{"id":49838,"date":"2005-12-01T00:00:00","date_gmt":"2018-12-04T04:03:30","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plasma-carotenoids-as-biomarkers-of-intake-of-fruits-and-vegetables\/"},"modified":"2018-12-04T05:03:30","modified_gmt":"2018-12-04T04:03:30","slug":"plasma-carotenoids-as-biomarkers-of-intake-of-fruits-and-vegetables","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/plasma-carotenoids-as-biomarkers-of-intake-of-fruits-and-vegetables\/","title":{"rendered":"Plasma carotenoids as biomarkers of intake of fruits and vegetables: individual-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC)"},"content":{"rendered":"<p><strong>Objective<\/strong>: The aim in this study was to assess the association between individual plasma carotenoid levels (alpha-carotene, beta-carotene, lycopene, beta-cryptoxanthin, lutein, zeaxanthin) and fruit and vegetable intakes recorded by a calibrated food questionnaire (FQ) and 24- h dietary recall records (24HDR) in nine different European countries with diverse populations and widely varying intakes of plant foods.<\/p>\n<p><strong>Design<\/strong>: A stratified random subsample of 3089 men and women from nine countries participating in the European Prospective Investigation into Cancer and Nutrition (<span class='tooltipsall tooltip_post_id_80438 classtoolTips80438'>EPIC<\/span>), who had provided blood samples and dietary and other lifestyle information between 1992 and 2000, were included.<\/p>\n<p><strong>Results<\/strong>: beta-Cryptoxanthin was most strongly correlated with total fruits (FQ r = 0.52, 24HDR r = 0.39), lycopene with tomato and tomato products (FQ r = 0.38, 24HDR r = 0.25), and alpha-carotene with intake of root vegetables (r = 0.39) and of total carrots (r = 0.38) for FQ only. Based on diet measured by FQ and adjusting for possible confounding by body mass index (BMI), age, gender, smoking status, alcohol intake, and energy intake, the strongest predictors of individual plasma carotenoid levels were fruits (R-partial(2) = 17.2%) for beta-cryptoxanthin, total carrots (R-partial(2) = 13.4%) and root vegetables (R-partial(2) = 13.3%) for alpha-carotene, and tomato products (R-partial(2) = 13.8%) for lycopene. For 24HDR, the highest R-partial(2) was for fruits in relation to beta-cryptoxanthin (7.9%).<\/p>\n<p><strong>Conclusions<\/strong>: Intakes of specific fruits and vegetables as measured by food questionnaires are good predictors of certain individual plasma carotenoid levels in our multicentre European study. At individual subject levels, FQ measurements of fruits, root vegetables and carrots, and tomato products are, respectively, good predictors of beta-cryptoxanthin, alpha-carotene, and lycopene in plasma.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-49838","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Riboli E (reprint author), Int Agcy Res Canc, Nutr & Hormones Grp, WHO, 150 Cours Albert Thomas, F-69372 Lyon France Int Agcy Res Canc, Nutr & Hormones Grp, WHO, F-69372 Lyon France Natl Canc Inst, Epidemiol Unit, I-20133 Milan Italy Umea Univ, Dept Odontol & Cariol, Umea, Sweden Umea Univ, Dept Nutr Res, Umea, Sweden Lund Univ, Dept Med Surg & Orthopaed, Malmo, Sweden Osped Oncol Reg, Rionero, Italy Sci Inst Tuscany, CSPO, Mol & Nutr Epidemiol Unit, Florence, Italy Univ Turin, Canc Epidemiol Unit, Turin, Italy CPO Piemonte, Turin, Italy Azienda Osped Civile MP Arezzo, Canc Registry, Ragusa, Italy Hlth Council Basque Country, Publ Hlth Off Guipuzkoa, San Sebastian, Spain ICO, Dept Epidemiol, Barcelona, Spain Natl Inst Publ Hlth & Environm, NL-3720 BA Bilthoven Netherlands Aalborg Hosp, Dept Clin Epidemiol, Aalborg, Denmark Aarhus Univ Hosp, Aarhus, Denmark Univ Aarhus, Dept Epidemiol & Social Med, DK-8000 Aarhus Denmark Council Hlth & Social Affairs Murcia, Dept Epidemiol, Murcia, Spain Univ Athens, Sch Med, GR-11527 Athens Greece Danish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark Univ Tromso, Inst Community Med, N-9001 Tromso Norway Inst Publ Hlth Navarra, Pamplona, Spain Inst Gustave Roussy, INSERM, U XR 521, F-94805 Villejuif France CNAM, ISTNA, INSERM, U557, Paris, France Univ Oxford, Radcliffe Infirm, Canc Res UK, Oxford OX1 2JD England MRC, Dunn Human Nutr Unit, Cambridge, England Univ Cambridge, Strangeways Res Lab, Cambridge CB2 1TN England Andalusian Sch Publ Hlth, Granada, Spain German Canc Res Ctr, Div Clin Epidemiol, D-6900 Heidelberg Germany Reg Off Publ Hlth Asturias, Oviedo, Spain Univ Med Ctr, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands German Inst Human Nutr, Potsdam, Germany Hop Edouard Herriot, Biochem Lab, Lyon, France E-mail Addresses: nth@iarc.fr","annee":"2005","mois":"12","numero":"59:12","page":"1387-1396","auteurs":[{"ID":5356,"post_author":"0","post_date":"2018-12-03 17:27:00","post_date_gmt":"2018-12-03 16:27:00","post_content":"","post_title":"Ailsa A Welch","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ailsa-a-welch","to_ping":"","pinged":"","post_modified":"2018-12-03 17:27:00","post_modified_gmt":"2018-12-03 16:27:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ailsa-a-welch\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":8771,"post_author":"0","post_date":"2018-12-03 18:03:53","post_date_gmt":"2018-12-03 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