{"id":50697,"date":"2005-05-01T00:00:00","date_gmt":"2018-12-04T04:21:18","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-effect-of-a-plant-based-diet-on-plasma-lipids-in-hypercholesterolemic\/"},"modified":"2018-12-04T05:21:18","modified_gmt":"2018-12-04T04:21:18","slug":"the-effect-of-a-plant-based-diet-on-plasma-lipids-in-hypercholesterolemic","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/the-effect-of-a-plant-based-diet-on-plasma-lipids-in-hypercholesterolemic\/","title":{"rendered":"The effect of a plant-based diet on plasma lipids in hypercholesterolemic adults: a randomized trial."},"content":{"rendered":"<p>Comment in:<br \/>\nAnn Intern Med. 2005 May 3;142(9):793-5.<br \/>\nSummary for patients in:<br \/>\nAnn Intern Med. 2005 May 3;142(9):I35.<\/p>\n<p>BACKGROUND: A variety of food combinations can be used to meet national U.S. guidelines for obtaining 30% of energy or less from total fat and 10% of energy or less from saturated fat. OBJECTIVE: To contrast plasma lipid responses to 2 low-fat diet patterns. DESIGN: Randomized clinical trial. SETTING: 4-week outpatient feeding study with weight held constant. PARTICIPANTS: 120 adults 30 to 65 years of age with prestudy low-density lipoprotein (LDL) cholesterol concentrations of 3.3 to 4.8 mmol\/L (130 to 190 mg\/dL), body mass index less than 31 kg\/m2, estimated dietary saturated fat at least 10% of calories, and otherwise general good health. MEASUREMENTS: Plasma lipid levels. INTERVENTION: Two diets, the Low-Fat diet and the Low-Fat Plus diet, designed to be identical in total fat, saturated fat, protein, carbohydrate, and cholesterol content, consistent with former American Heart Association Step I guidelines. The Low-Fat diet was relatively typical of a low-fat U.S. diet. The Low-Fat Plus diet incorporated considerably more vegetables, legumes, and whole grains, consistent with the 2000 American Heart Association revised guidelines. RESULTS: Four-week changes in the Low-Fat and Low-Fat Plus groups were -0.24 mmol\/L (-9.2 mg\/dL) versus -0.46 mmol\/L (-17.6 mg\/dL) for total cholesterol (P = 0.01) and -0.18 mmol\/L (-7.0 mg\/dL) versus -0.36 mmol\/L (-13.8 mg\/dL) for LDL cholesterol (P = 0.02); between-group differences were -0.22 mmol\/L (-9 mg\/dL) (95% CI, -0.05 to -0.39 mmol\/L [-2 to -15 mg\/dL]) and -0.18 mmol\/L (-7 mg\/dL) (CI, -0.04 to -0.32 mmol\/L [-2 to -12 mg\/dL]) for total and LDL cholesterol, respectively. The 2 diet groups did not differ significantly in high-density lipoprotein cholesterol and triglyceride levels. LIMITATIONS: 4-week duration. CONCLUSIONS: Previous national dietary guidelines primarily emphasized avoiding saturated fat and cholesterol; as a result, the guidelines probably underestimated the potential LDL cholesterol-lowering effect of diet. In this study, emphasis on including nutrient-dense plant-based foods, consistent with recently revised national guidelines, increased the total and LDL cholesterol-lowering effect of a low-fat diet.<\/p>\n<p>Publication Types:<br \/>\nClinical Trial<br \/>\nRandomized Controlled Trial <\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-50697","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Stanford University Medical School and Stanford University Medical Center, Stanford, California, USA. cgardner@stanford.edu","annee":"2005","mois":"5","numero":"142:9","page":"725-733","auteurs":[{"ID":11394,"post_author":"0","post_date":"2018-12-03 18:34:46","post_date_gmt":"2018-12-03 17:34:46","post_content":"","post_title":"Christopher D Gardner","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"christopher-d-gardner","to_ping":"","pinged":"","post_modified":"2018-12-03 18:34:46","post_modified_gmt":"2018-12-03 17:34:46","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/christopher-d-gardner\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50692,"post_author":"0","post_date":"2018-12-04 05:21:12","post_date_gmt":"2018-12-04 04:21:12","post_content":"","post_title":"Coulston","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"coulston","to_ping":"","pinged":"","post_modified":"2018-12-04 05:21:12","post_modified_gmt":"2018-12-04 04:21:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/coulston\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50693,"post_author":"0","post_date":"2018-12-04 05:21:14","post_date_gmt":"2018-12-04 04:21:14","post_content":"","post_title":"Chatterjee","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"chatterjee-4","to_ping":"","pinged":"","post_modified":"2018-12-04 05:21:14","post_modified_gmt":"2018-12-04 04:21:14","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/chatterjee-4\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50694,"post_author":"0","post_date":"2018-12-04 05:21:15","post_date_gmt":"2018-12-04 04:21:15","post_content":"","post_title":"Rigby","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"rigby-3","to_ping":"","pinged":"","post_modified":"2018-12-04 05:21:15","post_modified_gmt":"2018-12-04 04:21:15","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/rigby-3\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50695,"post_author":"0","post_date":"2018-12-04 05:21:16","post_date_gmt":"2018-12-04 04:21:16","post_content":"","post_title":"Spiller","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"spiller","to_ping":"","pinged":"","post_modified":"2018-12-04 05:21:16","post_modified_gmt":"2018-12-04 04:21:16","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/spiller\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50696,"post_author":"0","post_date":"2018-12-04 05:21:17","post_date_gmt":"2018-12-04 04:21:17","post_content":"","post_title":"Farquhar","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"farquhar","to_ping":"","pinged":"","post_modified":"2018-12-04 05:21:17","post_modified_gmt":"2018-12-04 04:21:17","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/farquhar\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":16589,"post_author":"0","post_date":"2018-12-03 19:40:52","post_date_gmt":"2018-12-03 18:40:52","post_content":"","post_title":"Annals of internal medicine","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"annals-of-internal-medicine","to_ping":"","pinged":"","post_modified":"2018-12-03 19:40:52","post_modified_gmt":"2018-12-03 18:40:52","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/annals-of-internal-medicine\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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