Epidemiological studies have suggested that a high consumption of apples may protect against asthma and chronic obstructive pulmonary disease. This effect has been attributed to their high flavonoid content, but few studies have investigated the relationship between flavonoid intake and obstructive lung disease directly. In a population-based, case-control study of 1,471 adults aged 16-50 yrs in London (UK), the present study examined whether dietary intake of catechins, flavonols and flavones was negatively associated with asthma, asthma severity and chronic sputum production. Asthma was defined by positive responses to a standard screening questionnaire in 1996 and information about usual diet was obtained by a food frequency questionnaire in 1997. After controlling for potential confounders, dietary intake of these three flavonoid subclasses was not significantly associated with asthma, (odds ratio per quintile (95% confidence interval)=0.94 (0.86-1.02); 1.00 (0.92-1.09); 0.98 (0.88 -1.08) for flavones, flavonols and total catechins, respectively) nor was it associated with asthma severity, or chronic sputum production. In conclusion, no evidence was found for a protective effect of three major subclasses of dietary flavonoids on asthma. It is possible that other flavonoids or polyphenols present in apples may explain the protective effect of apples on obstructive lung disease.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-49998","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Addresses: Shaheen SO (reprint author), Univ London Kings Coll, Dept Publ Hlth Sci, 5th Floor,Capital House,42 Weston St, London SE1 3QD England\r\nUniv London Kings Coll, Dept Publ Hlth Sci, London SE1 3QD England\r\nUniv Bristol, Dept Social Med, Bristol, Avon England\r\nUniv Southampton, Inst Human Nutr, Southampton, Hants England\r\nUniv Chile, Fac Med, Dept Nutr, Santiago 7 Chile\r\nUniv Wageningen & Res Ctr, Inst Food Safety, RIKILT, Wageningen, Netherlands \r\nE-mail Addresses: seif.shaheen@kcl.ac.uk \r\n\r\nPublisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, 146 WEST ST, STE 2.4, HUTTONS BLDG, SHEFFIELD S1 4ES, ENGLAND \r\nDiscipline: CARDIOVASCULAR & RESPIRATORY SYSTEMS\r\nMEDICAL RESEARCH, ORGANS & SYSTEMS\r\n\r\n\r\n","annee":"2005","mois":"9","numero":"26:3","page":"449-452","auteurs":[{"ID":49995,"post_author":"0","post_date":"2018-12-04 05:08:00","post_date_gmt":"2018-12-04 04:08:00","post_content":"","post_title":"Thompson","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"thompson-9","to_ping":"","pinged":"","post_modified":"2018-12-04 05:08:00","post_modified_gmt":"2018-12-04 04:08:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/thompson-9\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":43439,"post_author":"0","post_date":"2018-12-04 03:07:03","post_date_gmt":"2018-12-04 02:07:03","post_content":"","post_title":"Arts","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"arts","to_ping":"","pinged":"","post_modified":"2018-12-04 03:07:03","post_modified_gmt":"2018-12-04 02:07:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/arts\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":39667,"post_author":"0","post_date":"2018-12-04 02:01:26","post_date_gmt":"2018-12-04 01:01:26","post_content":"","post_title":"Garcia-mediavilla","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"garcia-mediavilla","to_ping":"","pinged":"","post_modified":"2018-12-04 02:01:26","post_modified_gmt":"2018-12-04 01:01:26","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/garcia-mediavilla\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":49996,"post_author":"0","post_date":"2018-12-04 05:08:03","post_date_gmt":"2018-12-04 04:08:03","post_content":"","post_title":"Sterne","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"sterne","to_ping":"","pinged":"","post_modified":"2018-12-04 05:08:03","post_modified_gmt":"2018-12-04 04:08:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/sterne\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":42069,"post_author":"0","post_date":"2018-12-04 02:43:10","post_date_gmt":"2018-12-04 01:43:10","post_content":"","post_title":"Shaheen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"shaheen","to_ping":"","pinged":"","post_modified":"2018-12-04 02:43:10","post_modified_gmt":"2018-12-04 01:43:10","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/shaheen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":49997,"post_author":"0","post_date":"2018-12-04 05:08:04","post_date_gmt":"2018-12-04 04:08:04","post_content":"","post_title":"EUROPEAN RESPIRATORY JOURNAL","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"european-respiratory-journal","to_ping":"","pinged":"","post_modified":"2018-12-04 05:08:04","post_modified_gmt":"2018-12-04 04:08:04","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/european-respiratory-journal\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\n