{"id":48428,"date":"2006-06-01T00:00:00","date_gmt":"2018-12-04T03:33:43","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/association-between-consumption-of-cruciferous-vegetables\/"},"modified":"2018-12-04T04:33:43","modified_gmt":"2018-12-04T03:33:43","slug":"association-between-consumption-of-cruciferous-vegetables","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/association-between-consumption-of-cruciferous-vegetables\/","title":{"rendered":"Association between consumption of cruciferous vegetables and condiments and excretion in urine of isothiocyanate mercapturic acids"},"content":{"rendered":"<p>Abstract: A high intake of cruciferous vegetables is associated with a reduced risk of cancer and cardiovascular diseases. This protective effect has been linked to isothiocyanates, enzymatic hydrolysis products of glucosinolates. In this study, the metabolic fate of glucosinolates and isothiocyanates after ingestion of 19 different cruciferous vegetables was studied in three male subjects. After the consumption of 13 cruciferous vegetables ( glucosinolate content, 0.01-0.94 mmol\/kg) and six condiments ( isothiocyanate content, 0.06-49.3 mmol\/kg), eight different isothiocyanate mercapturic acids were determined in urine samples. Excretion levels after the consumption of raw vegetables and condiments were higher (bioavailability, 8.2-113%) as compared to cooked vegetables (bioavailability, 1.8-43%), but the excretion rate was similar (t(1\/2) = 2.1-3.9 h). Isothiocyanates in urine remain longer at a nonzero level after the consumption of glucosinolates from cooked vegetables, as compared to raw vegetables and condiments, and maximal levels in urine were reached about 4 h later. Isothiocyanate mercapturic acids can be used as a biomarker to reflect the active dose of isothiocyanates absorbed.<br \/>\nAuthor Keywords: cruciferous vegetables; glucosinolates; HPLC-MS analysis; kinetics; biomarker<br \/>\nKeyWords Plus: BENZYL ISOTHIOCYANATE; BRASSICA VEGETABLES; QUANTITATIVE-DETERMINATION; CYSTEINE CONJUGATE; CANCER PREVENTION; METABOLISM; HUMANS; BIOMARKER; FRUIT; IDENTIFICATION <\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-48428","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Addresses: Vaes WHJ (reprint author), TNO Qual Life, Business Unit Analyt Res, POB 360, NL-3700 AJ Zeist Netherlands\r\nTNO Qual Life, Business Unit Analyt Res, NL-3700 AJ Zeist Netherlands \r\nE-mail Addresses: wouter.vaes@tno.nl \r\n\r\nPublisher: AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, http:\/\/pubs.acs.org \r\nDiscipline: AGRICULTURAL CHEMISTRY\r\nCHEMISTRY & ANALYSIS\r\n\r\n","annee":"2006","mois":"6","numero":"54:15","page":"5350-5358","auteurs":[{"ID":48423,"post_author":"0","post_date":"2018-12-04 04:33:39","post_date_gmt":"2018-12-04 03:33:39","post_content":"","post_title":"Vaes","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"vaes","to_ping":"","pinged":"","post_modified":"2018-12-04 04:33:39","post_modified_gmt":"2018-12-04 03:33:39","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/vaes\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":48424,"post_author":"0","post_date":"2018-12-04 04:33:40","post_date_gmt":"2018-12-04 03:33:40","post_content":"","post_title":"Van Den Berg","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"van-den-berg-3","to_ping":"","pinged":"","post_modified":"2018-12-04 04:33:40","post_modified_gmt":"2018-12-04 03:33:40","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/van-den-berg-3\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":48425,"post_author":"0","post_date":"2018-12-04 04:33:41","post_date_gmt":"2018-12-04 03:33:41","post_content":"","post_title":"Vermeulen","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"vermeulen","to_ping":"","pinged":"","post_modified":"2018-12-04 04:33:41","post_modified_gmt":"2018-12-04 03:33:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/vermeulen\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":48426,"post_author":"0","post_date":"2018-12-04 04:33:41","post_date_gmt":"2018-12-04 03:33:41","post_content":"","post_title":"Freidig","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"freidig","to_ping":"","pinged":"","post_modified":"2018-12-04 04:33:41","post_modified_gmt":"2018-12-04 03:33:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/freidig\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":48427,"post_author":"0","post_date":"2018-12-04 04:33:42","post_date_gmt":"2018-12-04 03:33:42","post_content":"","post_title":"Van Bladeren","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"van-bladeren","to_ping":"","pinged":"","post_modified":"2018-12-04 04:33:42","post_modified_gmt":"2018-12-04 03:33:42","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/van-bladeren\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1648,"post_author":"0","post_date":"2018-12-03 16:01:16","post_date_gmt":"2018-12-03 15:01:16","post_content":"","post_title":"Journal of agricultural and food chemistry","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"journal-of-agricultural-and-food-chemistry","to_ping":"","pinged":"","post_modified":"2018-12-03 16:01:16","post_modified_gmt":"2018-12-03 15:01:16","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/journal-of-agricultural-and-food-chemistry\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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