{"id":45731,"date":"2007-02-01T00:00:00","date_gmt":"2018-12-04T02:45:43","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/bioavailability-of-food-folates-is-80-of-that-of-folic-acid\/"},"modified":"2018-12-04T03:45:43","modified_gmt":"2018-12-04T02:45:43","slug":"bioavailability-of-food-folates-is-80-of-that-of-folic-acid","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/bioavailability-of-food-folates-is-80-of-that-of-folic-acid\/","title":{"rendered":"Bioavailability of food folates is 80% of that of folic acid"},"content":{"rendered":"<p>BACKGROUND: The bioavailability of natural food folates is lower than that of synthetic folic acid, but no agreement exists as to the extent of the difference. OBJECTIVE: In a 4-wk dietary intervention study, we determined the aggregate bioavailability of food folates from fruit, vegetables, and liver relative to that of folic acid. DESIGN: Seventy-two healthy adults were randomly divided into 4 treatment groups. Group A (n = 29) received a high-folate diet with 369 mug food folate\/d and a placebo capsule; groups B, C, and D (n = 14 or 15) received a low-folate diet with 73 microg food folate\/d and folic acid capsules. These capsules contained 92 microg folic acid\/d for group B, 191 microg for group C, and 289 microg for group D. In addition, all 72 subjects daily ingested a capsule with 58 microg [(13)C(11)]-labeled folic acid. We measured the percentage of [(13)C(11)]-labeled folate in plasma folate at the end of the intervention and ascertained the changes in serum folate concentrations over the 4 wk of the intervention. RESULTS: Bioavailability of food folate relative to that of folic acid was 78% (95% CI: 48%, 108%) according to [(13)C(11)]-labeled folate and 85% (52%, 118%) according to changes in serum folate concentrations. CONCLUSIONS: The aggregate bioavailability of folates from fruit, vegetables, and liver is approximately 80% of that of folic acid. The consumption of a diet rich in food folate can improve the folate status of a population more efficiently than is generally assumed.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-45731","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Wageningen Centre for Food Sciences, Wageningen, Netherlands. renate.winkels@wur.nl","annee":"2007","mois":"2","numero":"85:2","page":"465-73","auteurs":[{"ID":45728,"post_author":"0","post_date":"2018-12-04 03:45:41","post_date_gmt":"2018-12-04 02:45:41","post_content":"","post_title":"Katan","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"katan","to_ping":"","pinged":"","post_modified":"2018-12-04 03:45:41","post_modified_gmt":"2018-12-04 02:45:41","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/katan\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":45729,"post_author":"0","post_date":"2018-12-04 03:45:42","post_date_gmt":"2018-12-04 02:45:42","post_content":"","post_title":"Winkels","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"winkels","to_ping":"","pinged":"","post_modified":"2018-12-04 03:45:42","post_modified_gmt":"2018-12-04 02:45:42","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/winkels\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":45730,"post_author":"0","post_date":"2018-12-04 03:45:42","post_date_gmt":"2018-12-04 02:45:42","post_content":"","post_title":"Siebelink","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"siebelink","to_ping":"","pinged":"","post_modified":"2018-12-04 03:45:42","post_modified_gmt":"2018-12-04 02:45:42","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/siebelink\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":44257,"post_author":"0","post_date":"2018-12-04 03:20:18","post_date_gmt":"2018-12-04 02:20:18","post_content":"","post_title":"Verhoef","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"verhoef","to_ping":"","pinged":"","post_modified":"2018-12-04 03:20:18","post_modified_gmt":"2018-12-04 02:20:18","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/verhoef\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":7967,"post_author":"0","post_date":"2018-12-03 17:54:49","post_date_gmt":"2018-12-03 16:54:49","post_content":"","post_title":"Ingeborg A Brouwer","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ingeborg-a-brouwer","to_ping":"","pinged":"","post_modified":"2018-12-03 17:54:49","post_modified_gmt":"2018-12-03 16:54:49","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ingeborg-a-brouwer\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":44192,"post_author":"0","post_date":"2018-12-04 03:19:18","post_date_gmt":"2018-12-04 02:19:18","post_content":"","post_title":"AMERICAN JOURNAL OF CLINICAL NUTRITION","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"american-journal-of-clinical-nutrition","to_ping":"","pinged":"","post_modified":"2018-12-04 03:19:18","post_modified_gmt":"2018-12-04 02:19:18","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/american-journal-of-clinical-nutrition\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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