"2004-06-01T00:00:00","date_gmt":"2018-12-04T04:24:47","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/"},"modified":"2018-12-04T05:24:47","modified_gmt":"2018-12-04T04:24:47","slug":"absence-of-an-effect-of-liposuction-on-insulin-action-and-risk","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/","title":{"rendered":"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease."},"content":{"rendered":"<p style=\"text-align: justify\"><strong>BACKGROUND:<\/strong><br \/>\nLiposuction has been proposed as a potential treatment for the metabolic complications of obesity. We evaluated the effect of large-volume abdominal liposuction on metabolic risk factors for coronary heart disease in women with abdominal obesity.<\/p>\n<p style=\"text-align: justify\"><strong>METHODS:<\/strong><br \/>\nWe evaluated the insulin sensitivity of liver, skeletal muscle, and adipose tissue (with a euglycemic-hyperinsulinemic clamp procedure and isotope-tracer infusions) as well as levels of inflammatory mediators and other risk factors for coronary heart disease in 15 obese women before and 10 to 12 weeks after abdominal liposuction. Eight of the women had normal glucose tolerance (mean [+\/-SD] body-mass index, 35.1+\/-2.4), and seven had type 2 diabetes (body-mass index, 39.9+\/-5.6).<\/p>\n<p style=\"text-align: justify\"><strong>RESULTS: <\/strong><br \/>\nLiposuction decreased the volume of subcutaneous abdominal adipose tissue by 44 percent in the subjects with normal glucose tolerance and 28 percent in those with diabetes; those with normal oral glucose tolerance lost 9.1+\/-3.7 kg of fat (18+\/-3 percent decrease in total fat, P=0.002), and those with type 2 diabetes lost 10.5+\/-3.3 kg of fat (19+\/-2 percent decrease in total fat, P&lt;0.001). Liposuction did not significantly alter the insulin sensitivity of muscle, liver, or adipose tissue (assessed by the stimulation of glucose disposal, the suppression of glucose production, and the suppression of lipolysis, respectively); did not significantly alter plasma concentrations of C-reactive protein, interleukin-6, tumor necrosis factor alpha, and adiponectin; and did not significantly affect other risk factors for coronary heart disease (blood pressure and plasma glucose, insulin, and lipid concentrations) in either group.<\/p>\n<p style=\"text-align: justify\"><strong>CONCLUSIONS:<\/strong><br \/>\nAbdominal liposuction does not significantly improve obesity-associated metabolic abnormalities. Decreasing adipose tissue mass alone will not achieve the metabolic benefits of weight loss.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-50810","resume","type-resume","status-publish","hentry"],"acf":{"auteurs":null,"adresse":null,"numero":null,"page":null,"mois":null,"annee":null,"mots-cles":null,"sources":null},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. - Aprifel<\/title>\n<meta name=\"description\" content=\"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease.\" \/>\n<meta property=\"og:description\" content=\"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/\",\"name\":\"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. - Aprifel\",\"isPartOf\":{\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\"},\"datePublished\":\"2018-12-04T04:24:47+00:00\",\"dateModified\":\"2018-12-04T04:24:47+00:00\",\"description\":\"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. - Aprifel\",\"breadcrumb\":{\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.aprifel.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R\u00e9sum\u00e9s\",\"item\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\",\"url\":\"https:\/\/www.aprifel.com\/fr\/\",\"name\":\"Aprifel\",\"description\":\"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. - Aprifel","description":"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. - Aprifel","robots":{"index":"noindex","follow":"follow"},"og_locale":"fr_FR","og_type":"article","og_title":"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease.","og_description":"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease.","og_url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/","og_site_name":"Aprifel","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/","url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/","name":"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. - Aprifel","isPartOf":{"@id":"https:\/\/www.aprifel.com\/fr\/#website"},"datePublished":"2018-12-04T04:24:47+00:00","dateModified":"2018-12-04T04:24:47+00:00","description":"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. - Aprifel","breadcrumb":{"@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/absence-of-an-effect-of-liposuction-on-insulin-action-and-risk\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.aprifel.com\/fr\/"},{"@type":"ListItem","position":2,"name":"R\u00e9sum\u00e9s","item":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/"},{"@type":"ListItem","position":3,"name":"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease."}]},{"@type":"WebSite","@id":"https:\/\/www.aprifel.com\/fr\/#website","url":"https:\/\/www.aprifel.com\/fr\/","name":"Aprifel","description":"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"}]}},"_links":{"self":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume\/50810"}],"collection":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume"}],"about":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/types\/resume"}],"wp:attachment":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/media?parent=50810"}],"wp:term":[{"taxonomy":"mots_cles","embeddable":true,"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/mots_cles?post=50810"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}