{"id":50711,"date":"2005-01-01T00:00:00","date_gmt":"2018-12-04T04:21:44","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-frying-oil-and-houttuynia-cordata-thunb-on-xenobiotic-metabolizing\/"},"modified":"2018-12-04T05:21:44","modified_gmt":"2018-12-04T04:21:44","slug":"effects-of-frying-oil-and-houttuynia-cordata-thunb-on-xenobiotic-metabolizing","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/effects-of-frying-oil-and-houttuynia-cordata-thunb-on-xenobiotic-metabolizing\/","title":{"rendered":"Effects of frying oil and houttuynia cordata thunb on xenobiotic-metabolizing enzyme system of rodents."},"content":{"rendered":"<p>AIM: To evaluate the effects of frying oil and Houttuynia cordata Thunb (H. cordata), a vegetable traditionally consumed in Taiwan, on the xenobiotic-metabolizing enzyme system of rodents. METHODS: Forty-eight Sprague-Dawley rats were fed with a diet containing 0%, 2% or 5% H. cordata powder and 15% fresh soybean oil or 24-h oxidized frying oil (OFO) for 28 d respectively. The level of microsomal protein, total cytochrome 450 content (CYP450) and enzyme activities including NADPH reductase, ethoxyresorufin O-deethylase (EROD), pentoxyresorufin O-dealkylase (PROD), aniline hydroxylase (ANH), aminopyrine demethylase (AMD), and quinone reductase (QR) were determined. QR represented phase II enzymes, the rest of the enzymes tested represented phase I enzymes. RESULTS: The oxidized frying oil feeding produced a significant increase in phase I and II enzyme systems, including the content of CYP450 and microsomal protein, and the activities of NADPH reductase, EROD, PROD, ANH, AMD and QR in rats (P&lt;0.05). In addition, the activities of EROD, ANH and AMD decreased and QR increased after feeding with H. cordata in OFO-fed group (P&lt;0.05). The feeding with 2% H. cordata diet showed the most significant effect. CONCLUSION: The OFO diet induces phases I and II enzyme activity, and the 2% H. cordata diet resulted in a better regulation of the xenobiotic-metabolizing enzyme system.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-50711","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Graduate Institute of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan, China.","annee":"2005","mois":"1","numero":"11:3","page":"389-392","auteurs":[{"ID":37820,"post_author":"0","post_date":"2018-12-04 01:24:17","post_date_gmt":"2018-12-04 00:24:17","post_content":"","post_title":"Chen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"chen-5","to_ping":"","pinged":"","post_modified":"2018-12-04 01:24:17","post_modified_gmt":"2018-12-04 00:24:17","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/chen-5\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50709,"post_author":"0","post_date":"2018-12-04 05:21:40","post_date_gmt":"2018-12-04 04:21:40","post_content":"","post_title":"Chen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"chen-17","to_ping":"","pinged":"","post_modified":"2018-12-04 05:21:40","post_modified_gmt":"2018-12-04 04:21:40","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/chen-17\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":33153,"post_author":"0","post_date":"2018-12-04 00:09:21","post_date_gmt":"2018-12-03 23:09:21","post_content":"","post_title":"Pi-Yu Chao","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"pi-yu-chao","to_ping":"","pinged":"","post_modified":"2018-12-04 00:09:21","post_modified_gmt":"2018-12-03 23:09:21","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/pi-yu-chao\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50710,"post_author":"0","post_date":"2018-12-04 05:21:42","post_date_gmt":"2018-12-04 04:21:42","post_content":"","post_title":"Chang","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"chang-9","to_ping":"","pinged":"","post_modified":"2018-12-04 05:21:42","post_modified_gmt":"2018-12-04 04:21:42","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/chang-9\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":42104,"post_author":"0","post_date":"2018-12-04 02:43:51","post_date_gmt":"2018-12-04 01:43:51","post_content":"","post_title":"Liu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"liu-3","to_ping":"","pinged":"","post_modified":"2018-12-04 02:43:51","post_modified_gmt":"2018-12-04 01:43:51","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/liu-3\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":25398,"post_author":"0","post_date":"2018-12-03 22:19:00","post_date_gmt":"2018-12-03 21:19:00","post_content":"","post_title":"World J Gastroenterol.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"world-j-gastroenterol","to_ping":"","pinged":"","post_modified":"2018-12-03 22:19:00","post_modified_gmt":"2018-12-03 21:19:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/world-j-gastroenterol\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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