{"id":45116,"date":"2008-04-01T00:00:00","date_gmt":"2018-12-04T02:36:57","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/soy-protein-intake-cardiorenal-indices-and-c-reactive-protein\/"},"modified":"2018-12-04T03:36:57","modified_gmt":"2018-12-04T02:36:57","slug":"soy-protein-intake-cardiorenal-indices-and-c-reactive-protein","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/soy-protein-intake-cardiorenal-indices-and-c-reactive-protein\/","title":{"rendered":"Soy protein intake, cardiorenal indices, and c-reactive protein in type 2 diabetes with nephropathy: a longitudinal randomized clinical trial."},"content":{"rendered":"

OBJECTIVE: Several short-term trials on the effect of soy consumption on cardiovascular risks are available, but little evidence exists regarding the impact of long-term soy protein consumption among type 2 diabetic patients with nephropathy. To determine the effects of long-term soy consumption on cardiovascular risks, we measured C-reactive protein (CRP) and kidney function indexes among type 2 diabetic patients with nephropathy. RESEARCH DESIGN AND METHODS: This longitudinal randomized clinical trial was conducted among 41 type 2 diabetic patients with nephropathy (18 men and 23 women). Twenty patients in the soy protein group consumed a diet containing 0.8 g protein\/kg body weight (35% animal proteins, 35% textured soy protein, and 30% vegetable proteins) and 21 patients in the control group consumed a similar diet containing 70% animal proteins and 30% vegetable proteins for 4 years. RESULTS: Soy protein consumption significantly affected cardiovascular risks such as fasting plasma glucose (mean change in the soy protein versus control groups: -18 +\/- 3 vs. 11 +\/- 2 mg\/dl; P = 0.03), total cholesterol (-23 +\/- 5 vs. 10 +\/- 3 mg\/dl; P = 0.01), LDL cholesterol (-20 +\/- 5 vs. 6 +\/- 2 mg\/dl; P = 0.01), and serum triglyceride (-24 +\/- 6 vs. -5 +\/- 2 mg\/dl; P = 0.01) concentrations. Serum CRP levels were significantly decreased by soy protein intake compared with those in the control group (1.31 +\/- 0.6 vs. 0.33 +\/- 0.1 mg\/l; P = 0.02). Significant improvements were also seen in proteinuria (-0.15 +\/- 0.03 vs. 0.02 +\/- 0.01 g\/day; P = 0.001) and urinary creatinine (-1.5 +\/- 0.9 vs. 0.6 +\/- 0.3 mg\/dl, P = 0.01) by consumption of soy protein. CONCLUSIONS: Longitudinal soy protein consumption significantly affected cardiovascular risk factors and kidney-related biomarkers among type 2 diabetic patients with nephropathy.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-45116","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Department of Nutrition, School of Public Health, Isfahan University of Medical Sciences, Isfahan, P.O. Box 81745, Iran. azadbakht@hlth.mui.ac.ir","annee":"2008","mois":"4","numero":"31:4","page":"648-54","auteurs":[{"ID":5899,"post_author":"0","post_date":"2018-12-03 17:32:42","post_date_gmt":"2018-12-03 16:32:42","post_content":"","post_title":"Ahmad Esmaillzadeh","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"ahmad-esmaillzadeh","to_ping":"","pinged":"","post_modified":"2018-12-03 17:32:42","post_modified_gmt":"2018-12-03 16:32:42","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/ahmad-esmaillzadeh\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":45115,"post_author":"0","post_date":"2018-12-04 03:36:56","post_date_gmt":"2018-12-04 02:36:56","post_content":"","post_title":"Atabak","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"atabak","to_ping":"","pinged":"","post_modified":"2018-12-04 03:36:56","post_modified_gmt":"2018-12-04 02:36:56","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/atabak\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":5030,"post_author":"0","post_date":"2018-12-03 17:23:32","post_date_gmt":"2018-12-03 16:23:32","post_content":"","post_title":"Leila Azadbakht","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"leila-azadbakht","to_ping":"","pinged":"","post_modified":"2018-12-03 17:23:32","post_modified_gmt":"2018-12-03 16:23:32","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/leila-azadbakht\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":16521,"post_author":"0","post_date":"2018-12-03 19:40:05","post_date_gmt":"2018-12-03 18:40:05","post_content":"","post_title":"Diabetes care","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"diabetes-care","to_ping":"","pinged":"","post_modified":"2018-12-03 19:40:05","post_modified_gmt":"2018-12-03 18:40:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/diabetes-care\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nSoy protein intake, cardiorenal indices, and c-reactive protein in type 2 diabetes with nephropathy: a longitudinal randomized clinical trial. - 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