{"id":45531,"date":"2007-01-01T00:00:00","date_gmt":"2018-12-04T02:43:00","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/weight-change-weight-cycling-and-mortality-in-the-erfort-male\/"},"modified":"2018-12-04T03:43:00","modified_gmt":"2018-12-04T02:43:00","slug":"weight-change-weight-cycling-and-mortality-in-the-erfort-male","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/weight-change-weight-cycling-and-mortality-in-the-erfort-male\/","title":{"rendered":"Weight change, weight cycling and mortality in the erfort male cohort study"},"content":{"rendered":"<p>OBJECTIVE: To investigate the effect of weight change and weight fluctuations on all-cause-mortality in men. METHODS: Within a prospective population-based cohort of 1,160 men aged 40-59 years at recruitment, complete weight change patterns from baseline and three follow-up examinations during a period of 15 years of follow-up was used to categorize the 505 men into stable obese, stable non-obese, weight gain, weight loss and weight fluctuation groups. For these men (age range: 55-74 years at start time of survival analysis) further survival was analyzed during the subsequent 15 years. RESULTS: Overall, 183 deaths were observed among the 505 men. Only weight fluctuations had a clear significant impact on all-cause mortality. Adjusted hazard rate ratio (HRR (95%-CI)) was 1.86 (1.31-2.66) after adjustment for age group, pre-existing cardiovascular disease or diabetes mellitus, smoking and socio-economic status. The risk rate due to weight loss was borderline significant (HRR = 1.81 (0.99-3.31)). Risk of death due to weight gain (HRR = 1.15 (0.70-1.88)) or stable obesity (HRR = 1.16 (0.69-1.94)), however, were not significantly increased compared to men staying non-obese for the first 15 years after cohort recruitment. CONCLUSION: Weight fluctuations are a major risk factor for all-cause mortality in middle aged men. Moreover, stable obesity does not increase further mortality in men aged 55-74 years in long-term follow-up.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-45531","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Institute of Epidemiology, GSF-National Research Center for Environment and Health, Ingolstaedter Landstrasse 1, 85764, Neuherberg, Germany. peter.rzehak@gsf.de","annee":"2007","mois":"0","numero":"22:10","page":"665-73","auteurs":[{"ID":34699,"post_author":"0","post_date":"2018-12-04 00:33:37","post_date_gmt":"2018-12-03 23:33:37","post_content":"","post_title":"Heinrich","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"heinrich","to_ping":"","pinged":"","post_modified":"2018-12-04 00:33:37","post_modified_gmt":"2018-12-03 23:33:37","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/heinrich\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":8515,"post_author":"0","post_date":"2018-12-03 18:01:03","post_date_gmt":"2018-12-03 17:01:03","post_content":"","post_title":"Peter Rzehak","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"peter-rzehak","to_ping":"","pinged":"","post_modified":"2018-12-03 18:01:03","post_modified_gmt":"2018-12-03 17:01:03","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/peter-rzehak\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":45527,"post_author":"0","post_date":"2018-12-04 03:42:58","post_date_gmt":"2018-12-04 02:42:58","post_content":"","post_title":"Meisinger","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"meisinger","to_ping":"","pinged":"","post_modified":"2018-12-04 03:42:58","post_modified_gmt":"2018-12-04 02:42:58","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/meisinger\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":45528,"post_author":"0","post_date":"2018-12-04 03:42:58","post_date_gmt":"2018-12-04 02:42:58","post_content":"","post_title":"Woelke","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"woelke","to_ping":"","pinged":"","post_modified":"2018-12-04 03:42:58","post_modified_gmt":"2018-12-04 02:42:58","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/woelke\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":45529,"post_author":"0","post_date":"2018-12-04 03:42:59","post_date_gmt":"2018-12-04 02:42:59","post_content":"","post_title":"Brasche","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"brasche","to_ping":"","pinged":"","post_modified":"2018-12-04 03:42:59","post_modified_gmt":"2018-12-04 02:42:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/brasche\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":45530,"post_author":"0","post_date":"2018-12-04 03:42:59","post_date_gmt":"2018-12-04 02:42:59","post_content":"","post_title":"Strube","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"strube","to_ping":"","pinged":"","post_modified":"2018-12-04 03:42:59","post_modified_gmt":"2018-12-04 02:42:59","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/strube\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":3458,"post_author":"0","post_date":"2018-12-03 17:05:49","post_date_gmt":"2018-12-03 16:05:49","post_content":"","post_title":"European journal of epidemiology","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"european-journal-of-epidemiology","to_ping":"","pinged":"","post_modified":"2018-12-03 17:05:49","post_modified_gmt":"2018-12-03 16:05:49","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/european-journal-of-epidemiology\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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