{"id":42807,"date":"2009-04-01T00:00:00","date_gmt":"2018-12-04T01:56:22","guid":{"rendered":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/dietary-intake-of-fruits-and-vegetables-improves-microvascular\/"},"modified":"2018-12-04T02:56:22","modified_gmt":"2018-12-04T01:56:22","slug":"dietary-intake-of-fruits-and-vegetables-improves-microvascular","status":"publish","type":"resume","link":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/resume-scientifique\/dietary-intake-of-fruits-and-vegetables-improves-microvascular\/","title":{"rendered":"Dietary intake of fruits and vegetables improves microvascular function in hypertensive subjects in a dose-dependent manner."},"content":{"rendered":"<p><strong>BACKGROUND: <\/strong><br \/>\nObservational evidence has consistently linked increased fruit and vegetable consumption with reduced cardiovascular morbidity; however, there is little direct trial evidence to support the concept that fruit and vegetable consumption improves vascular function. This study assessed the dose-dependent effects of a fruit and vegetable intervention on arterial health in subjects with hypertension.<\/p>\n<p><strong>METHODS AND RESULTS: <\/strong><br \/>\nAfter a 4-week run-in period during which fruit and vegetable intake was limited to 1 portion per day, participants were randomized to consume either 1, 3, or 6 portions daily for the next 8 weeks. Endothelium-dependent and -independent arterial vasodilator responses were assessed by venous occlusion plethysmography in the brachial circulation before and after intervention. Compliance was monitored with serial contemporaneous 4-day food records and by measuring concentrations of circulating dietary biomarkers. A total of 117 volunteers completed the 12-week study. Participants in the 1-, 3-, and 6-portions\/d groups reported consuming on average 1.1, 3.2, and 5.6 portions of fruit and vegetables, respectively, and serum concentrations of lutein and beta-cryptoxanthin increased across the groups in a dose-dependent manner. For each 1-portion increase in reported fruit and vegetable consumption, there was a 6.2% improvement in forearm blood flow responses to intra-arterial administration of the endothelium-dependent vasodilator acetylcholine (P=0.03). There was no association between increased fruit and vegetable consumption and vasodilator responses to sodium nitroprusside, an endothelium-independent vasodilator.<\/p>\n<p><strong>CONCLUSIONS: <\/strong><br \/>\nThe present study illustrates that among hypertensive volunteers, increased fruit and vegetable consumption produces significant improvements in an established marker of endothelial function and cardiovascular prognosis.<\/p>\n","protected":false},"template":"","mots_cles":[],"class_list":["post-42807","resume","type-resume","status-publish","hentry"],"acf":{"adresse":"Nutrition and Metabolism Group, Centre for Public Health, Lower Ground Floor, Pathology Bldg, Grosvenor Rd, Belfast, BT12 6BJ, United Kingdom. d.o.mccall@qub.ac.uk","annee":"2009","mois":"4","numero":"119:16","page":"2153-2160","auteurs":[{"ID":6953,"post_author":"0","post_date":"2018-12-03 17:43:45","post_date_gmt":"2018-12-03 16:43:45","post_content":"","post_title":"Michelle C Mckinley","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"michelle-c-mckinley","to_ping":"","pinged":"","post_modified":"2018-12-03 17:43:45","post_modified_gmt":"2018-12-03 16:43:45","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/michelle-c-mckinley\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":9427,"post_author":"0","post_date":"2018-12-03 18:11:02","post_date_gmt":"2018-12-03 17:11:02","post_content":"","post_title":"Damian O McCall","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"damian-o-mccall","to_ping":"","pinged":"","post_modified":"2018-12-03 18:11:02","post_modified_gmt":"2018-12-03 17:11:02","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/damian-o-mccall\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"},{"ID":42806,"post_author":"0","post_date":"2018-12-04 02:56:22","post_date_gmt":"2018-12-04 01:56:22","post_content":"","post_title":"Mcgartland","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"mcgartland","to_ping":"","pinged":"","post_modified":"2018-12-04 02:56:22","post_modified_gmt":"2018-12-04 01:56:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/auteur\/mcgartland\/","menu_order":0,"post_type":"auteur_resume","post_mime_type":"","comment_count":"0","filter":"raw"}],"sources":[{"ID":1456,"post_author":"0","post_date":"2018-12-03 15:59:32","post_date_gmt":"2018-12-03 14:59:32","post_content":"","post_title":"Circulation","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"circulation","to_ping":"","pinged":"","post_modified":"2018-12-03 15:59:32","post_modified_gmt":"2018-12-03 14:59:32","post_content_filtered":"","post_parent":0,"guid":"https:\/\/aprifel-pp.mentalworks.biz\/fr\/source\/circulation\/","menu_order":0,"post_type":"source","post_mime_type":"","comment_count":"0","filter":"raw"}]},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.6 (Yoast SEO v23.6) - 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