{"id":46224,"date":"2007-02-01T00:00:00","date_gmt":"2018-12-04T02:53:47","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/carotenoids-as-protection-against-sarcopenia-in-older-adults\/"},"modified":"2018-12-04T03:53:47","modified_gmt":"2018-12-04T02:53:47","slug":"carotenoids-as-protection-against-sarcopenia-in-older-adults","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/carotenoids-as-protection-against-sarcopenia-in-older-adults\/","title":{"rendered":"Carotenoids as protection against sarcopenia in older adults."},"content":{"rendered":"

Sarcopenia, or loss of muscle mass and strength, plays a major role in the disablement process in older adults and increases the risk of impaired physical performance, falls, physical disability, frailty, and death. Oxidative stress is a major mechanism implicated in the pathogenesis of sarcopenia; aging muscle shows increased oxidative damage to DNA, protein, and lipids. Carotenoids quench free radicals, reduce damage from reactive oxygen species, and appear to modulate redox-sensitive transcription factors such as NF-kappaB that are involved in the upregulation of IL-6 and other proinflammatory cytokines. Recent epidemiological studies in community-dwelling older adults show that low serum\/plasma carotenoids are independently associated with low skeletal muscle strength and the development of walking disability. These observations are consistent with a growing number of studies showing that a diet with high intake of fruits and vegetables is associated with a reduced risk of inflammation, hypertension, diabetes, cardiovascular disease, and mortality.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-46224","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. rdsemba@jhmi.edu\r\n","annee":"2007","mois":"2","numero":"458:2","page":"141-5","auteurs":[{"ID":39925,"post_author":"0","post_date":"2018-12-04 02:05:44","post_date_gmt":"2018-12-04 01:05:44","post_content":"","post_title":"Semba","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"semba","to_ping":"","pinged":"","post_modified":"2018-12-04 02:05:44","post_modified_gmt":"2018-12-04 01:05:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/semba\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":43490,"post_author":"0","post_date":"2018-12-04 03:07:51","post_date_gmt":"2018-12-04 02:07:51","post_content":"","post_title":"Lauretani","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"lauretani","to_ping":"","pinged":"","post_modified":"2018-12-04 03:07:51","post_modified_gmt":"2018-12-04 02:07:51","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/lauretani\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":28908,"post_author":"0","post_date":"2018-12-03 23:12:05","post_date_gmt":"2018-12-03 22:12:05","post_content":"","post_title":"Luigi Ferrucci","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"luigi-ferrucci","to_ping":"","pinged":"","post_modified":"2018-12-03 23:12:05","post_modified_gmt":"2018-12-03 22:12:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/luigi-ferrucci\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":5122,"post_author":"0","post_date":"2018-12-03 17:24:29","post_date_gmt":"2018-12-03 16:24:29","post_content":"","post_title":"ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"archives-of-biochemistry-and-biophysics","to_ping":"","pinged":"","post_modified":"2018-12-03 17:24:29","post_modified_gmt":"2018-12-03 16:24:29","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/archives-of-biochemistry-and-biophysics\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nCarotenoids as protection against sarcopenia in older adults. - 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