{"id":50513,"date":"2005-01-01T00:00:00","date_gmt":"2018-12-04T04:17:46","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/increased-risk-of-colorectal-cancer-due-to-interactions-between\/"},"modified":"2018-12-04T05:17:46","modified_gmt":"2018-12-04T04:17:46","slug":"increased-risk-of-colorectal-cancer-due-to-interactions-between","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/increased-risk-of-colorectal-cancer-due-to-interactions-between\/","title":{"rendered":"Increased risk of colorectal cancer due to interactions between meat consumption and the cd36 gene a52c polymorphism among japanese."},"content":{"rendered":"<p>A previous study showed expression of CD36, recently reported to play important roles in metabolism of oxidized low-density lipoprotein and long-chain fatty acids and to be positively correlated with colon cancer prognosis. To examine relationships between colorectal cancer and the CD36 gene A52C polymorphism according to meat consumption as a surrogate for saturated fatty acid intake, we conducted the present hospital-based, case-control study of 128 cases and 238 non-cancer controls. Consumption of meat and vegetables\/fruit was divided into three (low, moderate, and high) and two (low and high) groups, respectively. Regarding the risk of colorectal cancer on cross-classifying subjects for the CD36 genotype and meat consumption, the odds ratio (OR) for the C\/C genotype with moderate meat consumption relative to the A\/A genotype with low meat consumption was 8.30 (95% confidence interval, CI=2.15-32.00). None of individuals with the C\/C genotype was in the high meat consumption group. In the low vegetables\/fruit consumption group, the OR for the C\/C genotype relative to the A\/A genotype was 3.03 (95% CI=1.12-7.90). Our findings suggest that interactions between moderate-high meat consumption and the CD36 gene A52C polymorphism may increase the risk of colorectal cancer.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-50513","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan. kkuriki@aichi-cc.jp","annee":"2005","mois":"0","numero":"51:2","page":"170-177","auteurs":[{"ID":50479,"post_author":"0","post_date":"2018-12-04 05:17:15","post_date_gmt":"2018-12-04 04:17:15","post_content":"","post_title":"Shinkan Tokudome","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"shinkan-tokudome","to_ping":"","pinged":"","post_modified":"2018-12-04 05:17:15","post_modified_gmt":"2018-12-04 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04:17:43","post_content":"","post_title":"Hamajima","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hamajima","to_ping":"","pinged":"","post_modified":"2018-12-04 05:17:43","post_modified_gmt":"2018-12-04 04:17:43","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hamajima\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":48758,"post_author":"0","post_date":"2018-12-04 04:43:07","post_date_gmt":"2018-12-04 03:43:07","post_content":"","post_title":"Tajima","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"tajima","to_ping":"","pinged":"","post_modified":"2018-12-04 04:43:07","post_modified_gmt":"2018-12-04 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03:43:15","post_content":"","post_title":"Hirai","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hirai","to_ping":"","pinged":"","post_modified":"2018-12-04 04:43:15","post_modified_gmt":"2018-12-04 03:43:15","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hirai\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":50511,"post_author":"0","post_date":"2018-12-04 05:17:45","post_date_gmt":"2018-12-04 04:17:45","post_content":"","post_title":"Saito","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"saito-2","to_ping":"","pinged":"","post_modified":"2018-12-04 05:17:45","post_modified_gmt":"2018-12-04 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