{"id":49474,"date":"2005-10-01T00:00:00","date_gmt":"2018-12-04T03:57:34","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/kinetics-of-14c-distribution-after-tracer-dose-of-14c-lutein\/"},"modified":"2018-12-04T04:57:34","modified_gmt":"2018-12-04T03:57:34","slug":"kinetics-of-14c-distribution-after-tracer-dose-of-14c-lutein","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/kinetics-of-14c-distribution-after-tracer-dose-of-14c-lutein\/","title":{"rendered":"Kinetics of 14c distribution after tracer dose of 14c-lutein in an adult woman."},"content":{"rendered":"

Lutein is an oxygenated carotenoid (xanthophyll) found in dark green leafy vegetables. High intakes of lutein may lower the risk of age-related macular degeneration. Current understanding of human lutein metabolism as it might occur in vivo is incomplete. Therefore, we conducted a feasibility study where we dosed a normal adult woman with 14C-lutein (125 nmol, 36 nCi 14C), dissolved in olive oil (0.5 g\/kg body weight) and mixed in a banana shake. Blood, urine, and feces collected before the dose was administered served to establish baseline values. Thereafter, blood was collected for 63 d following the dose, while feces and urine were collected for 2 wk post-dose. The 14C contents in plasma, urine, and feces were measured by accelerator MS. The 14C first appeared in plasma 1 h after dosing and reached its highest level, approximately2.08% of dose\/L plasma, at 14 h post-dose. The plasma pattern of 14C did not include a chylomicrons\/VLDL (intestinal) peak like that when the same subject received 14C-beta-carotene (a previous test), suggesting that lutein was handled differently from beta-carotene by plasma lipoproteins. Lutein had an elimination half-life (t1\/2) of approximately10 d. Forty-five percent of the dose of 14C was eliminated in feces and 10% in urine in the first 2 d after dosing. Quantifying human lutein metabolism is a fertile area for future research.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-49474","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Nutrition, University of California Davis, 95616-8669, USA.","annee":"2005","mois":"10","numero":"40:10","page":"1069-73","auteurs":[{"ID":26155,"post_author":"0","post_date":"2018-12-03 22:33:45","post_date_gmt":"2018-12-03 21:33:45","post_content":"","post_title":"Fabiana F De Moura","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"fabiana-f-de-moura","to_ping":"","pinged":"","post_modified":"2018-12-03 22:33:45","post_modified_gmt":"2018-12-03 21:33:45","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/fabiana-f-de-moura\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":44105,"post_author":"0","post_date":"2018-12-04 03:17:47","post_date_gmt":"2018-12-04 02:17:47","post_content":"","post_title":"Bezuidenhout","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"bezuidenhout","to_ping":"","pinged":"","post_modified":"2018-12-04 03:17:47","post_modified_gmt":"2018-12-04 02:17:47","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/bezuidenhout\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":49471,"post_author":"0","post_date":"2018-12-04 04:57:32","post_date_gmt":"2018-12-04 03:57:32","post_content":"","post_title":"Getachew","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"getachew","to_ping":"","pinged":"","post_modified":"2018-12-04 04:57:32","post_modified_gmt":"2018-12-04 03:57:32","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/getachew\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":49472,"post_author":"0","post_date":"2018-12-04 04:57:33","post_date_gmt":"2018-12-04 03:57:33","post_content":"","post_title":"Hickenbottom","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"hickenbottom","to_ping":"","pinged":"","post_modified":"2018-12-04 04:57:33","post_modified_gmt":"2018-12-04 03:57:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/hickenbottom\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":49473,"post_author":"0","post_date":"2018-12-04 04:57:33","post_date_gmt":"2018-12-04 03:57:33","post_content":"","post_title":"Clifford","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"clifford-2","to_ping":"","pinged":"","post_modified":"2018-12-04 04:57:33","post_modified_gmt":"2018-12-04 03:57:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/clifford-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":40190,"post_author":"0","post_date":"2018-12-04 02:10:22","post_date_gmt":"2018-12-04 01:10:22","post_content":"","post_title":"LIPIDS","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lipids","to_ping":"","pinged":"","post_modified":"2018-12-04 02:10:22","post_modified_gmt":"2018-12-04 01:10:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/lipids\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nKinetics of 14c distribution after tracer dose of 14c-lutein in an adult woman. - Aprifel<\/title>\n<meta name=\"description\" content=\"Kinetics of 14c distribution after tracer dose of 14c-lutein in an adult woman. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kinetics of 14c distribution after tracer dose of 14c-lutein in an adult woman.\" \/>\n<meta property=\"og:description\" content=\"Kinetics of 14c distribution after tracer dose of 14c-lutein in an adult woman.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/kinetics-of-14c-distribution-after-tracer-dose-of-14c-lutein\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/kinetics-of-14c-distribution-after-tracer-dose-of-14c-lutein\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/kinetics-of-14c-distribution-after-tracer-dose-of-14c-lutein\/\",\"name\":\"Kinetics of 14c distribution after tracer dose of 14c-lutein in an adult woman. - 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