{"id":48336,"date":"2006-05-01T00:00:00","date_gmt":"2018-12-04T03:32:00","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/associations-of-vitamin-c-status-fruit-and-vegetable-intakes\/"},"modified":"2018-12-04T04:32:00","modified_gmt":"2018-12-04T03:32:00","slug":"associations-of-vitamin-c-status-fruit-and-vegetable-intakes","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/associations-of-vitamin-c-status-fruit-and-vegetable-intakes\/","title":{"rendered":"Associations of vitamin c status, fruit and vegetable intakes, and markers of inflammation and hemostasis."},"content":{"rendered":"<p>BACKGROUND: It has been suggested that a high dietary intake and high circulating concentrations of vitamin C may protect against ischemic heart disease. OBJECTIVES: The objective was to examine the associations between dietary and plasma vitamin C concentrations, fruit and vegetable intakes, and markers of inflammation and hemostasis associated with cardiovascular disease in older men free of cardiovascular disease. DESIGN: This cross-sectional study examined 3258 men aged 60-79 y with no physician diagnosis of myocardial infarction, stroke, or diabetes and who were drawn from general practices in 24 British towns. Fruit and vegetable intakes and dietary vitamin C were assessed by using a food-frequency questionnaire. RESULTS: Plasma vitamin C, fruit intake, and dietary vitamin C intake were significantly and inversely associated with mean concentrations of C-reactive protein, an acute phase reactant, and tissue plasminogen activator (t-PA) antigen, a marker of endothelial dysfunction, even after adjustment for confounders. Vegetable intake was correlated significantly (inversely) only with t-PA. For plasma vitamin C (highest versus lowest quartile), the adjusted odds of elevated C-reactive protein and t-PA (highest tertile versus lowest tertile) were 0.56 (95% CI: 0.44, 0.71) and 0.79 (0.62, 1.00); for fruit intake, the corresponding odds ratios were 0.76 (0.60, 0.95) and 0.76 (0.61, 0.95). Plasma (but not dietary) vitamin C also showed inverse associations with both fibrinogen concentrations and blood viscosity. No associations were seen with von Willebrand factor or factor VIII. CONCLUSION: The findings suggest that vitamin C has antiinflammatory effects and is associated with lower endothelial dysfunction in men with no history of cardiovascular disease or diabetes.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-48336","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom. goya@pcps.ucl.ac.uk","annee":"2006","mois":"5","numero":"83:3","page":"567-74","auteurs":[{"ID":16891,"post_author":"0","post_date":"2018-12-03 19:44:33","post_date_gmt":"2018-12-03 18:44:33","post_content":"","post_title":"Peter H Whincup","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"peter-h-whincup","to_ping":"","pinged":"","post_modified":"2018-12-03 19:44:33","post_modified_gmt":"2018-12-03 18:44:33","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/peter-h-whincup\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":16895,"post_author":"0","post_date":"2018-12-03 19:44:35","post_date_gmt":"2018-12-03 18:44:35","post_content":"","post_title":"S Goya Wannamethee","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"s-goya-wannamethee","to_ping":"","pinged":"","post_modified":"2018-12-03 19:44:35","post_modified_gmt":"2018-12-03 18:44:35","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/s-goya-wannamethee\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":48333,"post_author":"0","post_date":"2018-12-04 04:31:59","post_date_gmt":"2018-12-04 03:31:59","post_content":"","post_title":"Rumley","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"rumley","to_ping":"","pinged":"","post_modified":"2018-12-04 04:31:59","post_modified_gmt":"2018-12-04 03:31:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/rumley\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":48334,"post_author":"0","post_date":"2018-12-04 04:31:59","post_date_gmt":"2018-12-04 03:31:59","post_content":"","post_title":"Lowe","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lowe-3","to_ping":"","pinged":"","post_modified":"2018-12-04 04:31:59","post_modified_gmt":"2018-12-04 03:31:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/lowe-3\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":48335,"post_author":"0","post_date":"2018-12-04 04:32:00","post_date_gmt":"2018-12-04 03:32:00","post_content":"","post_title":"Bruckdorfer","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"bruckdorfer","to_ping":"","pinged":"","post_modified":"2018-12-04 04:32:00","post_modified_gmt":"2018-12-04 03:32:00","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/bruckdorfer\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":44192,"post_author":"0","post_date":"2018-12-04 03:19:18","post_date_gmt":"2018-12-04 02:19:18","post_content":"","post_title":"AMERICAN JOURNAL OF CLINICAL NUTRITION","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"american-journal-of-clinical-nutrition","to_ping":"","pinged":"","post_modified":"2018-12-04 03:19:18","post_modified_gmt":"2018-12-04 02:19:18","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/american-journal-of-clinical-nutrition\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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