{"id":48164,"date":"2006-09-01T00:00:00","date_gmt":"2018-12-04T03:28:53","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/"},"modified":"2018-12-04T04:28:53","modified_gmt":"2018-12-04T03:28:53","slug":"fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/","title":{"rendered":"Fruit and vegetable juices and alzheimer&rsquo;s disease: the kame project."},"content":{"rendered":"<p>BACKGROUND: Growing evidence suggests that oxidative damage caused by the beta-amyloid peptide in the pathogenesis of Alzheimer&rsquo;s disease may be hydrogen peroxide mediated. Many polyphenols, the most abundant dietary antioxidants, possess stronger neuroprotection against hydrogen peroxide than antioxidant vitamins. METHODS: We tested whether consumption of fruit and vegetable juices, containing a high concentration of polyphenols, decreases the risk of incident probable Alzheimer&rsquo;s disease in the Kame Project cohort, a population-based prospective study of 1836 Japanese Americans in King County, Washington, who were dementia-free at baseline (1992-1994) and were followed through 2001. RESULTS: After adjustment for potential confounders, the hazard ratio for probable Alzheimer&rsquo;s disease was 0.24 (95% confidence interval [CI], 0.09-0.61) comparing subjects who drank juices at least 3 times per week with those who drank less often than once per week with a hazard ratio of 0.84 (95% CI, 0.31-2.29) for those drinking juices 1 to 2 times per week (P for trend &lt; .01). This inverse association tended to be more pronounced among those with an apolipoprotein Eepsilon-4 allele and those who were not physically active. Conversely, no association was observed for dietary intake of vitamins E, C, or beta-carotene or tea consumption. CONCLUSIONS: Fruit and vegetable juices may play an important role in delaying the onset of Alzheimer&#039;s disease, particularly among those who are at high risk for the disease. These results may lead to a new avenue of inquiry in the prevention of Alzheimer&#039;s disease.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-48164","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Medicine, Division of General Internal Medicine and Public Health, Vanderbilt Center for Health Services Research, Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, Tenn, USA. qi.dai@vanderbilt.edu","annee":"2006","mois":"9","numero":"119:9","page":"751-9","auteurs":[{"ID":43099,"post_author":"0","post_date":"2018-12-04 03:01:31","post_date_gmt":"2018-12-04 02:01:31","post_content":"","post_title":"Dai","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"dai-3","to_ping":"","pinged":"","post_modified":"2018-12-04 03:01:31","post_modified_gmt":"2018-12-04 02:01:31","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/dai-3\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":48162,"post_author":"0","post_date":"2018-12-04 04:28:52","post_date_gmt":"2018-12-04 03:28:52","post_content":"","post_title":"Borenstein","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"borenstein","to_ping":"","pinged":"","post_modified":"2018-12-04 04:28:52","post_modified_gmt":"2018-12-04 03:28:52","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/borenstein\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":36500,"post_author":"0","post_date":"2018-12-04 01:01:17","post_date_gmt":"2018-12-04 00:01:17","post_content":"","post_title":"Wu","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"wu-3","to_ping":"","pinged":"","post_modified":"2018-12-04 01:01:17","post_modified_gmt":"2018-12-04 00:01:17","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/wu-3\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":38572,"post_author":"0","post_date":"2018-12-04 01:39:36","post_date_gmt":"2018-12-04 00:39:36","post_content":"","post_title":"Jackson","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"jackson-2","to_ping":"","pinged":"","post_modified":"2018-12-04 01:39:36","post_modified_gmt":"2018-12-04 00:39:36","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/jackson-2\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":48163,"post_author":"0","post_date":"2018-12-04 04:28:53","post_date_gmt":"2018-12-04 03:28:53","post_content":"","post_title":"Larson","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"larson","to_ping":"","pinged":"","post_modified":"2018-12-04 04:28:53","post_modified_gmt":"2018-12-04 03:28:53","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/larson\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":33794,"post_author":"0","post_date":"2018-12-04 00:17:55","post_date_gmt":"2018-12-03 23:17:55","post_content":"","post_title":"Am J Med.","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"am-j-med","to_ping":"","pinged":"","post_modified":"2018-12-04 00:17:55","post_modified_gmt":"2018-12-03 23:17:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/am-j-med\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Fruit and vegetable juices and alzheimer&#039;s disease: the kame project. - Aprifel<\/title>\n<meta name=\"description\" content=\"Fruit and vegetable juices and alzheimer&#039;s disease: the kame project. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fruit and vegetable juices and alzheimer&#039;s disease: the kame project.\" \/>\n<meta property=\"og:description\" content=\"Fruit and vegetable juices and alzheimer&#039;s disease: the kame project.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/\",\"name\":\"Fruit and vegetable juices and alzheimer's disease: the kame project. - Aprifel\",\"isPartOf\":{\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\"},\"datePublished\":\"2018-12-04T03:28:53+00:00\",\"dateModified\":\"2018-12-04T03:28:53+00:00\",\"description\":\"Fruit and vegetable juices and alzheimer's disease: the kame project. - Aprifel\",\"breadcrumb\":{\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.aprifel.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R\u00e9sum\u00e9s\",\"item\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Fruit and vegetable juices and alzheimer&rsquo;s disease: the kame project.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\",\"url\":\"https:\/\/www.aprifel.com\/fr\/\",\"name\":\"Aprifel\",\"description\":\"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Fruit and vegetable juices and alzheimer's disease: the kame project. - Aprifel","description":"Fruit and vegetable juices and alzheimer's disease: the kame project. - Aprifel","robots":{"index":"noindex","follow":"follow"},"og_locale":"fr_FR","og_type":"article","og_title":"Fruit and vegetable juices and alzheimer's disease: the kame project.","og_description":"Fruit and vegetable juices and alzheimer's disease: the kame project.","og_url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/","og_site_name":"Aprifel","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/","url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/","name":"Fruit and vegetable juices and alzheimer's disease: the kame project. - Aprifel","isPartOf":{"@id":"https:\/\/www.aprifel.com\/fr\/#website"},"datePublished":"2018-12-04T03:28:53+00:00","dateModified":"2018-12-04T03:28:53+00:00","description":"Fruit and vegetable juices and alzheimer's disease: the kame project. - Aprifel","breadcrumb":{"@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/fruit-and-vegetable-juices-and-alzheimer-s-disease-the-kame\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.aprifel.com\/fr\/"},{"@type":"ListItem","position":2,"name":"R\u00e9sum\u00e9s","item":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/"},{"@type":"ListItem","position":3,"name":"Fruit and vegetable juices and alzheimer&rsquo;s disease: the kame project."}]},{"@type":"WebSite","@id":"https:\/\/www.aprifel.com\/fr\/#website","url":"https:\/\/www.aprifel.com\/fr\/","name":"Aprifel","description":"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"}]}},"_links":{"self":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume\/48164"}],"collection":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume"}],"about":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/types\/resume"}],"wp:attachment":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/media?parent=48164"}],"wp:term":[{"taxonomy":"mots_cles","embeddable":true,"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/mots_cles?post=48164"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}