{"id":42976,"date":"2009-02-01T00:00:00","date_gmt":"2018-12-04T01:59:26","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/"},"modified":"2018-12-04T02:59:26","modified_gmt":"2018-12-04T01:59:26","slug":"longitudinal-biological-exposure-to-carotenoids-is-associated","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/","title":{"rendered":"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women&rsquo;s healthy eating and living study."},"content":{"rendered":"<p>In some cohort studies, a high-vegetable diet has been associated with greater likelihood of recurrence-free survival in women diagnosed with breast cancer. Carotenoids are obtained primarily from vegetables and fruit and they exhibit biological activities that may specifically reduce the progression of mammary carcinogenesis. The present analysis examines the relationship between plasma carotenoids at enrollment and 1, 2 or 3, 4, and 6 years and breast cancer-free survival in the Women&rsquo;s Healthy Eating and Living Study participants (N = 3,043), who had been diagnosed with early-stage breast cancer. The primary end point was time to a second breast cancer event (a recurrence or new primary breast cancer). An average carotenoid concentration over time was estimated for each participant as the average area under the plasma carotenoid curve formed by the plasma carotenoid concentrations at scheduled clinic visits. Multiple regression Cox proportional hazards analysis with adjustment for prognostic and other factors was used to examine the association between carotenoids and breast cancer-free survival. A total of 508 (16.7%) breast cancer events occurred over a median 7.12 years follow-up. Compared with the lowest tertile, the hazard ratio for the medium\/high plasma carotenoid tertiles was 0.67 (95% confidence interval, 0.54-0.83) after adjustment. The interaction between the study group and tertile of average carotenoid concentration over time was not significant (P = 0.23). Higher biological exposure to carotenoids, when assessed over the time frame of the study, was associated with greater likelihood of breast cancer-free survival regardless of study group assignment.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-42976","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Collaborators (27)\r\nCancer Prevention and Control Program, Moores University of California, San Diego Cancer Center, University of California San Diego, La Jolla, CA 92093-0901, USA. clrock@ucsd.edu","annee":"2009","mois":"2","numero":"18:2","page":"486-94","auteurs":[{"ID":26311,"post_author":"0","post_date":"2018-12-03 22:36:30","post_date_gmt":"2018-12-03 21:36:30","post_content":"","post_title":"Loki Natarajan","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"loki-natarajan","to_ping":"","pinged":"","post_modified":"2018-12-03 22:36:30","post_modified_gmt":"2018-12-03 21:36:30","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/loki-natarajan\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":27236,"post_author":"0","post_date":"2018-12-03 22:50:06","post_date_gmt":"2018-12-03 21:50:06","post_content":"","post_title":"Cheryl L Rock","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"cheryl-l-rock","to_ping":"","pinged":"","post_modified":"2018-12-03 22:50:06","post_modified_gmt":"2018-12-03 21:50:06","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/cheryl-l-rock\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":40409,"post_author":"0","post_date":"2018-12-04 02:13:57","post_date_gmt":"2018-12-04 01:13:57","post_content":"","post_title":"Puato","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"puato","to_ping":"","pinged":"","post_modified":"2018-12-04 02:13:57","post_modified_gmt":"2018-12-04 01:13:57","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/puato\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1195,"post_author":"0","post_date":"2018-12-03 15:57:12","post_date_gmt":"2018-12-03 14:57:12","post_content":"","post_title":"CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"cancer-epidemiology-biomarkers-and-prevention","to_ping":"","pinged":"","post_modified":"2018-12-03 15:57:12","post_modified_gmt":"2018-12-03 14:57:12","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/cancer-epidemiology-biomarkers-and-prevention\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women&#039;s healthy eating and living study. - Aprifel<\/title>\n<meta name=\"description\" content=\"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women&#039;s healthy eating and living study. - Aprifel\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women&#039;s healthy eating and living study.\" \/>\n<meta property=\"og:description\" content=\"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women&#039;s healthy eating and living study.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/\" \/>\n<meta property=\"og:site_name\" content=\"Aprifel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/\",\"url\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/\",\"name\":\"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women's healthy eating and living study. - Aprifel\",\"isPartOf\":{\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\"},\"datePublished\":\"2018-12-04T01:59:26+00:00\",\"dateModified\":\"2018-12-04T01:59:26+00:00\",\"description\":\"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women's healthy eating and living study. - Aprifel\",\"breadcrumb\":{\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/www.aprifel.com\/fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"R\u00e9sum\u00e9s\",\"item\":\"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women&rsquo;s healthy eating and living study.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.aprifel.com\/fr\/#website\",\"url\":\"https:\/\/www.aprifel.com\/fr\/\",\"name\":\"Aprifel\",\"description\":\"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women's healthy eating and living study. - Aprifel","description":"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women's healthy eating and living study. - Aprifel","robots":{"index":"noindex","follow":"follow"},"og_locale":"fr_FR","og_type":"article","og_title":"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women's healthy eating and living study.","og_description":"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women's healthy eating and living study.","og_url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/","og_site_name":"Aprifel","twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/","url":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/","name":"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women's healthy eating and living study. - Aprifel","isPartOf":{"@id":"https:\/\/www.aprifel.com\/fr\/#website"},"datePublished":"2018-12-04T01:59:26+00:00","dateModified":"2018-12-04T01:59:26+00:00","description":"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women's healthy eating and living study. - Aprifel","breadcrumb":{"@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/longitudinal-biological-exposure-to-carotenoids-is-associated\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.aprifel.com\/fr\/"},{"@type":"ListItem","position":2,"name":"R\u00e9sum\u00e9s","item":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/"},{"@type":"ListItem","position":3,"name":"Longitudinal biological exposure to carotenoids is associated with breast cancer-free survival in the women&rsquo;s healthy eating and living study."}]},{"@type":"WebSite","@id":"https:\/\/www.aprifel.com\/fr\/#website","url":"https:\/\/www.aprifel.com\/fr\/","name":"Aprifel","description":"Agence pour la Recherche et l\u2019Information en Fruits et L\u00e9gumes","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.aprifel.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"}]}},"_links":{"self":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume\/42976"}],"collection":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/resume"}],"about":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/types\/resume"}],"wp:attachment":[{"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/media?parent=42976"}],"wp:term":[{"taxonomy":"mots_cles","embeddable":true,"href":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/wp-json\/wp\/v2\/mots_cles?post=42976"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}