{"id":49398,"date":"2006-05-01T00:00:00","date_gmt":"2018-12-04T03:56:14","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-intake-and-the-risk-of-stomach-and-oesophagus\/"},"modified":"2018-12-04T04:56:14","modified_gmt":"2018-12-04T03:56:14","slug":"fruit-and-vegetable-intake-and-the-risk-of-stomach-and-oesophagus","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-intake-and-the-risk-of-stomach-and-oesophagus\/","title":{"rendered":"Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-Eurgast)."},"content":{"rendered":"<p>It is considered that fruit and vegetable (F&amp;V) protect against oesophagus and gastric cancer (GC). However, 2 recent meta-analyses suggest that the strength of association on GC seems to be weaker for vegetables than for fruit and weaker in cohort than in case-control studies. No evidence exists from cohort studies about adenocarcinoma of oesophagus (ACO). In 521,457 men and women participating in the <span class='tooltipsall tooltip_post_id_80438 classtoolTips80438'>EPIC<\/span> cohort in 10 European countries, information of diet and lifestyle was collected at baseline. After an average of 6.5 years of follow-up, a total of 330 GC and 65 ACO, confirmed and classified by a panel of pathologists, was used for the analysis. We examined the relation between F&amp;V intake and GC and ACO. A calibration study in a sub-sample was used to control diet measurement errors. In a sub-sample of cases and a random sample of controls, antibodies against Helicobacter pylori (Hp) were measured and interactions with F&amp;V were examined in a nested case-control study. We observed no association with total vegetable intake or specific groups of vegetables and GC risk, except for the intestinal type, where a negative association is possible regarding total vegetable (calibrated HR 0.66; 95% CI 0.35-1.22 per 100 g increase) and onion and garlic intake (calibrated HR 0.70; 95% CI 0.38-1.29 per 10 g increase). No evidence of association between fresh fruit intake and GC risk was observed. We found a negative but non significant association between citrus fruit intake and the cardia site (calibrated HR 0.77; 95% CI 0.47-1.22 per 100 g increase) while no association was observed with the non-cardia site. Regarding ACO, we found a non significant negative association for vegetable intake and for citrus intake (calibrated HRs 0.72; 95% CI 0.32-1.64 and 0.77; 95% CI 0.46-1.28 per 100 and 50 g increase, respectively). It seems that Hp infection does not modify the effect of F&amp;V intake. Our study supports a possible protective role of vegetable intake in the intestinal type of GC and the ACO. Citrus fruit consumption may have a role in the protection against cardia GC and ACO.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-49398","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Epidemiology, Catalan Institute of Oncology, Barcelona (ICO-IDIBELL), Spain.","annee":"2006","mois":"5","numero":"118:10","page":"2559-2566","auteurs":[{"ID":1330,"post_author":"0","post_date":"2018-12-03 15:58:24","post_date_gmt":"2018-12-03 14:58:24","post_content":"","post_title":"Heiner Boeing","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"heiner-boeing","to_ping":"","pinged":"","post_modified":"2018-12-03 15:58:24","post_modified_gmt":"2018-12-03 14:58:24","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/heiner-boeing\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":36805,"post_author":"0","post_date":"2018-12-04 01:06:57","post_date_gmt":"2018-12-04 00:06:57","post_content":"","post_title":"C A Gonzalez","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"c-a-gonzalez","to_ping":"","pinged":"","post_modified":"2018-12-04 01:06:57","post_modified_gmt":"2018-12-04 00:06:57","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/c-a-gonzalez\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":8773,"post_author":"0","post_date":"2018-12-03 18:03:54","post_date_gmt":"2018-12-03 17:03:54","post_content":"","post_title":"H Bas 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17:03:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/antonio-agudo\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":49397,"post_author":"0","post_date":"2018-12-04 04:56:12","post_date_gmt":"2018-12-04 03:56:12","post_content":"","post_title":"Ceroti","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ceroti","to_ping":"","pinged":"","post_modified":"2018-12-04 04:56:12","post_modified_gmt":"2018-12-04 03:56:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ceroti\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":31167,"post_author":"0","post_date":"2018-12-03 23:41:30","post_date_gmt":"2018-12-03 22:41:30","post_content":"","post_title":"Mark R Schulz","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"mark-r-schulz","to_ping":"","pinged":"","post_modified":"2018-12-03 23:41:30","post_modified_gmt":"2018-12-03 22:41:30","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/mark-r-schulz\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":24905,"post_author":"0","post_date":"2018-12-03 22:06:09","post_date_gmt":"2018-12-03 21:06:09","post_content":"","post_title":"Guillem Pera","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"guillem-pera","to_ping":"","pinged":"","post_modified":"2018-12-03 22:06:09","post_modified_gmt":"2018-12-03 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