{"id":45040,"date":"2008-01-01T00:00:00","date_gmt":"2018-12-04T02:35:56","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/bioactive-food-components-that-enhance-gammadelta-t-cell-function\/"},"modified":"2018-12-04T03:35:56","modified_gmt":"2018-12-04T02:35:56","slug":"bioactive-food-components-that-enhance-gammadelta-t-cell-function","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/bioactive-food-components-that-enhance-gammadelta-t-cell-function\/","title":{"rendered":"Bioactive food components that enhance gammadelta t cell function may play a role in cancer prevention"},"content":{"rendered":"

Gammadelta T cells are found largely within the epithelium and recognize antigens differently than their alphabeta T cell counterparts. TCR delta-\/- knock out mice exhibit a rapid tumor onset, along with increased tumor incidence. Although limited, research demonstrates that nutrients and bioactive food components can influence gammadelta T cell cytotoxicity, cytokine secretion, and proliferative capacity, and the results are nonetheless intriguing. Among other functions, gammadelta T cells play a role in immunosurveillance against malignant cells, as shown by the T cell receptor (TCR)delta-\/- knock out mice that exhibit a rapid tumor onset and increased tumor incidence. Some common dietary modifiers of gammadelta T cell numbers or activity are apple condensed tannins, dietary nucleotides, fatty acids, and dietary alkylamines. A recent clinical study demonstrated that ingesting a fruit and vegetable juice concentrate increased the number of circulating gammadelta T cells. Clinical studies also document that the oral consumption of a tea component, L-theanine, enhances gammadelta T cell proliferation and interferon-gamma secretion. The significance of these studies awaits additional examination of the influence of exposures and duration on these and other food components. Adoptive transfer and TCRdelta-\/- knock out mice models should be used more extensively to determine the physiological impact of the number and activity of these cells as a function of dietary component exposures. While clarifying the diet and gammadelta T interrelationship may not be simple, the societal implications are enormous.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-45040","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Food Science and Human Nutrition, University of Florida, Gainesville, FL 32611, USA. percival@ufl.edu\r\n","annee":"2008","mois":"1","numero":"138:1","page":"1-4","auteurs":[{"ID":34129,"post_author":"0","post_date":"2018-12-04 00:23:23","post_date_gmt":"2018-12-03 23:23:23","post_content":"","post_title":"Susan S Percival","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"susan-s-percival","to_ping":"","pinged":"","post_modified":"2018-12-04 00:23:23","post_modified_gmt":"2018-12-03 23:23:23","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/susan-s-percival\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":45039,"post_author":"0","post_date":"2018-12-04 03:35:55","post_date_gmt":"2018-12-04 02:35:55","post_content":"","post_title":"Bukowski","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"bukowski","to_ping":"","pinged":"","post_modified":"2018-12-04 03:35:55","post_modified_gmt":"2018-12-04 02:35:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/bukowski\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":29511,"post_author":"0","post_date":"2018-12-03 23:19:54","post_date_gmt":"2018-12-03 22:19:54","post_content":"","post_title":"John A Milner","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"john-a-milner","to_ping":"","pinged":"","post_modified":"2018-12-03 23:19:54","post_modified_gmt":"2018-12-03 22:19:54","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/john-a-milner\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":44294,"post_author":"0","post_date":"2018-12-04 03:21:12","post_date_gmt":"2018-12-04 02:21:12","post_content":"","post_title":"JOURNAL OF NUTRITION","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"journal-of-nutrition","to_ping":"","pinged":"","post_modified":"2018-12-04 03:21:12","post_modified_gmt":"2018-12-04 02:21:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/journal-of-nutrition\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":32402,"post_author":"0","post_date":"2018-12-03 23:58:36","post_date_gmt":"2018-12-03 22:58:36","post_content":"","post_title":"J NUTR","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"j-nutr-2","to_ping":"","pinged":"","post_modified":"2018-12-03 23:58:36","post_modified_gmt":"2018-12-03 22:58:36","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/j-nutr-2\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"\nBioactive food components that enhance gammadelta t cell function may play a role in cancer prevention - 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